NCT07628478

Brief Summary

This study aims to compare the effects of low-intensity blood flow restriction training combined with resistance training versus traditional high-intensity resistance training on body composition (skeletal muscle mass, body fat mass) and maximal strength (isometric mid-thigh pull, vertical jump, isometric squat pull) in male military academy cadets. The study lasts for 6 weeks and adopts a randomized parallel-group design.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
36

participants targeted

Target at P25-P50 for not_applicable

Timeline
2mo left

Started Jun 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress25%
Jun 2026Jul 2026

First Submitted

Initial submission to the registry

May 29, 2026

Completed
3 days until next milestone

Study Start

First participant enrolled

June 1, 2026

Completed
4 days until next milestone

First Posted

Study publicly available on registry

June 5, 2026

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 20, 2026

Expected
8 days until next milestone

Study Completion

Last participant's last visit for all outcomes

July 28, 2026

Last Updated

June 5, 2026

Status Verified

June 1, 2026

Enrollment Period

2 months

First QC Date

May 29, 2026

Last Update Submit

June 4, 2026

Conditions

Physical FitnessMuscle StrengthBody Composition

Outcome Measures

Primary Outcomes (1)

  • Peak Force in Isometric Mid-Thigh Pull (IMTP)

    Maximal vertical ground reaction force during isometric mid-thigh pull measured on ELIGA portable force plate. Participants pull a fixed bar with knee angle 125°-135° for 3-5 seconds. Best of 2 trials recorded in Newtons (N).

    Baseline (T1), Week 3 (T2), Week 6 (T3)

Secondary Outcomes (2)

  • Countermovement Jump Height (CMJ)

    Baseline (T1), Week 6 (T3)

  • Body Fat Mass

    Baseline (T1), Week 6 (T3)

Study Arms (2)

Low-Load Blood Flow Restistance Training (LL-BFR)

EXPERIMENTAL

Participants perform low-load resistance training (30% 1RM) combined with blood flow restriction. Lower extremity exercises include squat, deadlift, weighted lunge, and resisted running. Pneumatic cuffs (KAATSU Master) are applied at the proximal thigh at 200 mmHg during exercise and rest intervals. Training: 1 set of 30 reps, followed by 3 sets of 15 reps; 60-second rest between sets; 3 days/week for 6 weeks.

Device: KAATSU Master Pneumatic Cuff

Traditional High-Load Resistance Training (HL-RT)

ACTIVE COMPARATOR

Participants perform traditional high-load resistance training at 70% 1RM. Same exercises as experimental group: squat, deadlift, weighted lunge, and resisted running. 4 sets of 8-12 reps; 3-minute rest between sets; 3 days/week for 6 weeks.

Behavioral: High-Load Resistance Training

Interventions

KAATSU Master Pneumatic CuffDEVICE

Pneumatic pressure cuffs applied to the proximal thigh at 200 mmHg to achieve partial blood flow restriction during low-load resistance training (30% 1RM). Initial warm-up at 40 mmHg.

Low-Load Blood Flow Restistance Training (LL-BFR)
High-Load Resistance TrainingBEHAVIORAL

Traditional resistance training at 70% of one-repetition maximum (1RM) without blood flow restriction.

Traditional High-Load Resistance Training (HL-RT)

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Male cadets from military academy;
  • No contraindications to blood flow restriction training (no circulatory diseases, skin allergies);
  • Healthy and capable of high-intensity exercise;
  • Signed informed consent

You may not qualify if:

  • Major sports injury within 2 years (fracture, ligament tear, muscle/tendon rupture, habitual joint dislocation);
  • Cardiovascular or visceral organ diseases;
  • Other conditions unsuitable for training

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Physical Training Hall

Changsha, Changsha, 410073, China

RECRUITING

Related Publications (1)

  • Yang K, Chee CS, Abdul Kahar J, Tengku Kamalden TF, Li R, Qian S. Effects of blood flow restriction training on physical fitness among athletes: a systematic review and meta-analysis. Sci Rep. 2024 Jul 18;14(1):16615. doi: 10.1038/s41598-024-67181-9.

    PMID: 39025894BACKGROUND

Related Links

Central Study Contacts

Pangfeng Liu Liu

CONTACT

18569427353965004077@qq.com

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Doctoral degree

Study Record Dates

First Submitted

May 29, 2026

First Posted

June 5, 2026

Study Start

June 1, 2026

Primary Completion (Estimated)

July 20, 2026

Study Completion (Estimated)

July 28, 2026

Last Updated

June 5, 2026

Record last verified: 2026-06

Data Sharing

IPD Sharing
Will share

Locations

CN(1)