NCT07797972

Active Not Recruiting

Prospective Clinical Evaluation of Posterior Single-tooth Zi...

University of Pennsylvania Source

Compare

Other study identifiers

Sponsor study identifier

20-0251(842650)

Study Type

observational

Estimated enrollment

40

Locations

1 country

Sites

1

Timeline

Study Start

May 9, 2022

Actual (reported)

Primary Completion

December 2026

Estimated

Planned date reported by the registry; this milestone is not confirmed as achieved.

Study Completion

December 2026

Estimated

Planned date reported by the registry; this milestone is not confirmed as achieved.

Brief Summary

This prospective, controlled, open clinical product surveillance trial will evaluate the performance of posterior zirconia ceramic crowns over 24 months

Registry Overview

Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.

Recruitment status: active not recruiting
Estimated enrollment: 40 participants
Study completion date: December 2026
Estimated
Planned date reported by the registry; this milestone is not confirmed as achieved.
Listed locations: 1 countries · 1 sites

Trial Relationships

Click on a node to explore related trials.

Some registry-reported names shown below are not yet linked in this graph.

Study Timeline

Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.

Study Start
May 9, 2022
Actual (reported)
First Submitted
August 17, 2026
Actual (reported)
First Posted
September 1, 2026
Actual (reported)
Primary Completion
December 2026
Estimated
Planned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
December 2026
Estimated
Planned date reported by the registry; this milestone is not confirmed as achieved.

Last Updated: September 1, 2026
Status Verified: August 2026
Last Update Submitted: August 28, 2026

Conditions

Dental Crowns

Keywords

dental

Outcome Measures

Primary Outcomes (1)

Survival analysis
Survival analysis will be estimated using Kaplan-Meier survival analysis. Based on the following variables; restoration loss and FDI criteria (Marginal fit, Shade/Color Match, and Incidence of complications)
From day 1 of crown placement to follow-up visits at 6, 12, and 24 months.

Study Arms (1)

Patients receiving receiving zirconia ceramic restorations

Combination Product: IPS e.max® ZirCAD Prime Esthetic

Interventions

IPS e.max® ZirCAD Prime EstheticCombination product

Full-coverage crowns will be fabricated from zirconia ceramic discs (IPS e.max® ZirCAD Prime Esthetic, Ivoclar Vivadent, Schaan, Liechtenstein) and cemented with ZirCAD Cement (Ivoclar Vivadent) a resin modified glass ionomer luting cement.

Patients receiving receiving zirconia ceramic restorations

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years+

Sexall

Age GroupsAdult (18-64), Older Adult (65+)

Sampling MethodNon-Probability Sample

Study Population

Recruitment will be conducted by advertisements in local newspapers and at academic institutions. Patients will also be recruited from within Penn Dental Medicine's undergraduate and postgraduate student clinics.

You may qualify if:

At least 18 years of age (selected regardless of sex, race or other ethnic characterization)

Sponsors & Collaborators

Ivoclar Vivadent AG
Industrycollaborator
University of Pennsylvania
Otherlead

Study Sites (1)

Penn Dental Medicine

Philadelphia, Pennsylvania, 19104, United States

Study Design

Study Type: observational
Observational Model: COHORT
Time Perspective: PROSPECTIVE
Target Duration: 2 Years
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

August 17, 2026

First Posted

September 1, 2026

Study Start

May 9, 2022

Actual (reported)

Primary Completion

December 2026

Estimated

Planned date reported by the registry; this milestone is not confirmed as achieved.

NCT06564337

A Prospective Clinical Trial Evaluating Outcomes of Surveyed Zirconia Crowns

Not ApplicableNot Yet Recruiting

NCT03283709

Removable Partial Denture Abutments Restored With Monolithic Zirconia Crowns

Not ApplicableTerminated

NCT06496828

Clinical Outcomes of Biologically Oriented Preparation Technique

Not ApplicableRecruiting

NCT05471024

Occlusal Adjustment Time and Volume for Single Unit Fixed Prosthesis Fabricated With Different Virtual Mounting

Not ApplicableCompleted

NCT02758457

Zirconia and Metal-based Single Crown Posterior Restorations.

Phase 4Completed

NCT06856005

"Assessing the Impact of Personalized Music Playlists on Procedural Anxiety and Crown Preparation Performance Among Young Dentists: A Randomized Controlled Trial"

Not ApplicableCompleted

Vital or endodontically treated tooth

Antagonist present

Classify as ASA I or ASA II according to the American Society of Anesthesiologists (ASA)

In need of an indirect full-coverage restoration (crown) on at least one posterior tooth (premolar or molar)

Fulfilling all medical and dental requirements for preparation of a full-coverage crown

Angle Class I occlusal relationship with a minimum of 20 remaining teeth

Adequate intra-arch space allowing for satisfactory restoration of the abutment teeth. If opposing teeth have supra-erupted, an ideal occlusal plane will be restored by enameloplasty. In cases of severe supra-eruption, patients will need to consent to alternative means of restoring an ideal plane of occlusion. This may involve surgical crown lengthening and/or restoration of the tooth. Otherwise, they will be excluded from the study.

Dentition free of active periodontal disease (probing depth and attachment levels at within normal limits, no furcation involvement, no mobility). Individuals meeting other criteria but presenting with active periodontal disease will be referred to the Post-Graduate Periodontal Clinic for treatment and subsequently re-screened.

Willingness and ability to comply with the pre- and post-operative diagnostic and clinical evaluations required for the study.

Willingness and ability (including financial) to comply with the final restorative treatment plan that will be accomplished upon completion of participation in the study.

Willingness and ability to understand and comply with Institutional Review Board (IRB)/Ethics Committee requirements as outlined in consent forms, which have to be signed by the patients.

Subjects are responsible for payment of regular dental procedures.

You may not qualify if:

Severe wear facets and/or parafunctional activities such as clenching or nocturnal bruxism
Pulpitis, no hypersensitivity on biting and temperature (visual analog scale \<3)
Insufficient endodontic treatment
Periapical pathology
Pregnancy during the treatment phase
Significant medical conditions or drug use that could interfere with evaluation (i.e., narcotics, NSAIDs)
Medical conditions that preclude the subject from carrying out oral hygiene regimens (i.e., severe arthritis affecting the hands)
Social history that indicates a risk of poor compliance (i.e., history of alcohol or drug abuse) with proper maintenance of restoration

Contact the study team to confirm eligibility.

Study Completion

December 2026

Estimated

Planned date reported by the registry; this milestone is not confirmed as achieved.

Last Updated

September 1, 2026

Record last verified: 2026-08

Source record

Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.

Source: ClinicalTrials.gov.

JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.

Registry identifier: NCT07797972
Data provider: ClinicalTrials.gov
Source updated: 2026-09-01
Normalization version: ctgov-legacy-1

Open registry record

Source retrieved: 2026-10-25 22:40:34 UTC

Locations

US(1)

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Study Arms (1)

Patients receiving receiving zirconia ceramic restorations

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations