Correlation Study Between Cervical Vertebrae Volume and Skeletal Maturational Stage in Egyptian Females

NCT07653542 | Completed DMC

• 1 other identifier: 8888
• Study Type: observational
• Target: 131
• Locations: 1 country
• Sites: 1

Brief Summary

Correlation between cervical vertebrae volume with maturational stage through CBCT

Conditions

Cervical Vertebrae

Keywords

cervical vertebrae; skeletal maturation; vertebral volume; CBCT segmentation

Outcome Measures

Primary Outcomes (1)

• clinical correlation between cervical vertebrae volume and patient's maturational stage

  the data (volume of cervical vertebrae C2, C3 and C4) is collected from the CBCT of the patient on the day of arrival of the radiograph

  Data is collected on Day 1 No follow up is needed because it is an observational

Study Arms (1)

CBCT radiograph for Female Egyptian

Radiation: CBCT

Interventions

CBCT RADIATION

CBCT Radiographs of Egyptian Female patients will be selected from the patients' database at the Faculty of Dentistry, Cairo University. The CBCT Radiographs data will be reconstructed using 3D imaging software (3D Slicer ). The body of the 2nd, 3rd, and 4th vertebra will be cropped and other structures will be deleted. Each vertebra will be isolated using split mask tool, then 3D format of each vertebra will be obtained, and its 3D volume in mm³ will be recorded using 3D object properties. then evaluate the association between cervical vertebrae volume and maturation stages assessed using the CVM I

CBCT radiograph for Female Egyptian

Eligibility Criteria

• Age: 10 Years - 25 Years
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Probability Sample

Study Population

CBCT Radiographs of Egyptian Female patients

You may qualify if:

• CBCT Radiographs should have the following criteria :
• Female patients, age range from 10-25 years .
• Patients free of any serious illness.
• Patients with no cleft lip or palate.
• Patients with no previous trauma or injury in the head and neck region.

You may not qualify if:

• Patients suffering from congenital or acquired malformations affecting cervical vertebrae.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Faculty of Dentistry- Cairo university

Cairo, 12311, Egypt

Location

Related Publications (6)

• Gabriel DB, Southard KA, Qian F, Marshall SD, Franciscus RG, Southard TE. Cervical vertebrae maturation method: poor reproducibility. Am J Orthod Dentofacial Orthop. 2009 Oct;136(4):478.e1-7; discussion 478-80. doi: 10.1016/j.ajodo.2007.08.028.

  PMID: 19815136 RESULT

• Baccetti T, Franchi L, McNamara JA Jr. An improved version of the cervical vertebral maturation (CVM) method for the assessment of mandibular growth. Angle Orthod. 2002 Aug;72(4):316-23. doi: 10.1043/0003-3219(2002)0722.0.CO;2.

  PMID: 12169031 RESULT

• Franchi L, Baccetti T, McNamara JA Jr. Mandibular growth as related to cervical vertebral maturation and body height. Am J Orthod Dentofacial Orthop. 2000 Sep;118(3):335-40. doi: 10.1067/mod.2000.107009.

  PMID: 10982936 RESULT

• San Roman P, Palma JC, Oteo MD, Nevado E. Skeletal maturation determined by cervical vertebrae development. Eur J Orthod. 2002 Jun;24(3):303-11. doi: 10.1093/ejo/24.3.303.

  PMID: 12143094 RESULT

• Hunter CJ. The correlation of facial growth with body height and skeletal maturation at adolescence. Angle Orthod. 1966 Jan;36(1):44-54. doi: 10.1043/0003-3219(1966)0362.0.CO;2. No abstract available.

  PMID: 5218761 RESULT

• Hagg U, Taranger J. Maturation indicators and the pubertal growth spurt. Am J Orthod. 1982 Oct;82(4):299-309. doi: 10.1016/0002-9416(82)90464-x.

  PMID: 6961802 RESULT

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Maters degree candidate

Study Record Dates

• First Submitted: May 14, 2026
• First Posted: June 17, 2026
• Study Start: July 1, 2024
• Primary Completion: October 1, 2025
• Study Completion: January 1, 2026
• Last Updated: June 17, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)