NCT07760194

Brief Summary

Evaluation of fetal cardiac functions in cases complicated with growth restriction

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
28

participants targeted

Target at below P25 for all trials

Timeline
1mo left

Started Aug 2026

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress40%
Aug 2026Sep 2026

Study Start

First participant enrolled

August 1, 2026

Completed
6 days until next milestone

First Submitted

Initial submission to the registry

August 7, 2026

Completed
5 days until next milestone

First Posted

Study publicly available on registry

August 12, 2026

Completed
20 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2026

Last Updated

August 12, 2026

Status Verified

August 1, 2026

Enrollment Period

1 month

First QC Date

August 7, 2026

Last Update Submit

August 7, 2026

Conditions

Fetal Growth Restriction

Keywords

Fetal heartEchocardiographyIUGR

Outcome Measures

Primary Outcomes (1)

  • Measurement of MPI

    Increased MPI means bad outcome

    2 weeks

Study Arms (2)

Cases with IUGR

Fetal weight less than 10th percentile

Procedure: Echocardiography

Cases with normal growth

Fetal weight between 10th and 90th percentile

Procedure: Echocardiography

Interventions

EchocardiographyPROCEDURE

Modified MPI is obtained by placing the Doppler sample volume on the medial wall of the ascending aorta including the AV and MV, hence the movements of both valves are recorded simultaneously in the Doppler spectrum through measurements of the isovolumetric contraction time (ICT), isovolumetric relaxation time (IRT) and ejection time (ET). The isovolumetric contraction time (ICT) was measured from the closure of the MV to the opening of the AV, the ejection time (ET) from the opening to the closure of the AV, and the isovolumetric relaxation time (IRT) from the closure of the AV to the opening of the MV. The MPI (Tei index) was calculated using the following equation: MPI= (ICT + IRT)/ET

Cases with IUGRCases with normal growth

Eligibility Criteria

Sexfemale
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Fetuses with IUGR will be included in group 1. Fetuses with normal growth will be included in group 2.

You may qualify if:

  • pregnant women
  • more than 28 weehs gestation

You may not qualify if:

  • intrauterine fetal death

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Women's Health Hospital

Asyut, Egypt

Location

MeSH Terms

Conditions

Fetal Growth Retardation

Condition Hierarchy (Ancestors)

Fetal DiseasesPregnancy ComplicationsFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesGrowth DisordersPathologic ProcessesPathological Conditions, Signs and Symptoms

Central Study Contacts

Mohamed Fekry

CONTACT

+20882312388mohamedbeethoven2040@gmail.com

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Lecturer of obstetrics and gynecology

Study Record Dates

First Submitted

August 7, 2026

First Posted

August 12, 2026

Study Start

August 1, 2026

Primary Completion (Estimated)

September 1, 2026

Study Completion (Estimated)

September 1, 2026

Last Updated

August 12, 2026

Record last verified: 2026-08

Locations

EG(1)