NCT00024596|Completed
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Sponsor study identifier
Secondary identifiers
NIH
observational
3,389
0 countries
N/A
Study Start
September 2001
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
August 2006
Actual (reported)Study Completion
August 2006
Actual (reported)To determine familial and non-familial causes for susceptibility to atherosclerosis and the inflammatory response.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
August 2006
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
September 2001
Date type not reportedThis date has not been verified as actual or estimated.
September 21, 2001
Actual (reported)September 21, 2001
Actual (reported)August 2006
Actual (reported)August 2006
Actual (reported)Largest 3-generational Caucasian Families from Family Heart Study (Classic) with average family size of 10 N=2767 Subjects from 512 families. Approximately half are random sample families from FamHS-Classic, and half are high-familial CHD risk families from FamHS-Classic. 4 Field sites were Raleigh-Durham North Carolina; Minneapolis, MN; Framingham MA; and Salt Lake City, UT.
622 subjects from 2-3 generational 212 African-American families originally recruited from the HyperGEN study in Birmingham AL. These are hypertension enriched families.
Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.
Djousse L, Arnett DK, Carr JJ, Eckfeldt JH, Hopkins PN, Province MA, Ellison RC; Investigators of the NHLBI FHS. Dietary linolenic acid is inversely associated with calcified atherosclerotic plaque in the coronary arteries: the National Heart, Lung, and Blood Institute Family Heart Study. Circulation. 2005 Jun 7;111(22):2921-6. doi: 10.1161/CIRCULATIONAHA.104.489534. Epub 2005 May 31.
Ellison RC, Zhang Y, Wagenknecht LE, Eckfeldt JH, Hopkins PN, Pankow JS, Djousse L, Carr JJ. Relation of the metabolic syndrome to calcified atherosclerotic plaque in the coronary arteries and aorta. Am J Cardiol. 2005 May 15;95(10):1180-6. doi: 10.1016/j.amjcard.2005.01.046.
Stored DNA, lymphoblasts
John Carr
Wake Forest University
John Eckfeldt
University of Minnesota
R. Ellison
Boston University
Gerardo Heiss
University of North Carolina
James Hixson
University of Texas
Steven Hunt
University of Utah
Cora Lewis
University of Alabama at Birmingham
James Pankow
University of Minnesota
Michael Province
Washington University School of Medicine
3,389 participants (actual enrollment reported by the registry).
First Submitted
September 21, 2001
First Posted
September 21, 2001
Study Start
September 2001
Date type not reportedThis date has not been verified as actual or estimated.
Serum Sex Hormone Levels and Subclinical Atherosclerosis - Ancillary to MESA
Lynne Wagenknecht
Wake Forest University
Primary Completion
August 2006
Actual (reported)Study Completion
August 2006
Actual (reported)Last Updated
December 22, 2015
Record last verified: 2015-12
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Source: ClinicalTrials.gov.
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