Clinical Performance of Different Ion-Releasing Restorative Systems in Class II Cavities
ION-REST II
Two-Year Clinical Performance of Different Ion-Releasing Restorative Systems Applied in Class II Cavities
1 other identifier
interventional
40
1 country
1
Brief Summary
Different ion-releasing restorative systems will be applied in class II cavities then their clinical performance will be evaluated and compared
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Jun 2025
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 1, 2025
CompletedFirst Submitted
Initial submission to the registry
June 30, 2026
CompletedFirst Posted
Study publicly available on registry
July 7, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2027
ExpectedStudy Completion
Last participant's last visit for all outcomes
July 1, 2027
July 9, 2026
May 1, 2026
2 years
June 30, 2026
July 7, 2026
Conditions
Outcome Measures
Primary Outcomes (1)
difference between baseline and after two years of evaluation
Changes in restoration performance according to the modified Federation Dentaire Internationale (FDI) criteria from baseline to 2 years. Scores range from 1 to 5, where lower scores indicate better clinical performance and higher scores indicate poorer clinical performance.
baseline to two-years
Study Arms (4)
conventional bulk fill restorative system
EXPERIMENTALposterior cavities restored with conventional bulk fill restorative system applied in single increment according to the manufacturer's instructions
ion- releasing restorative system 1
EXPERIMENTALposterior cavities restored with ion-releasing restorative system applied 1 in single increment according to the manufacturer's instructions
ion-releasing restorative system 2
EXPERIMENTALposterior cavities restored with ion-releasing restorative system 2 applied in single increment according to the manufacturer's instructions
ion-releasing restorative system 3
EXPERIMENTALposterior cavities restored with ion-releasing restorative system 3 applied in single increment according to the manufacturer's instructions
Interventions
conventional bulk fill restorative system used for posterior applications
ion-releasing restorative system 1 used for posterior applications
ion-releasing restorative system 2 used for posterior applications
ion-releasing restorative system 3 used for posterior applications
Eligibility Criteria
You may qualify if:
- at least 4 carious posterior teeth
You may not qualify if:
- pregnancy - not able to attend for regular follow-up -smokers or very bad oral hygiene
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Faculty of Dentistry, Mansoura University
Al Mansurah, Dakahlia Governorate, 35516, Egypt
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Asmaa A Elbanna, Assistant Lecturer
Faculty of Dentistry, Mansoura University
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, INVESTIGATOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
June 30, 2026
First Posted
July 7, 2026
Study Start
June 1, 2025
Primary Completion (Estimated)
June 1, 2027
Study Completion (Estimated)
July 1, 2027
Last Updated
July 9, 2026
Record last verified: 2026-05
Data Sharing
- IPD Sharing
- Will share
- Shared Documents
- STUDY PROTOCOL, SAP
- Time Frame
- Data will be available after two years
- Access Criteria
- anyone
study protocol and statistical analysis will be shared to other researchers