Hypercholesterolemia
835
22
34
666
Key Insights
Highlights
Success Rate
94% trial completion (above average)
Published Results
198 trials with published results (24%)
Research Maturity
666 completed trials (80% of total)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 30/100
5.1%
43 terminated out of 835 trials
93.9%
+7.4% vs benchmark
36%
304 trials in Phase 3/4
30%
198 of 666 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 666 completed trials
Clinical Trials (835)
A Non-interventional Implementation Study to Evaluate Treatment With Inclisiran (Leqvio®) and Other Lipid Lowering Treatments in a Real-world Setting
WB-EMS Effects on Cardiometabolic Risk Factors
Study of Efficacy, Safety, Tolerability and Quality of Life of Inclisiran (KJX839) vs Placebo, on Top of Ongoing Individually Optimized Lipid-lowering Therapy, in Participants With Hypercholesterolemia
Moderate-Intensity Statin Plus Ezetimibe in CKD and ASCVD
Pharmacogenomic Informed Statin Prescribing
Dachundou No Sugar Added Soymilk for Lipid Modulation
Assessing the Effects of Corn and Avocado Oils on the Cardiometabolic Risk Factor Profile
Triple vs Dual Lipid-Lowering Therapy for LDL-C Reduction in Acute Coronary Syndrome
Long-term Follow-up of Participants Dosed With an Investigational Gene Editing Therapy for Cardiovascular Disease
Causes and Natural History of Dyslipidemias
A Study to Evaluate the Efficacy and Safety of Enlicitide (MK-0616, Oral PCSK9 Inhibitor) Compared With Ezetimibe or Bempedoic Acid or Ezetimibe and Bempedoic Acid in Adults With Hypercholesterolemia (MK-0616-018/CORALreef AddOn)
A Prospective, Open, Observational Study to Confirm the Lipid-lowering Effect, Changes in Glucose Metabolism, and Safety After 6 Months of Administration of Atostazet to Hypercholesterolemic Patients 65 Years of Age or Older
Treatment With Bempedoic Acid and/or Its Fixed-dose Combination With Ezetimibe in Primary Hypercholesterolemia or Mixed Dyslipidemia
Red Yeast Rice for Primary Prevention of Hypercholesterolemia
A Study of Bempedoic Acid/Ezetimibe/High-intensity Statin in Patients Without Cardiovascular Events
Elevated Lipoprotein(a) in Hospital Staff
A Study to See How Safe and Effective Alirocumab is When Given Weekly to Adult Participants Who Have Hypercholesterolemia
Electronic Letters to Improve Patient Activation in IHD: The NUDGE-IHD Trial
Lipoprotein Metabolism in Normal Volunteers and Patients With High Levels of Lipoproteins
Vascular Intervention Strategies Trial for Alzheimer's