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Effect of Thoracic Manipulation on Peripheral Muscle Oxygenation, Pain, and Disability in Office Workers With Back Pain
Sponsor study identifier
interventional
48
1 country
1
Study Start
March 10, 2025
Actual (reported)Primary Completion
May 15, 2025
Actual (reported)Study Completion
May 30, 2025
Actual (reported)Office workers spend 70-85% of their time sitting, which leads to postural disorders and musculoskeletal system diseases. Back pain is the most common health problem among office workers who need to sit. Studies have shown that spinal manipulation can help reduce back pain by decreasing the stiffness of spine segments associated with joint dysfunction. The primary aim of this study is to investigate the effects of thoracic spinal manipulation on peripheral oxygenation, pain, and disability of the back muscles in office workers with back pain, at acute, 10-day, and 4-week follow-up periods. The secondary aim is to evaluate whether the parameters have a significant relationship. The study will include volunteers aged 20-50 who are active office workers with no orthopedic, neurological, or psychological disorders, who have experienced back pain in the last 3 months, and who have a numerical pain scale score of at least 30 mm out of 100 mm. Participants will be randomized into the thoracic spinal manipulation and the control groups. Both groups will receive postural exercises. The thoracic spinal manipulation group will receive a single session of spinal manipulation, while the control group will only receive postural exercises. The study is expected to find significant improvement in peripheral muscle oxygenation, back pain, and disability scores following thoracic spinal manipulation. This study aims to contribute to the literature by focusing on how peripheral muscle oxygenation is affected by thoracic spinal manipulation.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
May 30, 2025
Actual (reported)Click on a node to explore related trials.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
October 2, 2024
Actual (reported)November 26, 2024
Actual (reported)March 10, 2025
Actual (reported)May 15, 2025
Actual (reported)May 30, 2025
Actual (reported)Periferal muscle oxygen measurement
Muscle oxygen levels will be measured using the Moxy Monitor. The Moxy Monitor is a mobile, non-invasive method for measuring SmO2. The device uses near-infrared spectroscopy (NIRS) technology and features a patented algorithm that measures hemoglobin and myoglobin in capillaries and muscle tissues with a wearable monitor. Moxy device measures real-time muscle oxygenation (SmO2) and total hemoglobin (tHb) levels by using near-infrared spectroscopy.
Baseline, right after intervention, ten days after post intervention, four weeks after post intervention
Oswestry Disability Index
Baseline, right after intervention, ten days after post intervention, four weeks after post intervention
Thoracic spinal manipulation will be performed between the T1-T12 vertebral levels, based on the segment with movement limitations. The manipulation will be applied to the area of back pain using a high-velocity, low-amplitude thrust with a short-lever technique. Also, the same postural exercises that were given to the control group will be given.
The postural exercises program will be given.
Thoracal manipulation will be applied only one session.
Both groups will perform the same postural exercises, which will be applied twice a week for 4 weeks. The intervention group will receive thoracic manipulation for one session.
Bahcesehir University
Beşiktaş, Istanbul, 34353, Turkey (Türkiye)
Alev Atasever, PT
Bahcesehir University, Graduate Education Institute,Chiropractic Master of Science Program
Pelin Pişirici, PT, PhD
Bahcesehir University, Faculty of Health Sciences
Berkay Eren Pejlivanoğlu, PT, PhD
Bahcesehir University, Health Sciences Faculty, Physiotherapy and Rehabilitation
48 participants (actual enrollment reported by the registry).
First Submitted
October 2, 2024
First Posted
November 26, 2024
Study Start
March 10, 2025
Actual (reported)Neck Disability Index
Baseline, right after intervention, ten days after post intervention, four weeks after post intervention
Numeric Pain Scale
Baseline, right after intervention, ten days after post intervention, four weeks after post intervention
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Contact the study team to confirm eligibility.
Primary Completion
May 15, 2025
Actual (reported)Study Completion
May 30, 2025
Actual (reported)Last Updated
July 8, 2025
Record last verified: 2025-07
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Source: ClinicalTrials.gov.
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