Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 55/100

Failure Rate

25.0%

5 terminated/withdrawn out of 20 trials

Success Rate

73.7%

-12.8% vs industry average

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

93%

13 of 14 completed trials have results

Key Signals

13 with results

Enrollment Performance

Analytics

Phase 2
14(82.4%)
Phase 1
3(17.6%)
17Total
Phase 2(14)
Phase 1(3)

Activity Timeline

Global Presence

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Clinical Trials (20)

Showing 20 of 20 trials
NCT03462576Terminated

Companion Protocol for Methacetin Breath Test (MBT) in Conatus Protocol IDN-6556-17

Role: collaborator

NCT03439189Completed

Companion Protocol for Methacetin Breath Test (MBT) in Conatus Protocol IDN-6556-14

Role: collaborator

NCT01653899Phase 1Completed

Caspase Inhibition in Islet Transplantation

Role: collaborator

NCT02138253Phase 2Completed

A Trial of IDN-6556 in Post Orthotopic Liver Transplant for Chronic HCV

Role: lead

NCT03479125Terminated

Post-Treatment Follow-up Study for Liver Disease Subjects With or Without Cirrhosis After Receiving Emricasan or Placebo

Role: lead

NCT02686762Phase 2Completed

Emricasan, a Caspase Inhibitor, for Evaluation in Subjects With Non-Alcoholic Steatohepatitis (NASH) Fibrosis

Role: lead

NCT03205345Phase 2Unknown

Emricasan, a Caspase Inhibitor, for Treatment of Subjects With Decompensated NASH Cirrhosis

Role: lead

NCT02230670Phase 2Completed

A Study of IDN-6556 in Subjects With Liver Cirrhosis

Role: lead

NCT02230683Phase 2Completed

A Study of IDN-6556 in Cirrhotic Subjects With Portal Hypertension

Role: lead

NCT01912404Phase 2Terminated

Study of IDN-6556 in Patients With Severe Alcoholic Hepatitis and Contraindications to Steroid Therapy

Role: lead

NCT02077374Phase 2Completed

A Study of IDN-6556 in Subjects With NAFLD and Raised Transaminases

Role: lead

NCT01937130Phase 2Terminated

Pharmacokinetic and Pharmacodynamic Study of IDN-6556 in ACLF

Role: lead

NCT02121860Phase 1Completed

PK and PD Study of IDN-6556 in Subjects With Hepatic Impairment and Matched Healthy Volunteers

Role: lead

NCT02039817Phase 1Completed

PK and PD Study of IDN-6556 in Subjects With Severe Renal Impairment and Matched Healthy Volunteers

Role: lead

NCT00088140Phase 2Completed

A Caspase Inhibitor in Chronic Hepatitis C (HCV) Patients

Role: lead

NCT00080236Phase 2Completed

Safety and Efficacy Study of a Caspase Inhibitor in Patients Undergoing Liver Transplantation

Role: lead

NCT01273064Phase 2Terminated

Standard of Care (SOC) With or Without CTS-1027 in Hepatitis C (HCV) Null-Responders

Role: lead

NCT01051921Phase 2Completed

Study of CTS-1027 in Combination With Pegylated Interferon and Ribavirin in Hepatitis C Virus (HCV) Null-Responders

Role: lead

NCT00925990Phase 2Completed

CTS-1027 in Interferon-Naive Hepatitis C Patients

Role: lead

NCT00570336Phase 2Completed

Study of CTS-1027 in Hepatitis C Patients

Role: lead

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