NCT00094198

Brief Summary

To assess interactions between selected cardiovascular medications and genes in the incidence of heart attack, stroke, and atrial fibrillation, an irregular heartbeat.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Sep 2003

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2003

Completed
1.1 years until next milestone

First Submitted

Initial submission to the registry

October 15, 2004

Completed
Same day until next milestone

First Posted

Study publicly available on registry

October 15, 2004

Completed
3.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2008

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2008

Completed
Last Updated

August 21, 2008

Status Verified

August 1, 2008

Enrollment Period

4.9 years

First QC Date

October 15, 2004

Last Update Submit

August 20, 2008

Conditions

Cardiovascular DiseasesAtrial FibrillationCerebrovascular AccidentHeart DiseasesMyocardial Infarction

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
No eligibility criteria

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Related Publications (3)

  • Kooperberg C, Ruczinski I. Identifying interacting SNPs using Monte Carlo logic regression. Genet Epidemiol. 2005 Feb;28(2):157-70. doi: 10.1002/gepi.20042.

    PMID: 15532037BACKGROUND

  • Smith NL, Heckbert SR, Lemaitre RN, Reiner AP, Lumley T, Weiss NS, Larson EB, Rosendaal FR, Psaty BM. Esterified estrogens and conjugated equine estrogens and the risk of venous thrombosis. JAMA. 2004 Oct 6;292(13):1581-7. doi: 10.1001/jama.292.13.1581.

    PMID: 15467060BACKGROUND

  • Psaty BM, Furberg CD. Contemplating ACTION--long-acting nifedipine in stable angina. Lancet. 2004 Sep 4-10;364(9437):817-8. doi: 10.1016/S0140-6736(04)16992-4. No abstract available.

    PMID: 15351169BACKGROUND

MeSH Terms

Conditions

Cardiovascular DiseasesAtrial FibrillationStrokeHeart DiseasesMyocardial Infarction

Condition Hierarchy (Ancestors)

Arrhythmias, CardiacPathologic ProcessesPathological Conditions, Signs and SymptomsCerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesMyocardial IschemiaInfarctionIschemiaNecrosis

Study Officials

  • Bruce Psaty

    University of Washington

Study Design

Study Type
observational
Sponsor Type
NIH

Study Record Dates

First Submitted

October 15, 2004

First Posted

October 15, 2004

Study Start

September 1, 2003

Primary Completion

August 1, 2008

Study Completion

August 1, 2008

Last Updated

August 21, 2008

Record last verified: 2008-08