The Effect of Chewing Gum on Pain and State Anxiety During Intravenous Blood Sampling

NCT07892365 | Completed

• 1 other identifier: TU2026/5
• Study Type: interventional
• Target: 170
• Locations: 1 country
• Sites: 1

Brief Summary

This study was conducted to investigate the effect of chewing gum during intravenous blood sampling on pain and anxiety levels in individuals.

Conditions

Intravenous Blood Sampling; Pain and Anxiety

Keywords

Intravenous Blood Sampling; Chewing Gum; pain; anxiety; nursing

Outcome Measures

Primary Outcomes (2)

• pain level-Visual Analog Scale (VAS)

  Pain level was assessed using the Visual Analog Scale (VAS) before and after the intravenous blood sampling procedure in both the experimental and control groups.

  Before and immediately after the intravenous blood sampling procedure.

• state anxiety level- state anxiety inventory(STAI-I)

  State anxiety was assessed using the State Anxiety Inventory (STAI-I) before and after the intravenous blood sampling procedure in both the experimental and control groups.

  Before and immediately after the intravenous blood sampling procedure.

Study Arms (2)

Chewing Gum

EXPERIMENTAL

Participants in the experimental group chewed gum during intravenous blood sampling

Procedure: Chewing gum was done during the intravenous blood draw procedure

no gum chewing allowed

NO INTERVENTION

whereas those in the control group received routine care.

Interventions

Chewing gum was done during the intravenous blood draw procedure PROCEDURE

Participants in the experimental group chewed gum during the intravenous blood sampling procedure. Participants in the control group underwent the routine blood sampling procedure without chewing gum. Pain and state anxiety levels were assessed before and after the procedure using the Visual Analog Scale (VAS) and the State Anxiety Inventory (STAI-I).

Chewing Gum

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Volunteers who agreed to participate in the study,
• Individuals who will undergo intravenous blood sampling,
• Aged between 18-65,
• Those who have the cognitive ability to understand and answer the questions during the study,
• Individuals who have not had any blood sampling experience in the past month were included in the study.

You may not qualify if:

• Individuals with any anatomical or functional issues related to the mouth, jaw, temporomandibular joint, or dental health,
• Those with neurological disorders or conditions that could hinder chewing, such as difficulty swallowing (dysphagia),
• Anyone with any skin or vascular problems in the area where the procedure will be done,
• Those with a history of psychiatric medication use or a diagnosed anxiety disorder,
• Individuals who have taken analgesic medication for any reason in the past 24 hours were not included in the study.

Sponsors & Collaborators

• Dicle University: lead

Study Sites (1)

Gercüş Family Health Center in Batman

Batman, Gercüş, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Pain; Anxiety Disorders

Condition Hierarchy (Ancestors)

Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Mental Disorders

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Purpose: SUPPORTIVE CARE
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Nurse

Model Details: This study was conducted to investigate the effect of chewing gum during intravenous blood sampling on pain and anxiety levels in individuals.This study was conducted using a randomized controlled experimental design with a pretest-posttest approach. The sample consisted of 170 individuals (85 in the experimental group and 85 in the control group) who attended the Gercüş Family Health Center in Batman between November 2025 and May 2026, agreed to participate in the study, and met the inclusion criteria.

Study Record Dates

• First Submitted: October 17, 2026
• First Posted: October 23, 2026
• Study Start: October 17, 2025
• Primary Completion: May 22, 2026
• Study Completion: May 22, 2026
• Last Updated: October 23, 2026

Record last verified: 2026-10

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)