NCT00063440|Completed
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Sponsor study identifier
Secondary identifiers
observational
5,610
0 countries
N/A
Study Start
June 2003
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
May 2008
Actual (reported)Study Completion
May 2008
Actual (reported)To determine the factors associated with progression of sub-clinical atherosclerosis and to evaluate the associations between the progression of sub-clinical atherosclerosis and the development of clinically manifest atherosclerosis.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
May 2008
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
June 2003
Date type not reportedThis date has not been verified as actual or estimated.
June 26, 2003
Actual (reported)June 30, 2003
Actual (reported)May 2008
Actual (reported)May 2008
Actual (reported)Common carotid artery intima-media thickness
randomly selected at 2 years or 4 years in 1/2 of the cohort
Common carotid artery diameter
randomly selected at 2 or 4 years for each 1/2 of the cohort
Participants of the Multi-Ethnic Study of Atherosclerosis, a cross-sectional NIH population cohort originating from 6 regions in the United States
Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.
Polak JF, Herrington D, O'Leary DH. Associations of edge-detected and manual-traced common carotid artery intima-media thickness with incident peripheral artery disease: The Multi-Ethnic Study of Atherosclerosis. Vasc Med. 2019 Aug;24(4):306-312. doi: 10.1177/1358863X19835925. Epub 2019 Apr 26.
Polak JF, O'Leary DH. Edge-detected common carotid artery intima-media thickness and incident coronary heart disease in the multi-ethnic study of atherosclerosis. J Am Heart Assoc. 2015 Jun 15;4(6):e001492. doi: 10.1161/JAHA.114.001492.
Joseph F Polak, MD, MPH
Tufts Medical Center
5,610 participants (actual enrollment reported by the registry).
First Submitted
June 26, 2003
First Posted
June 30, 2003
Study Start
June 2003
Date type not reportedThis date has not been verified as actual or estimated.
Estrogen Receptor Variants, HDL, and Atherosclerosis
Polak JF, Sacco RL, Post WS, Vaidya D, Arnan MK, O'Leary DH. Incident stroke is associated with common carotid artery diameter and not common carotid artery intima-media thickness. Stroke. 2014 May;45(5):1442-6. doi: 10.1161/STROKEAHA.114.004850. Epub 2014 Mar 18.
Polak JF, Johnson C, Harrington A, Wong Q, O'Leary DH, Burke G, Yanez ND. Changes in carotid intima-media thickness during the cardiac cycle: the multi-ethnic study of atherosclerosis. J Am Heart Assoc. 2012 Aug;1(4):e001420. doi: 10.1161/JAHA.112.001420. Epub 2012 Aug 24.
Polak JF, Wong Q, Johnson WC, Bluemke DA, Harrington A, O'Leary DH, Yanez ND. Associations of cardiovascular risk factors, carotid intima-media thickness and left ventricular mass with inter-adventitial diameters of the common carotid artery: the Multi-Ethnic Study of Atherosclerosis (MESA). Atherosclerosis. 2011 Oct;218(2):344-9. doi: 10.1016/j.atherosclerosis.2011.05.033. Epub 2011 Jun 14.
Primary Completion
May 2008
Actual (reported)Study Completion
May 2008
Actual (reported)Last Updated
February 8, 2013
Record last verified: 2013-02
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Source: ClinicalTrials.gov.
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