Treatment of Periodontitis by Tulsi Gel
Non Surgical Treatment Using Tulsi Gel Versus Chlorhexidine Gel as Adjunctive in Treatment of Advanced Periodontitis ( Stage III and Stage IV )
1 other identifier
interventional
24
1 country
1
Brief Summary
This study will be carried out to compare between the effect of 4%Tulsi gel and 1%Chlorohexidine gel as locally administered agents in the treatment of advanced periodontitis. Clinical parameters measurements, microbiological and radiographic assessment will be performed at base line, one month and 3 months after the intervention.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for phase_2
Started Jul 2025
Shorter than P25 for phase_2
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
November 4, 2024
CompletedFirst Posted
Study publicly available on registry
November 5, 2024
CompletedStudy Start
First participant enrolled
July 1, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 1, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
November 1, 2025
CompletedJuly 1, 2025
June 1, 2025
1 month
November 4, 2024
June 27, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (3)
Clinical parameters
Improvement of the clinical attachment loss in millimeters.
3 months after end of treatment
Clinical parameters
Improvement of gingival index.
3 months after end of treatment
Clinical parameters
Improvement of probing depth in millimeters.
3 months after end of treatment
Secondary Outcomes (3)
Microbiological assessment
3 months after end of treatment
Microbiological assessment
3 months after end of treatment
Microbiological assessment
3 months after end of treatment
Study Arms (2)
Tulsi Gel group
ACTIVE COMPARATOROcimum sanctum
Chlorhexidine Gel group
ACTIVE COMPARATORChlorhexidine
Interventions
After scaling and root debridement, 4% of Tulsi gel will be injected in to the sulcus until it over flooded, at base line, then after one month.
After scaling and root debridement, 1% of Chlorhexidine gel will be injected in to the sulcus until it over flooded, at base line, then after one month.
Eligibility Criteria
You may qualify if:
- All patients included in this study will be having advancedI Periodontitis
- Aging from 30 to 50 years old
- Free from any local or systemic risk factors that may affect the results of the study.
You may not qualify if:
- Long-term therapy with medications within a month prior to enrollment that could affect periodontal status or healing.
- Pregnant woman and lactating mothers.
- Patients with previous periodontal treatment including scaling and root planning and periodontal surgery in the last 3 and 6 months, respectively.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Faculty of Dentistry, Al-Azhar university
Cairo, Egypt
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- phase 2
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Dentist
Study Record Dates
First Submitted
November 4, 2024
First Posted
November 5, 2024
Study Start
July 1, 2025
Primary Completion
August 1, 2025
Study Completion
November 1, 2025
Last Updated
July 1, 2025
Record last verified: 2025-06