Taiwan ED Airway Quality Surveillance Registry (TEAR)

NCT07574450 | Not Yet Recruiting

• 1 other identifier: 202501836B0
• Study Type: observational
• Target: 1,200
• Locations: 1 country
• Sites: 1

Brief Summary

This prospective, multicenter observational registry systematically captures all emergency department tracheal intubations across participating hospitals in Taiwan. The registry focuses on process quality indicators, including first-pass success, and patient-safety outcomes, including hypoxemia, hypotension, and peri-intubation cardiac arrest within 30 minutes of intubation. Routinely generated laboratory and physiologic variables are also collected to improve risk stratification and identify predictors of major adverse events. The study is non-interventional and does not alter clinical care.

Conditions

Airway Management; Tracheal Intubation; Emergency Department; Peri-intubation Adverse Events

Keywords

first-pass success; hypoxemia; hypotension; cardiac arrest; registry

Outcome Measures

Primary Outcomes (1)

• Incidence of major adverse peri-intubation events within 30 minutes after the start of intubation

  severe hypoxemia, severe hypotension/cardiovascular instability, or cardiac arrest.

  Periprocedural, through 30 minutes after the start of intubation

Secondary Outcomes (2)

• First-pass success

  Periprocedural

• In-hospital mortality

  From intubation to hospital discharge, assessed up to 90 days

Other Outcomes (1)

• Pre-intubation severe metabolic acidosis

  Within 2 hours before the start of intubation

Study Arms (1)

Adult patients in ED require emergent tracheal intubation

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Consecutive adult emergency department patients undergoing tracheal intubation at participating hospitals in Taiwan.

You may qualify if:

• Undergoing tracheal intubation in the emergency department during the study period

You may not qualify if:

• Prehospital intubation; intubation performed solely for elective anesthesia/procedural sedation outside emergency indications

Sponsors & Collaborators

• Chang Gung Memorial Hospital: lead

Study Sites (1)

New Taipei Municipal Tucheng Hospital, New Taipei City, Taiwan

New Taipei City, Taiwan

Location

Related Publications (7)

• Garcia SI, Smischney NJ, Sandefur BJ, D'Andria Ursoleo J, Kelm DJ, Wieruszewski PM. Peri-intubation Cardiovascular Collapse During Emergency Airway Management. Pulm Ther. 2025 Dec;11(4):569-585. doi: 10.1007/s41030-025-00326-x. Epub 2025 Oct 16.

  PMID: 41094343 BACKGROUND

• Hasegawa K, Hagiwara Y, Chiba T, Watase H, Walls RM, Brown DF, Brown CA 3rd; Japanese Emergency Medicine Research Alliance. Emergency airway management in Japan: Interim analysis of a multi-center prospective observational study. Resuscitation. 2012 Apr;83(4):428-33. doi: 10.1016/j.resuscitation.2011.11.027. Epub 2011 Dec 8.

  PMID: 22155701 BACKGROUND

• Maia IWA, Besen BAMP, Silva LOJE, von Hellmann R, Hajjar LA, Sandefur BJ, Pedrollo DF, Nogueira CG, Figueiredo NMP, Miranda CH, Martins D, Baumgratz TD, Bergesch B, Costa D, Colleoni O, Zanettini J, Freitas AP, Moreira NP, Gaspar PL, Tambelli R, Costa MC, Silveira S, Correia W, de Maria RG, Filho UAV, Weber AP, da Silva Castro V, Dornelles CFD, Tabach BS, Guimaraes HP, Stanzani G, Gava TF, Mullan A, Souza HP, Ranzani OT, Bellolio F, Alencar JCG; BARCO group. Peri-intubation adverse events and clinical outcomes in emergency department patients: the BARCO study. Crit Care. 2025 Apr 17;29(1):155. doi: 10.1186/s13054-025-05392-w.

  PMID: 40247381 BACKGROUND

• Cho J, Cho YS, You JS, Lee HS, Kim H, Chung HS; Korean Emergency Airway Management Society. Current status of emergency airway management for elderly patients in Korea: Multicentre study using the Korean Emergency Airway Management Registry. Emerg Med Australas. 2013 Oct;25(5):439-44. doi: 10.1111/1742-6723.12122. Epub 2013 Sep 9.

  PMID: 24099373 BACKGROUND

• April MD, Arana A, Reynolds JC, Carlson JN, Davis WT, Schauer SG, Oliver JJ, Summers SM, Long B, Walls RM, Brown CA 3rd; NEAR Investigators. Peri-intubation cardiac arrest in the Emergency Department: A National Emergency Airway Registry (NEAR) study. Resuscitation. 2021 May;162:403-411. doi: 10.1016/j.resuscitation.2021.02.039. Epub 2021 Mar 5.

  PMID: 33684505 BACKGROUND

• Alkhouri H, Vassiliadis J, Murray M, Mackenzie J, Tzannes A, McCarthy S, Fogg T. Emergency airway management in Australian and New Zealand emergency departments: A multicentre descriptive study of 3710 emergency intubations. Emerg Med Australas. 2017 Oct;29(5):499-508. doi: 10.1111/1742-6723.12815. Epub 2017 Jun 5.

  PMID: 28582801 BACKGROUND

• Russotto V, Myatra SN, Laffey JG, Tassistro E, Antolini L, Bauer P, Lascarrou JB, Szuldrzynski K, Camporota L, Pelosi P, Sorbello M, Higgs A, Greif R, Putensen C, Agvald-Ohman C, Chalkias A, Bokums K, Brewster D, Rossi E, Fumagalli R, Pesenti A, Foti G, Bellani G; INTUBE Study Investigators. Intubation Practices and Adverse Peri-intubation Events in Critically Ill Patients From 29 Countries. JAMA. 2021 Mar 23;325(12):1164-1172. doi: 10.1001/jama.2021.1727.

  PMID: 33755076 BACKGROUND

MeSH Terms

Conditions

Emergencies; Hypoxia; Hypotension; Heart Arrest

Condition Hierarchy (Ancestors)

Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Signs and Symptoms, Respiratory; Signs and Symptoms; Vascular Diseases; Cardiovascular Diseases; Heart Diseases

Central Study Contacts

TING HAO YANG, Doctor

CONTACT

+886978989007; mr2434@cgmh.org.tw

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Month
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Doctor

Study Record Dates

• First Submitted: April 27, 2026
• First Posted: May 8, 2026
• Study Start (Estimated): August 1, 2026
• Primary Completion (Estimated): July 1, 2029
• Study Completion (Estimated): December 1, 2029
• Last Updated: May 8, 2026

Record last verified: 2026-05

Data Sharing

• IPD Sharing: Will not share

Locations

TW (1)