Psychological Intervention for Misophonia

NCT05601284 | Active Not Recruiting

• 1 other identifier: 12981
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The investigators are proposing to test Acceptance and Commitment Therapy (ACT)+ traditional audiological behavioral intervention as an integrated, multi-disciplinary approach for the assessment and treatment of misophonia. Participants will be 60 adults with misophonia and will be randomly assigned to receive 12 sessions of ACT+behavioral intervention or receive 12 weeks of progressive relaxation training+psychoeducation (PRT; a commonly used active control condition) after undergoing a comprehensive psychological and audiological evaluation.

Conditions

Misophonia

Outcome Measures

Primary Outcomes (1)

• Misophonia Questionnaire

  Self-report of misophonia symptoms. There are two subscales. The first subscale (misophonia symptoms) ranges from 0 to 76 and the second (misophonia severity) ranges from 1 to 15. For both subscales, higher scores indicate worse outcomes.

  9-12 months

Study Arms (2)

Acceptance and commitment therapy

EXPERIMENTAL

ACT teaches skills to develop acceptance, mindfulness, and defusion from difficult internal experiences while increasing connections with personal values and encouraging meaningful behavioral changes. ACT for misophonia combines core ACT processes with a traditional audiological behavioral intervention for a integrated, multi-disciplinary approach for the assessment and treatment of misophonia. Treatment begins with a brief focus on the behavioral intervention, followed by the teaching of ACT skills to support the use of the behavioral methods. The intervention consists of 12 total individual sessions of ACT+behavioral management.

Behavioral: Acceptance and commitment therapy

Progressive relaxation training

ACTIVE COMPARATOR

PRT for misophonia consists of basic psychoeducation for misophonia followed by PRT. PRT involves learning to tense and relax muscles. Early sessions focus on tensing and relaxing smaller muscle groups, while later sessions focus on larger muscle groups. Final sessions focus on relaxation as produced by recalling previous relaxation and a review of skills learned. PRT consists of 12 individual total sessions.

Behavioral: Progressive relaxation training

Interventions

Acceptance and commitment therapy BEHAVIORAL

ACT teaches skills to develop acceptance, mindfulness, and defusion from difficult internal experiences while increasing connections with personal values and encouraging meaningful behavioral changes. ACT for misophonia combines core ACT processes with a traditional audiological behavioral intervention for a integrated, multi-disciplinary approach for the assessment and treatment of misophonia. Treatment begins with a brief focus on the behavioral intervention, followed by the teaching of ACT skills to support the use of the behavioral methods. The intervention consists of 12 total individual sessions of ACT+behavioral management.

Also known as: ACT

Acceptance and commitment therapy

Progressive relaxation training BEHAVIORAL

PRT for misophonia consists of basic psychoeducation for misophonia followed by PRT. PRT involves learning to tense and relax muscles. Early sessions focus on tensing and relaxing smaller muscle groups, while later sessions focus on larger muscle groups. Final sessions focus on relaxation as produced by recalling previous relaxation and a review of skills learned. PRT consists of 12 individual total sessions.

Also known as: PRT

Progressive relaxation training

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Individuals seeking treatment for misophonia.
• Meet clinical cut-off for misphonia (minimum score of five on the Misophonia Questionnaire).
• Stable on psychotropic medication for at least 30 days.
• English speaking.

You may not qualify if:

• Presence of psychological and/or neurological impairments that would preclude someone from participating in the study or exceed misophonia as the primary presenting problem (e.g. active self-harm or need for treatment for psychosis).

Sponsors & Collaborators

• Utah State University: lead

Study Sites (1)

Utah State University

Logan, Utah, 84341, United States

Location

MeSH Terms

Conditions

misophonia

Interventions

Acceptance and Commitment Therapy; Autogenic Training

Intervention Hierarchy (Ancestors)

Cognitive Behavioral Therapy; Behavior Therapy; Psychotherapy; Behavioral Disciplines and Activities; Hypnosis; Mind-Body Therapies; Complementary Therapies; Therapeutics

Study Officials

• Michael Twohig, PhD

  Utah State University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 26, 2022
• First Posted: November 1, 2022
• Study Start: October 24, 2022
• Primary Completion: October 30, 2025
• Study Completion: April 30, 2026
• Last Updated: July 26, 2024

Record last verified: 2023-12

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)