Evaluation of the Effects of Different Ventilation Modes Used During Anesthesia Awakening on the Frequency of Postoperative Atelectasis

NCT06358027 | Not Yet Recruiting

• 1 other identifier: DokuzEU-ACC-BOtlu-01
• Study Type: observational
• Target: 278
• Locations: 0 countries
• Sites: N/A

Brief Summary

In our study, we aimed to detect atelectasis developing in patients undergoing surgery under general anesthesia using transthoracic lung ultrasonography and to investigate the effect of ventilation methods used during recovery from anesthesia on the formation of postoperative atelectasis.

Conditions

Atelectasis, Postoperative Pulmonary

Keywords

Lung Ultrasonography; Atelectasis; Postoperative Pulmonary Complications; Pressure Support Ventilation

Outcome Measures

Primary Outcomes (1)

• Modified Transthoracic Ultrasound Score

  Both lungs were determined as anterior and posterior axillary lines as anatomical markers and divided into a total of 12 regions, 4 in the anterior thoracic wall, 4 in the lateral wall, and 4 in the posterior region. While the anterior and lateral regions were examined in the supine position by placing the probe perpendicular to the thoracic wall and longitudinal in the intercostal spaces with the bat sign displayed, especially the posterior regions close to the diaphragm were examined by placing the probe transversely in the intercostal spaces by turning the patient opposite. According to the systematic LUS protocol, each patient was evaluated for approximately 10-15 minutes and optimum images were obtained.Each area was scored on a scale of 0-3 according to the degree of atelectasis, and a total score between 0 (normal lung ventilation image) and 36 (total loss of ventilation) was calculated.

  two weeks

Study Arms (2)

pressure support ventilation group

when the patients were ready for extubation, anesthesia was terminated by one of the selected pressure support ventilation

Diagnostic Test: lung ultrasound

manual ventilation group

when the patients were ready for extubation, anesthesia was terminated by one of the selected manual ventilation wake-up methods at the initiative of the relevant anesthesiologist.

Diagnostic Test: lung ultrasound

Interventions

lung ultrasound DIAGNOSTIC_TEST

The patients included in the study underwent lung imaging with lung ultrasound score twice, in the preoperative preparation room and in the postoperative recovery unit.Both lungs were determined as anterior and posterior axillary lines as anatomical markers and divided into a total of 12 regions, 4 in the anterior thoracic wall, 4 in the lateral wall, and 4 in the posterior region. In our study, we will use the modified LUS scoring, which has been shown to be more sensitive in the diagnosis of postoperative atelectasis in the recovery unit, based on existing literature reviews. The degree of the atelectasis will be determined according to do modified lung ultrasound score. Lung ultrasound score imaging of all patients was performed by the same anesthesiologist.

Also known as: Modified Transthoracic Ultrasound Scoring System

manual ventilation group; pressure support ventilation group

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The patients 18 years of age or older and American Society of Anesthesiologists (ASA) physical status I and III who were scheduled for general anesthesia were included in this prospective observational study.

You may qualify if:

• Patients undergoing general anesthesia with supine position
• Endotracheal intubations and mechanical ventilation during general anesthesia
• Operation time is more than 2 hours

You may not qualify if:

• Patients who will undergo surgical intervention under emergency conditions
• Pregnancy
• Upper respiratory tract disease in the last 3 weeks
• Previous lung surgery
• Advanced cardiac and/or pleural lung disease and chest wall deformity, and primary or metastatic lung cancer

Sponsors & Collaborators

• Dokuz Eylul University: lead

MeSH Terms

Conditions

Pulmonary Atelectasis

Condition Hierarchy (Ancestors)

Lung Diseases; Respiratory Tract Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant professor

Study Record Dates

• First Submitted: April 5, 2024
• First Posted: April 10, 2024
• Study Start: April 5, 2024
• Primary Completion: April 21, 2024
• Study Completion: April 30, 2024
• Last Updated: April 10, 2024

Record last verified: 2024-04

Data Sharing

• IPD Sharing: Will not share