NCT07647497

Brief Summary

This observational study evaluates right ventricular dysfunction in patients with acute pulmonary embolism using transthoracic echocardiography and assesses its prognostic significance and risk stratification value.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
112

participants targeted

Target at P50-P75 for all trials

Timeline
6mo left

Started Jun 2026

Shorter than P25 for all trials

Geographic Reach
1 country

2 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress8%
Jun 2026Nov 2026

First Submitted

Initial submission to the registry

May 23, 2026

Completed
9 days until next milestone

Study Start

First participant enrolled

June 1, 2026

Completed
14 days until next milestone

First Posted

Study publicly available on registry

June 15, 2026

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 30, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 30, 2026

Last Updated

June 15, 2026

Status Verified

June 1, 2026

Enrollment Period

6 months

First QC Date

May 23, 2026

Last Update Submit

June 10, 2026

Conditions

Keywords

Right Ventricular DysfunctionEchocardiographyPulmonary EmbolismRisk Stratification

Outcome Measures

Primary Outcomes (1)

  • Right ventricular dysfunction as a prognostic marker in acute pulmonary embolism

    To assess the prognostic value of right ventricular dysfunction detected by transthoracic echocardiography for risk stratification in patients with acute pulmonary embolism

    From hospital admission until hospital discharge, with an average duration of 7 days.

Secondary Outcomes (1)

  • In-hospital adverse clinical outcomes

    From hospital admission until hospital discharge, with an average duration of 7 days.

Study Arms (1)

Patients with acute pulmonary embolism

Patients diagnosed with acute pulmonary embolism who undergo transthoracic echocardiographic assessment for evaluation of right ventricular dysfunction.

Other: Transthoracic Echocardiography

Interventions

Transthoracic echocardiography performed for assessment of right ventricular dysfunction in patients with acute pulmonary embolism.

Patients with acute pulmonary embolism

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients diagnosed as acute pulmonary embolism

You may qualify if:

  • Patients aged 18 years and older.
  • Patients with a confirmed diagnosis of acute pulmonary embolism.
  • Patients who underwent transthoracic echocardiographic assessment for right ventricular dysfunction.

You may not qualify if:

  • Patients younger than 18 years.
  • Patients with incomplete clinical data.
  • Patients who did not undergo transthoracic echocardiography.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Sohag University hospital

Sohag, Egypt

NOT YET RECRUITING

Sohag University hospital

Sohag, Egypt

RECRUITING

Related Publications (1)

  • Konstantinides SV, Meyer G, Becattini C, Bueno H, Geersing GJ, Harjola VP, Huisman MV, Humbert M, Jennings CS, Jimenez D, Kucher N, Lang IM, Lankeit M, Lorusso R, Mazzolai L, Meneveau N, Ni Ainle F, Prandoni P, Pruszczyk P, Righini M, Torbicki A, Van Belle E, Zamorano JL; ESC Scientific Document Group. 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS). Eur Heart J. 2020 Jan 21;41(4):543-603. doi: 10.1093/eurheartj/ehz405. No abstract available.

    PMID: 31504429BACKGROUND

MeSH Terms

Conditions

Pulmonary EmbolismVentricular Dysfunction, Right

Condition Hierarchy (Ancestors)

Lung DiseasesRespiratory Tract DiseasesEmbolismEmbolism and ThrombosisVascular DiseasesCardiovascular DiseasesVentricular DysfunctionHeart Diseases

Central Study Contacts

Safiya Khalaf Abdallah, Assistant lecturer

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant lecture

Study Record Dates

First Submitted

May 23, 2026

First Posted

June 15, 2026

Study Start

June 1, 2026

Primary Completion (Estimated)

November 30, 2026

Study Completion (Estimated)

November 30, 2026

Last Updated

June 15, 2026

Record last verified: 2026-06

Locations