Age Estimation From Pulp Cavity Analysis Using Cone Beam Computed Tomographic Images for Forensic Purposes

NCT05130164 | Unknown

• 1 other identifier: Christine Atef ORAD 7-1-1
• Study Type: observational
• Target: 25
• Locations: 1 country
• Sites: 1

Brief Summary

Forensic odontology is a branch of forensic science that utilizes a dentist's expertise in identification of individuals for whom traditional methods of identification aren't accessible due to a lack of common identification features. Medico-legal issues, natural catastrophes such as tsunamis, earthquakes, and explosions, death verification in monetary concerns, religious and social reasons are all examples of situations that require identification. Age, stature, sex and ethnicity are the "big four" determinants of personal identification. Dental age estimation has the benefit of that teeth are less influenced by external physical, chemical, or mechanical variables than other portions of the skeleton. Secondary dentin deposition in human teeth progresses with age that results in reduction in the size of the tooth pulp cavity which can be assessed as an age indicator. A significant relationship between pulp width and age was originally discovered in a study by Kvaal et al., 1995 who created regression formulae for age prediction using periapical radiograph by measuring of pulp size. Also, the assessment of pulp/tooth volume ratio relying on the gradual reduction in pulp volume produced by continuous apposition of dentin during life is one well-known dental age estimation approach. Cone beam computed tomography (CBCT) provides accurate three-dimensional images of the maxillofacial area. In addition, CBCT may be beneficial in some forensic situations, as it has massive benefits for post-mortem forensic imaging, as it offers skeletal imaging with high resolution, cheap cost, simplicity and portability. CBCT can be used in forensic age assessment since it is non-invasive and allows for the reconstruction of images in multiple planes to display anatomical and imaged elements in distinct planes. Our hypothesis is that pulp space analysis is totally different between different ages and that there is a correlation between age and pulp space analysis that could be of a forensic significance for age estimation in the investigated population.

Conditions

Healthy

Keywords

CBCT; Forensic dentistry; Age determination by teeth

Outcome Measures

Primary Outcomes (1)

• Pulp/ tooth volume ratio CBCT age to be correlated with chronological age

  Pulp/ tooth volume ratio CBCT age to be correlated with chronological age using volumetric segmentation of CBCT software in mm3.

  Through study completion, an average of 1 year

Secondary Outcomes (1)

• Analysis of pulp size using linear measurements.

  Through study completion, an average of 1 year

Study Arms (1)

Single group

Single group will be selected for age estimation using CBCT Scans

Radiation: CBCT

Interventions

CBCT RADIATION

Cone beam computed tomographic images selected for age estimation

Single group

Eligibility Criteria

• Age: 20 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

CBCT scans that meet the eligibility criteria for age estimation

You may qualify if:

• CBCT scans for male and female Egyptians between the ages of 20 and 60 years.
• CBCT scans with the required complement of teeth.

You may not qualify if:

• CBCT scans that lack a proof of age or date of birth.
• CBCT scans with the required teeth showing pathological processes in the apical bone.
• CBCT scans with overlying teeth.
• CBCT scans in which the required teeth were filled, prosthetically restored or carious.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Faculty of Dentistry, Cairo university

Cairo, Egypt

RECRUITING

Related Publications (1)

• Asif MK, Nambiar P, Mani SA, Ibrahim NB, Khan IM, Lokman NB. Dental age estimation in Malaysian adults based on volumetric analysis of pulp/tooth ratio using CBCT data. Leg Med (Tokyo). 2019 Feb;36:50-58. doi: 10.1016/j.legalmed.2018.10.005. Epub 2018 Oct 21.

  PMID: 30415192 RESULT

Study Officials

• Christine Beshara

  Cairo University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Christine Beshara

CONTACT

+201273539853; christine.beshara@dentistry.cu.edu.eg

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator & PhD student

Study Record Dates

• First Submitted: November 8, 2021
• First Posted: November 22, 2021
• Study Start: April 2, 2022
• Primary Completion: November 1, 2022
• Study Completion: December 1, 2022
• Last Updated: August 30, 2022

Record last verified: 2022-08

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)