The Efficacy of Lavender Herbal Tea in Misophonia

NCT06785649 | Not Yet Recruiting

• 1 other identifier: 3-1-2024-SK
• Study Type: interventional
• Target: 60
• Locations: 0 countries
• Sites: N/A

Brief Summary

Misophonia is a disorder characterized by a high level of annoyance with certain sounds. Exposure to these sounds causes physical symptoms characterized by anger, aggression, helplessness, overwhelm, and stimulation of the sympathetic nervous system. These emotional and physical reactions can lead to a decline in family relationships, work and school productivity, withdrawal from social relationships, and even suicide. There is limited empirical evidence evaluating the efficacy of therapeutic approaches to misophonia. This limited empirical evidence consists of pharmacological agents such as selective serotonin reuptake inhibitors, stimulants, antipsychotics, and β-Blockers, as well as cognitive behavioral therapy, acceptance and commitment therapy, and dialectical behavior therapy. Complementary therapies are important because of their potential efficacy, tolerability, possible non-interference, and low cost. The fact that lavender has anxiolytic, antidepressant, neuroprotective, and anti-inflammatory properties may affect the emotional and physical responses elicited by misophonia. Therefore, within the scope of the study, misophonia individuals will be divided into two groups; one group will use lavender tea for 14 days and the other group will form a waiting list. The study data will be collected by 'Information Collection Form', 'Misophonia Scale', 'Beck Depression Inventory-II', 'Anxiety Rating Scale', and 'Trait Anger Scale'. SPSS 25.0 software will be used to analyze the data obtained from the research. Considering the limitations of therapeutic approaches for misophonia, testing the effectiveness of lavender in reducing misophonia symptoms will make an important contribution to the literature.

Conditions

Misophonia; Misophonia Treatment; Anxiety; Depression; Anger; Complementary Medicine

Keywords

misophonia; anxiety; depression; anger; lavender

Outcome Measures

Primary Outcomes (1)

• Misophonia Scale

  It is a 30-item self-report scale aiming to assess the severity of misophonia. The scale is a 5-point Likert-type scale and is graded between 1: Strongly agree and 5: Strongly disagree to 5: Strongly disagree. The total score range is 30 - 150. As the score obtained from the scale decreases, the level of misophonia severity decreases.

  Within the first 24 hours after 14 days of lavender tea

Secondary Outcomes (3)

• Beck Depression Inventory-II (BDI-II)

  Within the first 24 hours after 14 days of lavender tea

• Anxiety Assessment Scale

  Within the first 24 hours after 14 days of lavender tea

• Trait Anger Scale (SL-Anger)

  Within the first 24 hours after 14 days of lavender tea

Study Arms (2)

Experimental group (lavender herbal tea)

EXPERIMENTAL

Each participant will be allocated 14 pieces of lavender tea bags of 2 grams, originating from Turkey. The intervention group will be advised to use 2 g of lavender herb infused in 300 mL hot water for 10-15 minutes in the morning and evening for 14 days. Participants will be advised to take some time and inhale the scent before drinking the herbal tea.

Other: Lavender herbal tea

Control group (wait-list)

NO INTERVENTION

No intervention will be applied to the control group for 14 days.

Interventions

Lavender herbal tea OTHER

The participant will be allocated 14 pieces of lavender tea bags consisting of 2 grams and originating from Turkey. During 14 days, the participant will be advised to use 2 g of lavender herb brewed in 300 mL hot water for 10-15 minutes in the morning and evening. Participants will be able to use 1 lavender tea bag twice a day.

Experimental group (lavender herbal tea)

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Reporting at least three trigger sounds
• Assessed by a specialist psychiatric nurse and a psychiatrist as humophonia based on the diagnostic criteria for humophonia established by Schröder et al. (2013)
• Individuals aged 18 and over

You may not qualify if:

• Allergy to any herbal tea, food or medicine
• Psychiatric illness or chronic illness
• Taking psychiatric medication (such as anxiolytics, and antidepressants)
• Regular use of medication (such as antihypertensive, antidiabetic)
• Regular use of herbal teas or complementary medicines
• Tinnitus and/or hyperacusis

Sponsors & Collaborators

• Sakarya University: lead

Related Publications (12)

• Kianpour M, Moshirenia F, Kheirabadi G, Asghari G, Dehghani A, Dehghani-Tafti A. The Effects of Inhalation Aromatherapy with Rose and Lavender at Week 38 and Postpartum Period on Postpartum Depression in High-risk Women Referred to Selected Health Centers of Yazd, Iran in 2015. Iran J Nurs Midwifery Res. 2018 Sep-Oct;23(5):395-401. doi: 10.4103/ijnmr.IJNMR_116_16.

  PMID: 30186346 BACKGROUND

• Firoozeei TS, Feizi A, Rezaeizadeh H, Zargaran A, Roohafza HR, Karimi M. The antidepressant effects of lavender (Lavandula angustifolia Mill.): A systematic review and meta-analysis of randomized controlled clinical trials. Complement Ther Med. 2021 Jun;59:102679. doi: 10.1016/j.ctim.2021.102679. Epub 2021 Feb 4.

  PMID: 33549687 BACKGROUND

• Su S, Wang Y, Jiang W, Zhao W, Gao R, Wu Y, Tao J, Su Y, Zhang J, Li K, Zhang Z, Zhao M, Wang Z, Luo Y, Huang X, Wang L, Wang X, Li Y, Jia Q, Wang L, Li H, Huang J, Qiu J, Xu Y. Efficacy of Artificial Intelligence-Assisted Psychotherapy in Patients With Anxiety Disorders: A Prospective, National Multicenter Randomized Controlled Trial Protocol. Front Psychiatry. 2022 Jan 20;12:799917. doi: 10.3389/fpsyt.2021.799917. eCollection 2021.

  PMID: 35126211 BACKGROUND

• Rappoldt LR, van der Pol MM, de Wit C, Slaghekke S, Houben C, Sondaar T, Kan KJ, van Steensel FJAB, Denys D, Vulink NCC, Utens EMWJ. Effectiveness of an innovative treatment protocol for misophonia in children and adolescents: Design of a randomized controlled trial. Contemp Clin Trials Commun. 2023 Mar 11;33:101105. doi: 10.1016/j.conctc.2023.101105. eCollection 2023 Jun.

  PMID: 36950304 BACKGROUND

• Jager IJ, Vulink NCC, Bergfeld IO, van Loon AJJM, Denys DAJP. Cognitive behavioral therapy for misophonia: A randomized clinical trial. Depress Anxiety. 2020 Dec 18;38(7):708-18. doi: 10.1002/da.23127. Online ahead of print.

  PMID: 33336858 BACKGROUND

• Cowan, E. N., Marks, D. R., & Pinto, A. Misophonia: A psychological model and proposed treatment. Journal of Obsessive-Compulsive and Related Disorders, 32, 100691. https://doi.org/10.1016/j.jocrd.2021.100691

  BACKGROUND

• Jager I, de Koning P, Bost T, Denys D, Vulink N. Misophonia: Phenomenology, comorbidity and demographics in a large sample. PLoS One. 2020 Apr 15;15(4):e0231390. doi: 10.1371/journal.pone.0231390. eCollection 2020.

  PMID: 32294104 BACKGROUND

• Cassiello-Robbins C, Anand D, McMahon K, Brout J, Kelley L, Rosenthal MZ. A Preliminary Investigation of the Association Between Misophonia and Symptoms of Psychopathology and Personality Disorders. Front Psychol. 2021 Jan 14;11:519681. doi: 10.3389/fpsyg.2020.519681. eCollection 2020.

  PMID: 33519567 BACKGROUND

• Erfanian M, Kartsonaki C, Keshavarz A. Misophonia and comorbid psychiatric symptoms: a preliminary study of clinical findings. Nord J Psychiatry. 2019 May-Jul;73(4-5):219-228. doi: 10.1080/08039488.2019.1609086. Epub 2019 May 8.

  PMID: 31066600 BACKGROUND

• Brout JJ, Edelstein M, Erfanian M, Mannino M, Miller LJ, Rouw R, Kumar S, Rosenthal MZ. Investigating Misophonia: A Review of the Empirical Literature, Clinical Implications, and a Research Agenda. Front Neurosci. 2018 Feb 7;12:36. doi: 10.3389/fnins.2018.00036. eCollection 2018.

  PMID: 29467604 BACKGROUND

• Swedo SE, Baguley DM, Denys D, Dixon LJ, Erfanian M, Fioretti A, Jastreboff PJ, Kumar S, Rosenthal MZ, Rouw R, Schiller D, Simner J, Storch EA, Taylor S, Werff KRV, Altimus CM, Raver SM. Consensus Definition of Misophonia: A Delphi Study. Front Neurosci. 2022 Mar 17;16:841816. doi: 10.3389/fnins.2022.841816. eCollection 2022.

  PMID: 35368272 BACKGROUND

• Koroglu Gokbel S, Durat G. The effect of lavender herbal tea on the mental health of individuals with misophonia: A randomized controlled trial. J Psychiatr Res. 2026 Jan 21;195:39-46. doi: 10.1016/j.jpsychires.2026.01.028. Online ahead of print.

  PMID: 41579454 DERIVED

MeSH Terms

Conditions

misophonia; Anxiety Disorders; Depression

Condition Hierarchy (Ancestors)

Mental Disorders; Behavioral Symptoms; Behavior

Central Study Contacts

Sevgi Koroglu, MSc

CONTACT

05367982320; sevgikoroglu@sakarya.edu.tr

Gülgün Durat, PhD

CONTACT

0264 295 66 12; gdurat@sakarya.edu.tr

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: The waiting list group, which is the control group, will not undergo any intervention. The experimental group will use lavender herbal tea in the morning and evening for 14 days.

Study Record Dates

• First Submitted: January 4, 2025
• First Posted: January 21, 2025
• Study Start: February 1, 2025
• Primary Completion: February 1, 2025
• Study Completion: February 28, 2025
• Last Updated: January 21, 2025

Record last verified: 2025-01

Data Sharing

• IPD Sharing: Will not share