NCT07605871

Brief Summary

The objective of this study is to evaluate the effect of oral collagen drink and MAXI collagen drink on human skin condition improvement.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
105

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started May 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 8, 2026

Completed
4 days until next milestone

Study Start

First participant enrolled

May 12, 2026

Completed
14 days until next milestone

First Posted

Study publicly available on registry

May 26, 2026

Completed
20 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 15, 2026

Completed
15 days until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2026

Completed
Last Updated

July 10, 2026

Status Verified

July 1, 2026

Enrollment Period

1 month

First QC Date

May 8, 2026

Last Update Submit

July 8, 2026

Conditions

Skin ConditionCollagen Synthesis

Keywords

MAXI CollagenHydrolyzed collagenOral Collagen

Outcome Measures

Primary Outcomes (1)

  • The change of collagen fiber fluorescence intensity

    SUPERVISION-780 In-Vivo Imaging System (Survface, China) was utilized to evaluate the density and quality of dermal collagen fibers.

    Change from Baseline collagen intensity at 4 weeks

Secondary Outcomes (17)

  • The change of skin elasticity

    Change from Baseline skin elasticity at 4 weeks

  • The change of skin firmness

    Change from Baseline skin firmness at 4 weeks

  • The change of epidermal thickness

    Change from Baseline epidermal thickness at 4 weeks

  • The change of cheek skin roughness

    Change from Baseline skin roughness at 4 weeks

  • The change of the Dermal-Epidermal Junction (DEJ) structures

    Change from Baseline DEJ status at 4 weeks

  • +12 more secondary outcomes

Other Outcomes (4)

  • The change of skin brightness (L*)

    Change from Baseline skin brightness (L*) at 4 weeks

  • The change of skin individual typology angle (ITA)

    Change from Baseline skin ITA at 4 weeks

  • The change of skin color parameters

    Change from Baseline skin redness (a*) at 4 weeks

  • +1 more other outcomes

Study Arms (3)

Collagen Drink

ACTIVE COMPARATOR

oral intake 5 g collagen daily

Dietary Supplement: Collagen Drink

MAXI Collagen Drink

EXPERIMENTAL

oral intake 15 mL MAXI collagen daily (equivalent to 5 g of deep hydrolyzed collagen net weight)

Dietary Supplement: MAXI Collagen Drink

MAXI Collagen Drink_High dose

EXPERIMENTAL

oral intake 30 mL MAXI collagen daily (equivalent to 10 g of deep hydrolyzed collagen net weight)

Dietary Supplement: MAXI Collagen Drink_High dose

Interventions

Collagen DrinkDIETARY_SUPPLEMENT

consume 1 bottle of the test samples daily for 4 consecutive weeks, each bottle containing 5 g Collagen Powder

Collagen Drink
MAXI Collagen DrinkDIETARY_SUPPLEMENT

consume 1 bottle of the test samples daily for 4 consecutive weeks, each bottle containing 15 mL MAXI Collagen Liquid (equivalent to 5 g of deep hydrolyzed collagen net weight)

MAXI Collagen Drink
MAXI Collagen Drink_High doseDIETARY_SUPPLEMENT

consume 1 bottle of the test samples daily for 4 consecutive weeks, each bottle containing 30 mL MAXI Collagen Liquid (equivalent to 10 g of deep hydrolyzed collagen net weight)

MAXI Collagen Drink_High dose

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Healthy Chinese subjects aged 18 to 60 years, both male and female.
  • Wrinkle Severity: Crow's feet graded 2-4; under-eye fine lines graded 2-5; nasolabial folds graded 1-3.
  • Presence of facial skin laxity and sagging.
  • Ability to undergo skin examinations and pre-treatment in the designated test areas.
  • Ability to understand the trial process, participate voluntarily, and sign a written Informed Consent Form (ICF).

You may not qualify if:

  • Pregnant or lactating women, or those planning to become pregnant in the near future.
  • Highly sensitive constitution, history of allergic diseases, or history of allergies to cosmetics.
  • Presence of skin diseases (e.g., psoriasis, eczema, atopic dermatitis, severe acne) or other chronic systemic diseases.
  • Skin conditions in the test area such as birthmarks, hyperpigmentation, inflammation, scars, nevi (moles), or hypertrichosis (excessive hair).
  • Use of anti-inflammatory drugs (e.g., oral or topical corticosteroids) within the past month.
  • Use of cosmetics or other products with similar efficacy within the past 2 weeks.
  • Participation in other human clinical trials for cosmetics within the past month.
  • Any other conditions deemed unsuitable for participation based on clinical assessment.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Beijing Ewish Testing Technology Co.,ltd.

Beijing, China

Location

MeSH Terms

Conditions

Skin Diseases

Condition Hierarchy (Ancestors)

Skin and Connective Tissue Diseases

Study Officials

  • YAO PAN

    Beijing Ewish Testing Technology Co.,ltd.

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 8, 2026

First Posted

May 26, 2026

Study Start

May 12, 2026

Primary Completion

June 15, 2026

Study Completion

June 30, 2026

Last Updated

July 10, 2026

Record last verified: 2026-07

Locations

CN(1)