Ultrasound-Guided Transversalis Fascia Plane Block Versus Quadratus Lumborum Plane Block for Analgesia After Appendectomy in Pediatrics

NCT07618650 | Enrolling By Invitation

• 1 other identifier: 36264MS975/6/25
• Study Type: interventional
• Target: 70
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to compare the effectiveness of ultrasound-guided Transversalis Fascia Plane block versus Quadratus Lumborum block for postoperative pain relief in pediatrics undergoing appendectomy. Primary outcomes:

• Proportion of patients needing rescue analgesia within the first 24 postoperative hours. Secondary outcomes:
• Visual Analogue Scale pain intensity measurements.
• Intraoperative Heart rate and mean arterial blood pressure will be recorded.
• Time to first analgesic request for patients needing rescue analgesia (Fentanyl).
• Block-related complications (e.g., hematoma, local anesthetic toxicity, lower limb weakness).
• Parents' satisfaction score.

Conditions

Transversalis Fascia Plane Block; Quadratus Lumborum Block; Appendectomy

Keywords

Transversalis Fascia Plane Block; Quadratus Lumborum Plane Block; Appendectomy; Pediatrics

Outcome Measures

Primary Outcomes (1)

• Proportion of patients needing rescue analgesia

  within the first 24 postoperative hours.

Secondary Outcomes (1)

• Visual Analogue Scale

  24 postoperative hours

Study Arms (2)

Group I: Transversalis Fascia Plane Block versus

EXPERIMENTAL

Patients will receive general anesthesia and ultrasound-guided transversalis fascia plane block in a dose of 0.4 ml/kg of 0.25% bupivacaine administered prior to surgical excision

Procedure: Transversalis Fascia Plane Block group

Group II :Quadratus Lumborum Plane Block

EXPERIMENTAL

patients will receive general anesthesia and a quadratus lumborum plane block in a dose of 0.4 ml/kg of 0.25% bupivacaine administered prior to surgical excision.

Procedure: Quadratus Lumborum Plane Block group

Interventions

Transversalis Fascia Plane Block group PROCEDURE

35 Patients will receive general anesthesia and ultrasound-guided transversalis fascia plane block in a dose of 0.4 ml/kg of 0.25% bupivacaine administered prior to surgical excision.

Group I: Transversalis Fascia Plane Block versus

Quadratus Lumborum Plane Block group PROCEDURE

35 patients will receive general anesthesia and a quadratus lumborum plane block in a dose of 0.4 ml/kg of 0.25% bupivacaine administered prior to surgical excision

Group II :Quadratus Lumborum Plane Block

Eligibility Criteria

• Age: 7 Years - 12 Years
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• patients aged between 7 and 12 years of both sexes undergoing appendectomy, American Society of Anesthesiologists (ASA) physical status of I or II

You may not qualify if:

• Refusal of parents to participate
• Patients with peritonitis
• History of allergy to bupivacaine and other amide local anesthetics
• Infection at the site of block needle entry
• Bleeding diathesis
• Neurological disorders
• American Society of Anesthesiologists ≥ III

Sponsors & Collaborators

• Tanta University: lead

Study Sites (1)

Tanta University

Tanta, Egypt

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident

Study Record Dates

• First Submitted: May 25, 2026
• First Posted: June 1, 2026
• Study Start: June 30, 2025
• Primary Completion: May 20, 2026
• Study Completion: May 20, 2026
• Last Updated: June 1, 2026

Record last verified: 2025-06

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP, ICF

Locations

EG (1)