Evaluation of an Instructional Video About Medication Management During Admission and Medication Adherence for Kidney Transplantation and in the Outpatient Clinic in a Dutch University Hospital.

NCT07592624 | Not Yet Recruiting

• 1 other identifier: 14372
• Study Type: interventional
• Target: 308
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this RCT is to evaluate the effect of the instructional video on improving patient compliance and reducing medication errors. The study will include adult kidney transplant recipients (18 years or older) at Erasmus MC who have undergone a kidney transplantation starting January 2026. The main questions it aims to answer: The primary aim of this study is to assess whether our developed video instruction, compared with the traditional verbal instruction, both of which are given shortly before training during admission, reduces the number of medication errors in kidney transplant patients. The study will also examine the correlation between patient characteristics (such as age, comorbidities, and language proficiency) and medication errors. Additionally, patient-reported medication errors will be measured through a questionnaire completed during follow-up visits at the outpatient clinic, which is part of standard care. The instructional video will be evaluated by a short questionnaire.

Conditions

Kidney Transplant; Adult; Instruction Videos; Medication Adherence

Outcome Measures

Primary Outcomes (1)

• Incidence and type of medication errors during admission

  The primary outcome of this study will be the incidence (number of medication errors) and type of medication errors ( 1)Medication preparation omitted, 2) Incorrect dosage, 3) Incorrect administration at the scheduled time, 4), Medication discontinued inappropriately, 5)Error not documented by the nurse) during admission, evaluated through direct observation by healthcare providers. These errors will be documented and reported via patient portals by nurses.

  During admission

Secondary Outcomes (3)

• Patient characteristics

  During admission

• Evaluation of the instructional video

  At the end of admission

• BAASIS

  During the first year follow up at the out patient clinic after kidney transplantation in the Erasmus MC

Study Arms (2)

Verbal instruction

NO INTERVENTION

Patients receive the verbal instruction about medication training from the nurses.

Video instruction

EXPERIMENTAL

Patients receive the instruction video about medication training from the nurses.

Other: Instructional video about medication administration

Interventions

Instructional video about medication administration OTHER

Self developed instructional video for a Dutch university hospital, for Dutch kidney transplant patients. Instructional video is about medication administration during admission.

Video instruction

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• The patient is able to take the medication independently or with the help of someone else (professionals not included).
• After admission, the patient is discharged to their own home or home of friend/relative.
• The patient had a follow up at the outpatient clinic in the Erasmus Medical Center for at least one year after transplantation.
• The patient is able to read the medication list or an illiteracy-friendly medication list.

You may not qualify if:

• Patients under 18 years of age
• Patients who got discharged with a medication dispenser
• Refusal to participate in the study.
• Cognitive impairments that hinder participation.
• Patients and/or family who can not understand (language barrier) the instructional video.

Sponsors & Collaborators

• Erasmus Medical Center: lead

Study Sites (1)

Erasmus Medical Center

Rotterdam, 3015GD, Netherlands

Location

MeSH Terms

Conditions

Medication Adherence

Condition Hierarchy (Ancestors)

Patient Compliance; Patient Acceptance of Health Care; Treatment Adherence and Compliance; Health Behavior; Behavior

Study Officials

• Jacqueline van de Wetering, MD, Dr.

  Erasmus Medical Center

  STUDY CHAIR

Central Study Contacts

Myrthe van der Zanden, MSc, Drs

CONTACT

+31650094899; m.vanderzanden@erasmusmc.nl

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: March 12, 2026
• First Posted: May 18, 2026
• Study Start (Estimated): July 1, 2026
• Primary Completion (Estimated): May 31, 2027
• Study Completion (Estimated): December 31, 2027
• Last Updated: May 18, 2026

Record last verified: 2026-05

Locations

NL (1)