NCT07641400

Brief Summary

The aim of this study is to determine the usability of echocardiographic PAP changes obtained from emergency department records in the early risk stratification of pulmonary embolism.

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
80

participants targeted

Target at P50-P75 for all trials

Timeline
4mo left

Started Jun 2026

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress12%
Jun 2026Oct 2026

First Submitted

Initial submission to the registry

June 1, 2026

Completed
Same day until next milestone

Study Start

First participant enrolled

June 1, 2026

Completed
10 days until next milestone

First Posted

Study publicly available on registry

June 11, 2026

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2026

Expected
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2026

Last Updated

June 11, 2026

Status Verified

June 1, 2026

Enrollment Period

3 months

First QC Date

June 1, 2026

Last Update Submit

June 6, 2026

Conditions

Keywords

emergency deparment patientspulmonary hypertensionpulmonary embolismdispneachest pain

Outcome Measures

Primary Outcomes (1)

  • pulmonary artery pressure

    The difference between the pulmonary artery pressure measured in the previous echocardiogram and the pulmonary artery pressure at the time of admission to the emergency department.

    3 hours

Secondary Outcomes (1)

  • the relationship between pulmonary embolism and comorbidity

    3 hours

Study Arms (2)

Pulmonary embolism (+)

Other: Pulmonary embolism (+)

Pulmonary embolism (-)

Other: pulmonary embolism (-)

Interventions

control group

Pulmonary embolism (-)

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients aged 18 and over who present to the emergency department with dyspnea between the specified study dates, are diagnosed with pulmonary embolism, have had their pulmonary artery pressure measured, have a previous pulmonary artery pressure measurement in their patient records, and have complete clinical, laboratory, imaging, and echocardiography data will be included in the study.

You may qualify if:

  • Presenting to the emergency department with dyspnea between the specified dates,
  • Being 18 years of age or older,
  • Being evaluated in the emergency department with a preliminary diagnosis of pulmonary embolism,
  • Having a recorded pulmonary artery pressure measurement at the time of hospital admission,
  • Having a previous pulmonary artery pressure measurement in the patient's records,
  • Having sufficient and complete clinical, laboratory, imaging, and echocardiography data available for the study.

You may not qualify if:

  • Patients under 18 years of age,
  • Lack of pulmonary artery pressure data from the time of emergency admission or from the previous period,
  • Lack of necessary clinical, laboratory, or imaging data for pulmonary embolism evaluation,
  • In cases of repeated admissions for the same patient, only the first suitable admission will be considered; other admissions will be excluded from the study,

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Health Sciences, Antalya Training and Research Hospital

Antalya, Turkey (Türkiye)

Location

Related Publications (1)

  • Cao YQ, Dong LX, Cao J. Pulmonary Embolism in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease. Chin Med J (Engl). 2018 Jul 20;131(14):1732-1737. doi: 10.4103/0366-6999.235865.

MeSH Terms

Conditions

Hypertension, PulmonaryPulmonary EmbolismChest Pain

Condition Hierarchy (Ancestors)

Lung DiseasesRespiratory Tract DiseasesHypertensionVascular DiseasesCardiovascular DiseasesEmbolismEmbolism and ThrombosisPainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • MURAT DUYAN, ASSOCIATE PROFESSOR

    University of Health Sciences, Antalya Training and Research Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

MURAT DUYAN, ASSOCIATE PROFESSOR

CONTACT

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 1, 2026

First Posted

June 11, 2026

Study Start

June 1, 2026

Primary Completion (Estimated)

September 1, 2026

Study Completion (Estimated)

October 1, 2026

Last Updated

June 11, 2026

Record last verified: 2026-06

Data Sharing

IPD Sharing
Will not share

Locations