A Comparative Clinical Study to Evaluate Crowns Designed by Artificial Intelligence Versus Crowns Designed Traditional Design Software

NCT07099261 | Not Yet Recruiting DMC

• 1 other identifier: Tishreen U ـProsthodontics
• Study Type: interventional
• Target: 10
• Locations: 0 countries
• Sites: N/A

Brief Summary

This clinical research aims to Evaluate Crowns Designed by Artificial Intelligence Versus Crowns Designed by Traditional Design Software The research will be conducted on a sample of patients with an indication for crowning of the first lower molar. Ten dental crowns will be prepared. After obtaining written consent from patients who meet the inclusion and exclusion criteria, 10 dental crowns will be prepared. Measurements will be taken using silicone impressions and then converted into digital format. The digital impression will be sent to the selected dental restoration design software used in the study. The same parameters will be adjusted in all software programs for each crown. After the design is completed, the designs will be sent to the milling unit. For each case, three crowns will be designed and milled from polymethyl methacrylate (PMMA). The crown will be clinically examined and evaluated according to specific criteria. Marginal fit, proximal contact quality, and occlusion will be assessed. The best crown will be milled from zirconia and delivered to the patient.

Conditions

Dental Crown

Keywords

Crowns; Crowns Designed by Artificial Intelligence; Artificial intelligence(AI); CAD; CAD\CAM; computer-aided design and computer-aided manufacturing; prosthesis

Outcome Measures

Primary Outcomes (3)

• Marginal Fit

  Evaluation is conducted by 2 dentists to determine whether the restoration is clinically acceptable or unacceptable using an explorer or The silicone replica technique (Silicone Replica Technique) is used to evaluate the marginal fit of crowns using silicone material or Evaluation is conducted using Geomagic X

  immediately after delivering the crown

• Clinical evaluation of proximal contact points

  To evaluate the interproximal contact points of the crown clinically using waxed dental floss: if the floss passes with slight resistance, the contact points are considered acceptable if the floss passes without resistance, the contact points are considered unacceptable if the floss hard to pass or tearing, the contact points are considered Tight Contact

  immediately after delivering the crown

• clinical evaluation of the occlusion

  Clinical Evaluation of Occlusion Using Articulating Paper Excellent (both 100- and 12-mm articulating paper imprints exist on the crown and adjacent teeth) nice occlusal contact distribution Good (only 100-mm articulating paper imprints exist on adjacent teeth) Individual occlusal contact points missing or deviated but occlusal contacts on main supporting cusp Satisfactory crown too high, thus supra occlusion No occlusal contacts on supporting cusps but contacts present on other parts of occlusal surface Unsatisfactory No occlusal contact points on crown(infra occlusion)

  immediately after delivering the crown

Study Arms (3)

Crowns designed with AI powered dentibird

EXPERIMENTAL

10 Crowns designed with AI powered dentbird

Other: Crowns

Crowns designed with AI powered Exocad

EXPERIMENTAL

10 Crowns designed with AI powered Exocad

Other: Crowns

Crowns designed with conventional Exocad

SHAM COMPARATOR

10 Crowns designed with conventional Exocad (computer aided experienced)

Other: Crowns

Interventions

Crowns OTHER

1. Tooth Preparation: Prepare the teeth to receive a zirconia crown. 2. Impression Taking: Obtain impressions using silicone. 3. Digital Conversion: Convert impressions into a digital model using a laboratory scanner. 4. Design Submission: Send the digital model to selected crown design program. 5. Crown Fabrication: crowns designed will be produced from PMMA using a milling unit. 6. Clinical Evaluation: Conduct a clinical assessment of the crowns 7. the best crown design will be milled from zirconia and delivered Evaluation of Crowns designed by following metrics: 1. Marginal fit 2. proximal contact 3. Occlusion

Also known as: dental crowns

Crowns designed with AI powered Exocad; Crowns designed with AI powered dentibird; Crowns designed with conventional Exocad

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Patients aged 18-60 years requiring a crown for a lower first molar
• Good oral and gingival health
• adjacent teeth in good condition
• Natural opposing teeth
• Willingness to participate and sign informed consent

You may not qualify if:

• Abnormal occlusal habits such as bruxism
• Active periodontal diseases
• Allergy to crown materials (e.g., polymethyl methacrylate, PMMA)
• Poor oral hygiene

Sponsors & Collaborators

• Tishreen University: lead

Related Links

• Evaluation of the accuracy, occlusal contact and clinical applications of zirconia crowns using artificial intelligence design versus human design
• Impact of different CAD software programs on marginal and internal fit of provisional crowns: An in vitro study
• Time efficiency, occlusal morphology, and internal fit of anatomic contour crowns designed by dental software powered by generative adversarial network: A comparative study
• Verification of the accuracy and design time of crowns designed with artificial intelligence

MeSH Terms

Interventions

Crowns

Intervention Hierarchy (Ancestors)

Dental Prosthesis; Prosthodontics; Dentistry; Prostheses and Implants; Equipment and Supplies

Study Officials

• Zeyad Handhal, master's student

  Tishreen University

  PRINCIPAL INVESTIGATOR

• Rima Saker, Assistant professor

  Tishreen University

  STUDY CHAIR

Central Study Contacts

Zeyad Handhal, master's student

CONTACT

00963981898264; zeyad.handhal@tishreen.edu.sy

Rima Saker, Assistant professor

CONTACT

00963949831419; rima.saker@tishreen.edu.sy

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: self controlled clinical trial

Study Record Dates

• First Submitted: July 20, 2025
• First Posted: August 1, 2025
• Study Start: October 1, 2025
• Primary Completion (Estimated): August 1, 2026
• Study Completion (Estimated): September 1, 2026
• Last Updated: August 1, 2025

Record last verified: 2025-07