Medication Collaboration Feasibility Study

NCT07742189 | Recruiting

• 1 other identifier: STU00226320
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

This study examines the feasibility and acceptability of a brief medication collaboration intervention among older adults (age 60+) with early-stage dementia or mild cognitive impairment who take multiple medications and their family caregivers. The main aims are to: 1) determine the feasibility and acceptability of the intervention for older adults with early-stage dementia and their family caregivers, and 2) explore the effects of intervention on medication collaboration, medication adherence, and beliefs about dementia and autonomy. In this study, participants will: 1) complete a 15-30-minute baseline interview (by Zoom or phone), 2) participate together in a 45-60-minute virtual intervention led by an interventionist that includes: Assessment of medication responsibilities and beliefs. Education about dementia and medication management. Cognitive restructuring to address beliefs about independence and caregiver assistance. Collaborative planning for medication responsibilities and routines; and lastly 3) complete a 15-20-minute one-month follow-up interview (by Zoom or phone) to assess the intervention's acceptability and changes in medication management outcomes.

Conditions

Dementia Family Caregiver; Dementia; Medication Adherence

Outcome Measures

Primary Outcomes (1)

• Acceptability of the Medication Collaboration Intervention

  Participant-reported acceptability of the intervention will be measured using The Acceptability of Intervention Measure, Intervention Appropriateness Measure, and Feasibility of Intervention Measure. Scale values range from 1 to 5 with a higher score indicating greater perceived acceptability of the Medication Collaboration Intervention.

  1 Month

Secondary Outcomes (5)

• Medication Collaboration

  1 Month

• Medication adherence

  1 Month

• Beliefs about dementia

  1 month

• Medication Administration Hassles

  1 Month

• Beliefs about independence with medicines

  1 month

Study Arms (1)

Medication Collaboration Intervention

EXPERIMENTAL

Participants receive a brief virtual medication collaboration intervention designed to support collaborative medication management among older adults with early-stage dementia and their family caregivers. The intervention includes an assessment of medication responsibilities and beliefs, dementia and medication management education, reframing beliefs about autonomy and caregiver assistance, and collaborative development of medication management plans and action planning by setting implementation intentions.

Behavioral: Medication Collaboration Intervention

Interventions

Medication Collaboration Intervention BEHAVIORAL

A brief virtual behavioral intervention for older adults with early-stage dementia and their family caregivers designed to support collaborative medication management. The intervention includes: (1) assessment of beliefs about dementia, autonomy, and current medication responsibilities; (2) education on dementia progression and medication management; (3) reframing maladaptive beliefs regarding independence and caregiver assistance; and (4) collaborative development of implementation intentions and medication responsibility plans to facilitate medication adherence and the transition of medication management responsibilities. The intervention is delivered remotely via Zoom or telephone in a single 45-60-minute session by trained study interventionists.

Medication Collaboration Intervention

Eligibility Criteria

• Age: 60 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age 60 or older
• Diagnosis of dementia, Alzhimer's Disease or Mild Cognitive Impairment
• Quick Dementia Rating Scale Score 2-12 (inclusive of mild cognitive impairment and mild dementia)
• Taking 3 or more medications
• Involved with managing their medications
• Proficient speaking English
• Capacity to provide consent
• Primary family caregiver for the past 3 months
• Age 18 or older
• Proficient speaking English

You may not qualify if:

• adults unable to consent

Sponsors & Collaborators

• Northwestern University: lead

Study Sites (1)

Northwestern University

Chicago, Illinois, 60611, United States

RECRUITING

MeSH Terms

Conditions

Dementia; Medication Adherence

Condition Hierarchy (Ancestors)

Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Neurocognitive Disorders; Mental Disorders; Patient Compliance; Patient Acceptance of Health Care; Treatment Adherence and Compliance; Health Behavior; Behavior

Central Study Contacts

Rachel O'Conor

CONTACT

13125033240; r-oconor@northwestern.edu

Dianne Oladejo

CONTACT

3125036452; dianne.oladejo@northwestern.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: July 27, 2026
• First Posted: August 3, 2026
• Study Start: August 3, 2026
• Primary Completion (Estimated): December 1, 2026
• Study Completion (Estimated): December 1, 2026
• Last Updated: August 14, 2026

Record last verified: 2026-08

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)