NCT06754579

Brief Summary

Engaging in regular and appropriately structured physical activities is a critical component of an individual's lifestyle and represents a lifelong habit essential for promoting overall well-being. Research increasingly emphasizes the significance of such activities, particularly in the prevention and management of various health conditions (Martin, Richardson, Weiller, \& Jackson, 2004).A sedentary lifestyle is considered one of the most serious health issues faced by individuals in the modern world.Previous research has established high-intensity interval training (HIIT) as an effective method for enhancing cardiovascular health, sparking interest in the relationship between exercise intensity and cognitive function. Most studies to date have focused on treadmill and lower extremity ergometer exercises; however, evidence regarding the efficacy of high-volume upper extremity exercises in improving physical and cognitive performance among sedentary adults remains limited and inconsistent. Upper extremity motor function has been proposed as a potential biomarker for cognitive impairment and may contribute to distinguishing healthy aging trajectories. This study aims to compare the effects of high-volume and low-volume upper extremity exercise in sedentary adults, testing the hypothesis that one exercise regimen may be superior in enhancing both physical and cognitive performance, as well as cognitive function.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
32

participants targeted

Target at P25-P50 for not_applicable

Timeline
8mo left

Started Jan 2025

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress68%
Jan 2025Dec 2026

First Submitted

Initial submission to the registry

December 23, 2024

Completed
9 days until next milestone

First Posted

Study publicly available on registry

January 1, 2025

Completed
Same day until next milestone

Study Start

First participant enrolled

January 1, 2025

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2026

Expected
29 days until next milestone

Study Completion

Last participant's last visit for all outcomes

December 30, 2026

Last Updated

January 21, 2026

Status Verified

January 1, 2026

Enrollment Period

1.9 years

First QC Date

December 23, 2024

Last Update Submit

January 16, 2026

Conditions

Keywords

upper limbreaction timepyhsical performancecognitive performance

Outcome Measures

Primary Outcomes (1)

  • International Physical Activity Questionnaire-Short Form (IFQQ-SF)

    International Physical Activity Questionnaire-Short Form (IFQQ-SF): UFQ-SF was developed by Craig and colleagues to determine the physical activity levels of individuals between the ages of 15-65. The short form is recommended more because the long form is boring and repetitive, so the "last 7 days" short form was used in our study. The short form (7 questions) provides information on time spent in sitting, walking, moderate-intensity and vigorous activities. The total score is expressed as one MET-min/week and is obtained by multiplying the number of days and minutes of walking, moderate-intensity and vigorous activity and the MET score.

    eight weeks

Secondary Outcomes (6)

  • Maximal Arm Exercise Capacity

    Eight weeks

  • Stroop Test

    Eight weeks

  • Reaction Time

    Eight weeks

  • Hole Type Steadiness Tester

    Eight weeks

  • Postural Sway Assessment

    Eight weeks

  • +1 more secondary outcomes

Study Arms (2)

High-Volume Upper Extremity Exercises Training

EXPERIMENTAL

The High volume upper extremity protocol consists of a 5-min warm-up at 60%-70% of max HR using an arm ergometer, followed by four 4-min work sessions reaching 90%-95% of max W, followed by a 3-min active recovery period at 60% max W. The exercise session is terminated by a 5-min cool-down at 60%-70% max W. The total exercise duration will be 35 minutes.

Other: High-Volume Upper Extremity Exercises Training

Low Volume Upper Extremity Exercises Training

EXPERIMENTAL

Low volume upper extremity exercise training will be applied using an arm ergometer consisting of a 5-minute warm-up at 40% of max W, followed by 25 minutes of active training at 60-70% of max W and a 5-minute cool-down at 40% of max.

Other: Low Volume Upper Extremity Exercises Training

Interventions

The group will be trained 3 days a week for a total of 8 weeks.

High-Volume Upper Extremity Exercises Training

The group will be trained 3 days a week for a total of 8 weeks.

Low Volume Upper Extremity Exercises Training

Eligibility Criteria

Age18 Years - 50 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Individuals aged between 18-50 years.
  • Defined as engaging in less than 150 minutes of moderate-intensity physical activity per week

You may not qualify if:

  • diagnosis of neurological, cardiovascular, musculoskeletal, or other systemic diseases that may affect physical activity or exercise capacity.
  • diagnosed cognitive impairments or psychiatric disorders that could interfere with test participation.
  • acute injuries or surgeries within the past six months that could restrict movement or participation.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Fatma Kübra Çekok

Tarsus, Mersi̇n, 33400, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Sedentary Behavior

Condition Hierarchy (Ancestors)

Behavior

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Masking Details
Study participants are unaware of their assigned group
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: The study was planned as a randomized controlled study
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Asst.prof

Study Record Dates

First Submitted

December 23, 2024

First Posted

January 1, 2025

Study Start

January 1, 2025

Primary Completion (Estimated)

December 1, 2026

Study Completion (Estimated)

December 30, 2026

Last Updated

January 21, 2026

Record last verified: 2026-01

Locations