NCT07654153

Brief Summary

The aim of this study is to prospectively evaluate the effect of surgical position on the development of postoperative atelectasis in patients undergoing surgery in supine, prone, lateral decubitus, and lithotomy positions using lung ultrasonography (LUS), and to investigate whether there is a difference between these positions.

Trial Health

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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
13mo left

Started Jul 2026

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 12, 2026

Completed
5 days until next milestone

First Posted

Study publicly available on registry

June 17, 2026

Completed
1 month until next milestone

Study Start

First participant enrolled

July 20, 2026

Expected
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 20, 2027

1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2027

Last Updated

June 17, 2026

Status Verified

June 1, 2026

Enrollment Period

11 months

First QC Date

June 12, 2026

Last Update Submit

June 12, 2026

Conditions

Keywords

lung ultrasound

Outcome Measures

Primary Outcomes (1)

  • Modified Lung Ultrasound Score

    MLUS Scoring: Each region will be scored between 0-3 according to lung ventilation (MLUS Score): * 0 Points: Normal ventilation (presence of A-line, fewer than 3 B-lines) * 1 Point: Minor ventilation loss (≥ 3 B-lines or subpleural consolidations ≤ 1 cm in diameter separated by a normal pleural line) * 2 Points: Moderate ventilation loss (Multiple small subpleural consolidations ≤ 1 cm in diameter separated by multiple and converging B-lines or a thickened/irregular pleural line) * 3 Points: Severe ventilation loss (At least one consolidation \> 1 cm in diameter or subpleural consolidations \> 1x2 cm in diameter) The total MLUS score will be obtained by summing the scores of the 12 regions (Minimum 0, Maximum 36). Atelectasis will be defined as "predisposition to atelectasis when each quadrant score is 2 or 3".

    The assessment will be performed at 3 different time points: 1. Preoperative (T0): Immediately before anesthesia induction, in the supine position (Baseline). 2. Postoperative 1st hour (T1): Immediately before the patient is awakened, in the supine posit

Study Arms (4)

Group 1

Supine position

Procedure: lung ultrasound

group 2

prone position

Procedure: lung ultrasound

group 3

lateral decubitus

Procedure: lung ultrasound

Group 4

lithotomy

Procedure: lung ultrasound

Interventions

Lung Ultrasound (LUS) Protocol: The LUS evaluation will be performed by Dr. Burak Ağar using a Mindray ultrasound device \[Device brand/model and probe type, e.g., 3.5-5 MHz convex or 7-12 MHz linear probe\]

Group 1Group 4group 2group 3

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

The study will include a total of 100 patients in 4 groups, aged 18-65 years, with an ASA (American Society of Anesthesiologists) physical status between I and III, who are scheduled to undergo general anesthesia in supine, prone, lateral decubitus, and lithotomy positions.

You may qualify if:

  • Being between 18-65 years of age
  • Having ASA I-III status
  • Planning elective surgery under general anesthesia
  • Agreeing to participate in the study and signing the consent form

You may not qualify if:

  • Patients requiring emergency surgery
  • Patients with ASA IV or higher
  • Presence of a known serious preoperative lung disease (COPD, Asthma, Pneumonia, Pleural effusion, Pneumothorax, Interstitial lung disease, Bronchiectasis, etc.)
  • History of neuromuscular disease
  • Body Mass Index (BMI) \> 35 kg/m² (Morbid obesity)
  • Presence of chest wall deformity or skin lesions that would obstruct LUS imaging
  • Cases with surgery duration \< 90 minutes
  • Patients with alcohol or drug dependence
  • Patients with significant anemia
  • Pregnant and lactating patients
  • Patients experiencing laryngospasm after extubation
  • Refusal to give consent or inability to cooperate

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Sivas Cumhuriyet University

Sivas, Sivas, 58140, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Pulmonary Atelectasis

Condition Hierarchy (Ancestors)

Lung DiseasesRespiratory Tract Diseases

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

June 12, 2026

First Posted

June 17, 2026

Study Start (Estimated)

July 20, 2026

Primary Completion (Estimated)

June 20, 2027

Study Completion (Estimated)

August 1, 2027

Last Updated

June 17, 2026

Record last verified: 2026-06

Data Sharing

IPD Sharing
Will not share

Locations