NCT00005790

Brief Summary

RATIONALE: Perfusion magnetic resonance imaging may be an effective method of measuring the growth of blood vessels in brain tumors. These measurements may help doctors better diagnose and treat brain tumors. PURPOSE: Pilot study to determine the effectiveness of perfusion magnetic resonance imaging in measuring the growth of blood vessels in newly diagnosed brain tumors.

Trial Health

15
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Apr 1996

Typical duration for not_applicable

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 1996

Completed
3.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 1999

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 1999

Completed
1.1 years until next milestone

First Submitted

Initial submission to the registry

June 2, 2000

Completed
4 years until next milestone

First Posted

Study publicly available on registry

June 9, 2004

Completed
Last Updated

June 11, 2012

Status Verified

June 1, 2012

Enrollment Period

3.1 years

First QC Date

June 2, 2000

Last Update Submit

June 8, 2012

Conditions

Brain and Central Nervous System Tumors

Keywords

adult brain stem gliomaadult ependymomaadult craniopharyngiomaadult medulloblastomaadult meningiomaadult glioblastomaadult oligodendrogliomaadult anaplastic astrocytomaadult myxopapillary ependymomaadult anaplastic ependymomaadult anaplastic oligodendrogliomaadult mixed gliomaadult pineal parenchymal tumoradult central nervous system germ cell tumoradult pilocytic astrocytomaadult subependymomaadult diffuse astrocytomaadult ependymoblastomaadult pineocytomaadult pineoblastomaadult meningeal hemangiopericytomaadult choroid plexus tumoradult grade III meningiomaadult giant cell glioblastomaadult gliosarcoma

Interventions

laboratory biomarker analysisOTHER
biopsyPROCEDURE
magnetic resonance imagingPROCEDURE
gadopentetate dimeglumineRADIATION

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
DISEASE CHARACTERISTICS: Newly diagnosed surgically resectable brain tumor PATIENT CHARACTERISTICS: Age: Over 18 Performance status: Not specified Life expectancy: Not specified Hematopoietic: Not specified Hepatic: Not specified Renal: Not specified Other: Able to tolerate gadopentetate dimeglumine contrast Medically stable PRIOR CONCURRENT THERAPY: Biologic therapy: Not specified Chemotherapy: No prior chemotherapy Endocrine therapy: Not specified Radiotherapy: No prior radiotherapy Surgery: See Disease Characteristics

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

MeSH Terms

Conditions

Central Nervous System NeoplasmsEpendymomaCraniopharyngiomaMedulloblastomaMeningiomaGlioblastomaOligodendrogliomaAstrocytomaGliomaPinealomaGlioma, SubependymalNeuroectodermal Tumors, PrimitiveChoroid Plexus NeoplasmsGliosarcoma

Interventions

BiopsyMagnetic Resonance SpectroscopyGadolinium DTPA

Condition Hierarchy (Ancestors)

Nervous System NeoplasmsNeoplasms by SiteNeoplasmsNervous System DiseasesNeoplasms, NeuroepithelialNeuroectodermal TumorsNeoplasms, Germ Cell and EmbryonalNeoplasms by Histologic TypeNeoplasms, Glandular and EpithelialNeoplasms, Nerve TissueNeoplasms, Vascular TissueMeningeal NeoplasmsBrain NeoplasmsBrain DiseasesCentral Nervous System DiseasesCerebral Ventricle Neoplasms

Intervention Hierarchy (Ancestors)

CytodiagnosisCytological TechniquesClinical Laboratory TechniquesDiagnostic Techniques and ProceduresDiagnosisSpecimen HandlingDiagnostic Techniques, SurgicalSurgical Procedures, OperativeInvestigative TechniquesSpectrum AnalysisChemistry Techniques, AnalyticalPentetic AcidPolyaminesAminesOrganic ChemicalsAcetatesAcids, AcyclicCarboxylic AcidsCoordination Complexes

Study Officials

  • Hunt H. Batjer, MD

    Robert H. Lurie Cancer Center

    STUDY CHAIR
0

Study Design

Study Type
interventional
Phase
not applicable
Purpose
DIAGNOSTIC
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 2, 2000

First Posted

June 9, 2004

Study Start

April 1, 1996

Primary Completion

May 1, 1999

Study Completion

May 1, 1999

Last Updated

June 11, 2012

Record last verified: 2012-06