Comparative Effects of Task Oriented Progressive Resistance Training and Modified Otago Exercise Among Stroke Patients.

NCT07578948 | Active Not Recruiting

• 1 other identifier: REC/RCR&AHS/25/0214
• Study Type: interventional
• Target: 52
• Locations: 1 country
• Sites: 1

Brief Summary

Comparative Effects of Task Oriented Progressive Resistance Training and Modified Otago Exercise on Balance and Lower Limb Motor Function Among Stroke Patients.

Conditions

Stroke

Keywords

Balance; Motor function; Modified otago exercises; Task oriented progressive resistance training

Outcome Measures

Primary Outcomes (3)

• Fugl-Meyer Assessment (FMA)

  Fugl-Meyer Assessment of Lower Extremity (FMA-LE) total score interpretation ranges from 0 to 34, with higher scores indicating better motor function. Generally, a score of 34 represents normal function, while scores below 29 indicate varying degrees of disability. (15) All FMA-LE forms and subscales showed a high internal consistency (Cronbach's alpha\>0.91).

  baseline to 4rth week

• Berg Balance Scale (BBS)

  The BBS is postural balance scale containing 14 items including standing and sitting unsupported, reaching forward, and placing the alternating foot on a stool. Administering the BBS takes approximately 15 min. Each of the 14 items are scored on a 5-level ordinal scale from 0 (-unable to perform or requiring help‖) to 4 (-normal performance‖), thus providing a potential maximum score of 56 points. (13) test-retest (ICC = 0.96; 95% CI, 0.93-0.98) and inter-rater (ICC = 0.93; 95% CI, 0.87-0.97) reliability was excellent

  Baseline to 4rth week

• Mini Mentel Scale (MMS)

  The Mini-Mental State Examination (MMSE) is a brief test used to screen for cognitive impairment, particularly in older adults. It assesses different aspects of cognitive function, including orientation, attention, memory, and language. The MMSE is scored on a scale of 0-30, with a score of 24 or higher generally considered normal. (17) The Mini-Mental State Examination (MMSE) generally demonstrates good internal consistency reliability, as indicated by Cronbach's alpha values ranging from 0.78 to 0.81.

  baseline to 4rth week

Study Arms (2)

Modified otago exercises

EXPERIMENTAL

Other: Modified otago exercise

Task oriented progressive resistance training

ACTIVE COMPARATOR

Participants receive interventions 3 session per week for 4 weeks

Other: Task oriented progressive resistance training

Interventions

Modified otago exercise OTHER

Warm up Head, neck, back extension, trunk, and ankle movement * Muscle strengthening: * Front knee (3) * Back knee * Side hip * Calf raises * Toe rises * Balance training: * Knee bends * Backward walking * Walk and turn * Sideways walk * Heel toe stand * Heel toe walk * One leg stand * Heel walk * Toe walk * Heel toe backward walk * Sit to stand * Stair walk

Also known as: MOE

Modified otago exercises

Task oriented progressive resistance training OTHER

Standing and reaching in different directions for objects beyond arm's length * Sit to stand from various chair heights to strengthen lower limb extensors (3) * Stepping forward and backward on blocks of various heights * Stepping sideways on blocks of various heights * Forward stepping on blocks of various heights * Heel raise and lower in standing to strengthen plantar flexors (3)

Task oriented progressive resistance training

Eligibility Criteria

• Age: 45 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adults aged 45 to 65 years. (9)
• Both genders male and female.
• Clinically diagnosed with ischemic stroke.
• Chronic stroke patients 6 to 10 months.
• Presence of hemiparesis with mild to moderate motor deficits FMA-LE score 34.
• Cognitive impairment MMSE score more than 26.
• Ability to walk at least 10 meters with or without an assistive device

You may not qualify if:

• Dementia or major neurocognitive disorder. (6)
• Complete paralysis or unable to participate in active exercise. (11)
• Patients with severe joint pain or arthritis are excluded due to reduce risk of injury and avoid confounding factors.
• Recent fractures, or other musculoskeletal issues limiting exercise participation.
• Suffering from physical diseases that prevent full participation in training.

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

Unknown Facility

Lahore, Punjab Province, 54000, Pakistan

Location

Related Publications (3)

• Cekmece C, Sade I, Ozcan E, Balci S. Investigation of the effect of task-oriented occupational therapy on daily living activity performance in chronic stroke patients. Pak J Med Sci. 2024 Jul;40(6):1214-1218. doi: 10.12669/pjms.40.6.7954.

  PMID: 38952526 BACKGROUND

• Appelros P, Stegmayr B, Terent A. Sex differences in stroke epidemiology: a systematic review. Stroke. 2009 Apr;40(4):1082-90. doi: 10.1161/STROKEAHA.108.540781. Epub 2009 Feb 10.

  PMID: 19211488 BACKGROUND

• Murphy SJ, Werring DJ. Stroke: causes and clinical features. Medicine (Abingdon). 2020 Sep;48(9):561-566. doi: 10.1016/j.mpmed.2020.06.002. Epub 2020 Aug 6.

  PMID: 32837228 BACKGROUND

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Sabiha Arshad, Ms

  Riphah International University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 5, 2026
• First Posted: May 11, 2026
• Study Start: April 5, 2025
• Primary Completion (Estimated): June 3, 2026
• Study Completion (Estimated): July 6, 2026
• Last Updated: May 11, 2026

Record last verified: 2026-05

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)