NCT00049920

Brief Summary

To perform a follow-up study of cerebrovascular disease in the Atherosclerosis Risk in Communities (ARIC) magnetic resonance imaging subcohort.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,134

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Sep 2002

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2002

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

November 14, 2002

Completed
1 day until next milestone

First Posted

Study publicly available on registry

November 15, 2002

Completed
3.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2006

Completed
2.3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2008

Completed
Last Updated

July 29, 2016

Status Verified

October 1, 2008

Enrollment Period

3.7 years

First QC Date

November 14, 2002

Last Update Submit

July 28, 2016

Conditions

Cardiovascular DiseasesCerebrovascular DisordersCerebrovascular Accident

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Participants in the ARIC Neurocognitive Longitudinal Study were recruited for a follow-up brain MR scan and cognitive testing from the subset of the (parent) ARIC cohort that had an initial MR scan at the third (Visit 3) ARIC examination. Participants included black and white men and women.

Participated in the baseline ARIC MRI study.

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Related Publications (1)

  • Knopman DS, Mosley TH, Catellier DJ, Sharrett AR; Atherosclerosis Risk in Communities (ARIC) Study. Cardiovascular risk factors and cerebral atrophy in a middle-aged cohort. Neurology. 2005 Sep 27;65(6):876-81. doi: 10.1212/01.wnl.0000176074.09733.a8.

    PMID: 16186527BACKGROUND

Biospecimen

Retention: SAMPLES WITH DNA

Plasma and DNA

MeSH Terms

Conditions

Cardiovascular DiseasesCerebrovascular DisordersStroke

Condition Hierarchy (Ancestors)

Brain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular Diseases

Study Officials

  • Thomas H Mosley, PhD

    University of Mississippi Medical Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
NIH

Study Record Dates

First Submitted

November 14, 2002

First Posted

November 15, 2002

Study Start

September 1, 2002

Primary Completion

May 1, 2006

Study Completion

September 1, 2008

Last Updated

July 29, 2016

Record last verified: 2008-10