Final Prototype Refinement of Adaptive Cell Phone Support
ACPS
Adaptive Cell Phone Support to Promote Medication Adherence Among Adolescents and Young Adults With Chronic Health Conditions
1 other identifier
interventional
35
1 country
1
Brief Summary
The goal of this feasibility pilot trial is to finalize the design of a mobile health intervention for promoting medication adherence in a population of adolescents and young adults with chronic health conditions. The main question\[s\] it aims to answer are:
- 1.Is the final version of the intervention sufficiently feasible, usable, and acceptable for evaluation in a randomized clinical trial?
- 2.Do participants show improvements in medication adherence during their field testing of the intervention?
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Mar 2026
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
July 17, 2025
CompletedFirst Posted
Study publicly available on registry
July 24, 2025
CompletedStudy Start
First participant enrolled
March 25, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 31, 2027
ExpectedStudy Completion
Last participant's last visit for all outcomes
January 31, 2027
May 12, 2026
May 1, 2026
10 months
July 17, 2025
May 8, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (3)
Total scores on the theoretical framework of acceptability questionnaire
Higher scores indicate a greater "extent to which people delivering or receiving a healthcare intervention consider it to be appropriate, based on anticipated or experienced cognitive and emotional responses to the intervention"; the minimum value of this questionnaire is 7 and the maximum value is 35.
Baseline to 3 weeks
Mean scores on the Mobile Health App Usability Questionnaire
Higher scores indicate greater ease with which users can use technology to achieve a particular goal; the minimum value of this questionnaire is 1 and the maximum value is 7.
Baseline to 3 weeks
Total scores on the Visual Analogue Scale
Percentage of doses taken our of 100%; higher numbers indicate greater medication adherence. This scale presents participants with a line, marked 0 on the left and 100 on the right, and participants can drag a marker to the place on the line that best visually indicated their adherence.
Baseline to 3 weeks
Study Arms (1)
Adaptive Cell Phone Support
EXPERIMENTALComputer-delivered cell phone support (reminders, problem-solving, referrals to resources) and responsive human coaching (phone calls, test messages, in-app messaging) to improve medication adherence.
Interventions
Mobile health adherence promotion based on the supportive accountability model
Eligibility Criteria
You may qualify if:
- Children's Hospital Los Angeles patient
- between 15-20 years old at enrollment
- taking at least one oral medication per day for a chronic health condition
- English speaking
- demonstrating sufficient cognitive capacity to engage in the assent/consent process and study procedures
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Children's Hospital Los Angeles
Los Angeles, California, 90027, United States
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Caitlin Sayegh, PhD
Children's Hospital Los Angeles
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- SUPPORTIVE CARE
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Assistant Professor of Clinical Pediatrics
Study Record Dates
First Submitted
July 17, 2025
First Posted
July 24, 2025
Study Start
March 25, 2026
Primary Completion (Estimated)
January 31, 2027
Study Completion (Estimated)
January 31, 2027
Last Updated
May 12, 2026
Record last verified: 2026-05
Data Sharing
- IPD Sharing
- Will share
- Time Frame
- Final submission and release of the study data will occur no later than the time of an associated publication or the end of the performance period, whichever comes first. Study data deposited in DASH will be available to the research community in perpetuity.
- Access Criteria
- https://dash.nichd.nih.gov/resource/DASHUserAgreement
The data will include electronically-administered survey items assessing demographic characteristics, intervention usability, intervention acceptability, medication adherence, motivation for adherence, transition readiness skills, and allocation of treatment responsibility as well as medication regimen complexity data and pharmacy possession refill rates abstracted from the electronic medical chart, and behavioral engagement data collected via the Computerized Intervention Authoring Software.