NCT00021905

Brief Summary

To assess the risk of incident atrial fibrillation after stopping anti-hypertensive medication including beta-blockers and ACE inhibitors. Also, to assess the role of genetics in subsequent risk of stroke among patients with atrial fibrillation.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Jul 2002

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 10, 2001

Completed
Same day until next milestone

First Posted

Study publicly available on registry

August 10, 2001

Completed
11 months until next milestone

Study Start

First participant enrolled

July 1, 2002

Completed
5.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2008

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2008

Completed
Last Updated

July 24, 2008

Status Verified

July 1, 2008

Enrollment Period

5.9 years

First QC Date

August 10, 2001

Last Update Submit

July 23, 2008

Conditions

Atrial FibrillationCardiovascular DiseasesHeart DiseasesHypertensionCerebrovascular AccidentArrhythmia

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
No eligibility criteria

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Related Publications (1)

  • Glazer NL, Smith NL, Heckbert SR, Doggen CJ, Lemaitre RN, Psaty BM. Risk of myocardial infarction attributable to elevated levels of total cholesterol among hypertensives. Am J Hypertens. 2005 Jun;18(6):759-66. doi: 10.1016/j.amjhyper.2004.12.015.

    PMID: 15925732BACKGROUND

MeSH Terms

Conditions

Atrial FibrillationCardiovascular DiseasesHeart DiseasesHypertensionStrokeArrhythmias, Cardiac

Condition Hierarchy (Ancestors)

Pathologic ProcessesPathological Conditions, Signs and SymptomsVascular DiseasesCerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System Diseases

Study Officials

  • Susan Heckbert

    University of Washington

Study Design

Study Type
observational
Sponsor Type
NIH

Study Record Dates

First Submitted

August 10, 2001

First Posted

August 10, 2001

Study Start

July 1, 2002

Primary Completion

June 1, 2008

Study Completion

June 1, 2008

Last Updated

July 24, 2008

Record last verified: 2008-07