NCT07588893

Brief Summary

This study aims to evaluate the acute effects of Buerger-Allen exercises on lower extremity circulation in sedentary office workers. Prolonged sitting is associated with reduced venous return, impaired peripheral circulation, and endothelial dysfunction. Buerger-Allen exercises are simple position-based exercises designed to enhance arterial blood flow, venous return, and tissue perfusion. Thirty-five healthy sedentary adults aged 18 to 45 years will participate in this single-group pretest-posttest clinical trial. Skin surface temperature, capillary refill time, ankle-brachial index, peripheral oxygen saturation, and heart rate will be measured before and after a single 20-minute exercise session. The findings may support the use of Buerger-Allen exercises as a practical, low-cost physiotherapy strategy to improve peripheral circulation and reduce the adverse vascular effects of prolonged sitting.

Trial Health

63
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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
35

participants targeted

Target at P25-P50 for not_applicable

Timeline
6mo left

Started Jun 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 9, 2026

Completed
6 days until next milestone

First Posted

Study publicly available on registry

May 15, 2026

Completed
17 days until next milestone

Study Start

First participant enrolled

June 1, 2026

Expected
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2026

3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2026

Last Updated

May 15, 2026

Status Verified

May 1, 2026

Enrollment Period

3 months

First QC Date

May 9, 2026

Last Update Submit

May 9, 2026

Conditions

Keywords

Buerger-Allen ExercisePeripheral CirculationSedentary BehaviorOffice WorkersCapillary Refill TimeAnkle-Brachial IndexInfrared ThermographyPhysiotherapy

Outcome Measures

Primary Outcomes (2)

  • Skin Surface Temperature

    Skin surface temperature measured with an infrared thermometer in degrees Celsius (°C). Higher values indicate increased peripheral blood flow and tissue perfusion.

    Baseline, Immediately After Intervention, and 10 Minutes After Intervention

  • Capillary Refill Time

    Capillary refill time measured in seconds. Shorter times indicate improved peripheral microcirculation and tissue perfusion.

    Baseline, Immediately After Intervention, and 10 Minutes After Intervention

Secondary Outcomes (3)

  • Ankle-Brachial Index (ABI)

    Baseline, Immediately After Intervention, and 10 Minutes After Intervention

  • Peripheral Oxygen Saturation (SpO₂)

    Baseline, Immediately After Intervention, and 10 Minutes After Intervention

  • Heart Rate

    Baseline, Immediately After Intervention, and 10 Minutes After Intervention

Study Arms (1)

Buerger-Allen Exercise Group

EXPERIMENTAL

Participants will perform a single standardized 20-minute Buerger-Allen exercise session. Lower extremity circulatory parameters will be assessed before the intervention, immediately after the intervention, and 10 minutes after the intervention.

Behavioral: Buerger-Allen Exercise Program

Interventions

The intervention consists of a standardized Buerger-Allen exercise protocol involving three sequential positions: (1) elevation of the lower limbs above heart level to facilitate venous return, (2) dependency of the lower limbs to promote arterial blood flow, and (3) horizontal supine rest to stabilize circulation. The complete exercise session lasts approximately 20 minutes and is performed once. Lower extremity circulatory parameters are assessed at baseline, immediately after the intervention, and 10 minutes after the intervention.

Buerger-Allen Exercise Group

Eligibility Criteria

Age18 Years - 45 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Healthy sedentary office workers
  • Age between 18 and 45 years
  • Sitting for at least 6 hours per day for work-related activities
  • Not meeting regular physical activity recommendations
  • Willing to participate voluntarily and provide written informed consent

You may not qualify if:

  • History of peripheral arterial disease, deep vein thrombosis, or other vascular disorders
  • Cardiovascular, neurological, or musculoskeletal conditions that may affect lower extremity circulation or prevent exercise participation
  • Diabetes mellitus
  • Current smoking
  • Pregnancy
  • Use of medications that may significantly affect peripheral circulation
  • Lower extremity injury or surgery within the previous 6 months
  • Participation in regular structured exercise programs

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

İstanbul Gelisim University

Istanbul, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Sedentary Behavior

Condition Hierarchy (Ancestors)

Behavior

Study Officials

  • Busenur KARAGÖZ, MSc

    İstanbul Gelisim University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Busenur KARAGÖZ, MSc

CONTACT

Gökay ÇAKIROĞLU, PT

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
PREVENTION
Intervention Model
SINGLE GROUP
Model Details: All participants will undergo a single standardized Buerger-Allen exercise session. Lower extremity circulatory parameters will be assessed before the intervention, immediately after the intervention, and 10 minutes after the intervention.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Lecturer

Study Record Dates

First Submitted

May 9, 2026

First Posted

May 15, 2026

Study Start (Estimated)

June 1, 2026

Primary Completion (Estimated)

September 1, 2026

Study Completion (Estimated)

December 1, 2026

Last Updated

May 15, 2026

Record last verified: 2026-05

Data Sharing

IPD Sharing
Will not share

Individual participant data will not be made publicly available because no formal data-sharing plan has been established for this investigator-initiated academic study.

Locations