Comparative Effects of Task-Oriented Training and Hand-Arm Bimanual Intensive in Post-Stroke Patients

NCT07724925 | Recruiting DMC

• 1 other identifier: REC/RCR & AHS/25/0238
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

Stroke is a rapidly developing clinical signs of focal (or global) disturbance of cerebral function, lasting more than 24 hours or leading to death, with no apparent cause other than a vascular origin. Among various rehabilitation strategies, Task-oriented training of low to moderate intensity and Hand-Arm bimanual intensive therapy have shown their promising results in stroke rehabilitation. So, this study aims to determine the comparative effects of Task-oriented and Hand-Arm bimanual intensive therapy on Gross and Fine motor skills of Upper Limb and Activities of Daily Living in Post-Stroke Patients.

Conditions

Stroke

Keywords

Task-Oriented Training; Hand-Arm Bimanual Intensive Therapy; Gross and Fine Motor Skills; Activities of Daily Living

Outcome Measures

Primary Outcomes (3)

• Gross Motor Skills

  Action Research Arm Test

  Baseline and post 8 weeks

• Fine Motor Skills

  Nine Hole Peg Test

  Baseline and post 8 weeks

• Activities of Daily Living

  Barthel Index Scale

  Baseline and post 8 weeks

Study Arms (2)

GROUP A: TOT

EXPERIMENTAL

Frequency: 3 session/week for 8 weeks Intensity: 5 reps/session Duration: 30 minutes, increasing to 45 minutes by the end of week 8 Exercises: * Reaching * Push-pull tasks * Grasping * Wiping tasks * Weight-bearing on hands * Lifting an object (2 sets×5 reps of each exercise) Gradually increasing duration and intensity each week.

Other: Task-Oriented Training

GROUP B: HABIT

ACTIVE COMPARATOR

Frequency: 3 session/week for 8 weeks Intensity: 5 reps/session Duration:30 minutes, increasing to 45 minutes by the end of week 8 Exercises: * Rolling a ball * Opening containers * Towel folding * Lifting and placing objects * Cutting with scissors * Zipping and buttoning * Peeling fruits (2 sets×5 reps of each exercise) Gradually increasing duration and intensity each week.

Other: Hand-Arm Bimanual Intensive Therapy

Interventions

Task-Oriented Training OTHER

Frequency: 3 session/week for 8 weeks Intensity: 5 reps/session Duration: 30 minutes, increasing to 45 minutes by the end of week 8 Exercises: * Reaching * Push-pull tasks * Grasping * Wiping tasks * Weight-bearing on hands * Lifting an object (2 sets×5 reps of each exercise) Gradually increasing duration and intensity each week.

GROUP A: TOT

Hand-Arm Bimanual Intensive Therapy OTHER

Frequency: 3 session/week for 8 weeks Intensity: 5 reps/session Duration:30 minutes, increasing to 45 minutes by the end of week 8 Exercises: * Rolling a ball * Opening containers * Towel folding * Lifting and placing objects * Cutting with scissors * Zipping and buttoning * Peeling fruits (2 sets×5 reps of each exercise) Gradually increasing duration and intensity each week.

GROUP B: HABIT

Eligibility Criteria

• Age: 45 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age 45-70
• Gender (both male and female)
• Pre diagnosed First-time stroke patients (ischemic or hemorrhagic)
• Time since stroke: ≥3 months
• Mild to moderate upper limb impairment (ABILHAND Questionnaire: Less than 50% of items rated as "impossible.")
• Moderate functional independence in basic activities (Barthel Index score ≥ 60)
• Ability to follow commands (MMSE \> 24 or equivalent cognitive screening)

You may not qualify if:

• Severe spasticity (Modified Ashworth Scale score ≥ 3) or contractures
• Other neurological conditions (Alzheimer's disease, Parkinson and dementia)
• Unstable medical conditions (diabetes and hypertension) that may interfere with participation
• Participation in any other structured upper limb rehabilitation or experimental therapy within the past 3 months

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

DHQ Hospital Nankana Sahib

Nankana Sahib, Pakistan

RECRUITING

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Aiza Yousaf, MS-OMPT

  Riphah International University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Imran Amjad, PhD

CONTACT

03324390125; imran.amjad@riphah.edu.pk

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Masking Details: An independent assessor, who is blinded to the group allocations, will be responsible for evaluating outcomes.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: randomized clinical trial

Study Record Dates

• First Submitted: July 21, 2026
• First Posted: July 24, 2026
• Study Start: June 1, 2025
• Primary Completion: July 30, 2026
• Study Completion (Estimated): August 2, 2026
• Last Updated: July 24, 2026

Record last verified: 2026-07

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)