Full-Mouth vs. Quadrant-Wise Scaling and Root Planing: Clinical Effectiveness, Environmental Sustainability, and Patient-Reported Outcomes

NCT07785115 | Active Not Recruiting

• 1 other identifier: SelcukU-DHF-NK-01
• Study Type: interventional
• Target: 52
• Locations: 1 country
• Sites: 1

Brief Summary

This randomized clinical trial compares full-mouth and quadrant-wise scaling and root planing in patients with Stage III periodontitis. In addition to evaluating clinical effectiveness and patient-reported outcomes, the study investigates the environmental sustainability of both treatment protocols using life cycle assessment. The findings are expected to contribute to more sustainable and patient-centered periodontal treatment planning.

Conditions

Stage III Periodontitis

Keywords

Periodontitis, scaling and root planing, life cycle assessment, patient-reported outcomes, environmental sustainability

Outcome Measures

Primary Outcomes (1)

• Probing Pocket Depth (PPD)

  Mean probing pocket depth (PPD) was measured at six sites per tooth using a manual periodontal probe and recorded in millimeters (mm). Lower PPD values indicate improved periodontal status.

  Baseline, 1 month, 3 months, and 6 months

Secondary Outcomes (11)

• Clinical Attachment Level (CAL)

  Baseline, 1 month, 3 months, and 6 months

• Bleeding on Probing (BOP)

  Baseline, 1 month, 3 months, and 6 months

• Plaque Index (PI)

  Baseline, 1 month, 3 months, and 6 months

• Gingival Index (GI)

  Baseline, 1 month, 3 months, and 6 months

• Periodontal Inflamed Surface Area (PISA)

  Baseline, 1 month, 3 months, and 6 months

Study Arms (2)

Full-Mouth Scaling and Root Planing (FM-SRP)

ACTIVE COMPARATOR

Participants received full-mouth scaling and root planing completed in a single treatment session. Periodontal clinical parameters, patient-reported outcomes, and environmental sustainability outcomes were evaluated during a 6-month follow-up period.

Procedure: Full-Mouth Scaling and Root Planing

Quadrant-Wise Scaling and Root Planing (Q-SRP)

ACTIVE COMPARATOR

Participants received quadrant-wise scaling and root planing performed over four treatment sessions at one-week intervals. Clinical effectiveness, patient-reported outcomes, and environmental sustainability were evaluated during a 6-month follow-up period.

Procedure: Quadrant-Wise Scaling and Root Planing

Interventions

Full-Mouth Scaling and Root Planing PROCEDURE

Full-mouth scaling and root planing was completed in a single treatment session using ultrasonic scalers and Gracey curettes. Standardized oral hygiene instructions were provided before treatment. Participants were re-evaluated at 1-, 3-, and 6-month follow-up visits, and additional non-surgical periodontal treatment was provided for sites requiring further therapy when clinically indicated.Clinical outcomes, patient-reported outcomes, and the environmental impact of the treatment protocol were assessed throughout the study.

Full-Mouth Scaling and Root Planing (FM-SRP)

Quadrant-Wise Scaling and Root Planing PROCEDURE

Quadrant-wise scaling and root planing was performed over four treatment sessions scheduled at one-week intervals using ultrasonic scalers and Gracey curettes. Standardized oral hygiene instructions were provided before treatment. Participants were re-evaluated at 1-, 3-, and 6-month follow-up visits, and additional non-surgical periodontal treatment was provided for sites requiring further therapy when clinically indicated. Clinical outcomes, patient-reported outcomes, and the environmental impact of the treatment protocol were assessed throughout the study.

Quadrant-Wise Scaling and Root Planing (Q-SRP)

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age ≥18 years. Diagnosis of Stage III periodontitis according to the 2017 World Workshop -Classification of Periodontal and Peri-Implant Diseases and Conditions.
• Presence of at least four teeth in each quadrant, including at least one molar, excluding third molars.
• Absence of any systemic disease. No regular use of systemic medications. No history of periodontal treatment within the previous 6 months. No use of antibiotics, anti-inflammatory agents, or any other medications that could affect periodontal tissues within the previous 6 months.
• Non-smokers or individuals who had ceased smoking for at least 1 year prior to enrollment.
• Not pregnant or breastfeeding.

You may not qualify if:

• Age \<18 years. Presence of any systemic disease. Regular use of systemic medications. History of periodontal treatment within the previous 6 months. Failure to complete the treatment protocol or attend scheduled follow-up visits.
• Current smoking. Use of antibiotics, anti-inflammatory agents, or any other medications that could affect the periodontal tissues within the previous 6 months.
• Requirement for antibiotic prophylaxis prior to dental treatment.

Sponsors & Collaborators

• Selcuk University: lead

Study Sites (1)

Selcuk University Faculty of Dentistry

Konya, 42060, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Periodontitis

Interventions

Root Planing

Condition Hierarchy (Ancestors)

Periodontal Diseases; Mouth Diseases; Stomatognathic Diseases

Intervention Hierarchy (Ancestors)

Dental Scaling; Dental Prophylaxis; Periodontics; Dentistry; Subgingival Curettage; Preventive Dentistry

Study Officials

• Sefa Aydındoğan

  Department of Periodontology, Faculty of Dentistry, Selcuk University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Research Assistant

Study Record Dates

• First Submitted: August 20, 2026
• First Posted: August 25, 2026
• Study Start: September 15, 2025
• Primary Completion: September 1, 2026
• Study Completion: September 1, 2026
• Last Updated: August 25, 2026

Record last verified: 2026-07

Locations

TU (1)