Effectiveness of a Mindfulness-Based Cognitive Behavioral Mobile Intervention for Misophonia

NCT07833709 | Not Yet Recruiting

• 2 other identifiers: SK_16092026425K267
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

Misophonia is characterized by strong emotional and physiological reactions to specific trigger sounds and may interfere with daily functioning and emotional well-being. This randomized controlled trial will evaluate the effectiveness of a mobile application based on mindfulness-based cognitive behavioral interventions for adults with misophonia symptoms. A total of 60 participants will be randomly assigned to either an intervention group or a control group. Participants in the intervention group will use a three-week mobile intervention that includes psychoeducation, cognitive behavioral techniques, gradual exposure to trigger sounds, mindfulness, breathing and relaxation exercises, and self-monitoring tools. The control group will not receive the mobile intervention during the study period. Outcomes will be assessed before the intervention, immediately after the three-week intervention, and four weeks after the intervention. The main outcome will be change in misophonia symptoms. Secondary outcomes will include depression, anxiety, stress, and difficulties in emotion regulation.

Conditions

Misophonia; Misophonia Treatment

Keywords

Misophonia; Mindfulness; Cognitive Behavioral Therapy; Mobile Health; mHealth; Digital Intervention; Emotion Regulation; Exposure Therapy; Depression; Anxiety; Stress

Outcome Measures

Primary Outcomes (1)

• Change in Misophonia Scale Total Score

  Misophonia symptoms will be assessed using the 30-item Misophonia Scale developed by Koroglu and Durat (2024). Each item is rated on a 5-point Likert scale, yielding a total score ranging from 30 to 150. Higher scores indicate lower misophonia severity, whereas lower scores indicate greater misophonia severity. Changes in total scores will be compared between the intervention and control groups.

  Baseline, 3 weeks, and 7 weeks

Secondary Outcomes (4)

• Change in DASS-21 Depression Subscale Score

  Baseline, 3 weeks, and 7 weeks

• Change in DASS-21 Anxiety Subscale Score

  Baseline, 3 weeks, and 7 weeks

• Change in DASS-21 Stress Subscale Score

  Baseline, 3 weeks, and 7 weeks

• Change in Difficulties in Emotion Regulation Scale-16 (DERS-16) Total Score

  Baseline, 3 weeks, and 7 weeks

Study Arms (2)

Intervention Group

EXPERIMENTAL

Participants assigned to this arm will use the mindfulness-based cognitive behavioral mobile application for three weeks. The intervention includes psychoeducation, cognitive restructuring, graded exposure to trigger sounds, mindfulness practices, breathing and relaxation exercises, and self-monitoring tools.

Behavioral: Mindfulness-Based Cognitive Behavioral Mobile Intervention

Control Group

NO INTERVENTION

Participants assigned to this arm will not receive the mobile intervention during the study period. They will complete the same outcome assessments as the intervention group at baseline, post-intervention, and follow-up.

Interventions

Mindfulness-Based Cognitive Behavioral Mobile Intervention BEHAVIORAL

A three-week mobile behavioral intervention developed for adults with misophonia symptoms. The intervention integrates psychoeducation, cognitive behavioral techniques, self-monitoring, cognitive restructuring, graded exposure to trigger sounds, Subjective Units of Distress Scale (SUDS) monitoring, mindfulness practices, breathing exercises, relaxation techniques, and supportive audio content. The program is designed to target maladaptive thoughts, avoidance behaviors, emotional reactivity, physiological arousal, and difficulties in emotion regulation associated with misophonia.

Intervention Group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age 18 years or older.
• Meeting the misophonia criteria proposed by Jager et al. (2020).
• Reporting at least one trigger sound.
• Having a Misophonia Scale total score greater than 60.5.
• Owning a smartphone or tablet.
• Having sufficient technological literacy to use the mobile application.

You may not qualify if:

• Misophonia symptoms being better explained by another condition or disorder based on the eligibility screening.
• A Misophonia Scale total score of 60.5 or lower.
• Development of marked distress or functional impairment during the study that requires discontinuation and referral for professional mental health support.

Sponsors & Collaborators

• Sakarya University: lead
• The Scientific and Technological Research Council of Turkey: collaborator

Study Sites (1)

Sakarya University, Faculty of Health Sciences

Sakarya, Sakarya Üniversitesi, 54050, Turkey (Türkiye)

Location

MeSH Terms

Conditions

misophonia; Emotional Regulation; Depression; Anxiety Disorders

Condition Hierarchy (Ancestors)

Self-Control; Social Behavior; Behavior; Behavioral Symptoms; Mental Disorders

Central Study Contacts

Sevgi Koroglu Gokbel, Research Assistant

CONTACT

+90 264 295 74 28; sevgikoroglu@sakarya.edu.tr

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Model Details: Participants will be randomized in parallel to an intervention group or a control group.

Study Record Dates

• First Submitted: September 16, 2026
• First Posted: September 22, 2026
• Study Start (Estimated): October 15, 2026
• Primary Completion (Estimated): December 3, 2026
• Study Completion (Estimated): December 3, 2026
• Last Updated: September 25, 2026

Record last verified: 2026-09

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)