NCT07568925

Brief Summary

The musculoskeletal system represents a holistic movement organization emerging from the integrated function of the central nervous system, musculoskeletal structures, and joint complexes. This organization is defined in the literature as the kinetic chain, characterized by the sequential and coordinated activation of body segments to enable distal segments to perform activities with optimal speed, position, and timing. The efficiency of the kinetic chain depends on optimal length-tension relationships, neuromuscular control, and balanced load transfer between segments. As the initial point of contact with the ground, the foot functions not merely as a passive support surface but as a dynamic structure actively involved in postural control, balance, and the regulation of ground reaction forces. Plantar pressure distribution and Center of Pressure (CoP) dynamics are considered objective indicators of foot-ground interaction. Due to its complex anatomical and biomechanical structure, any mechanical disturbance within the foot can influence the loading patterns of the entire kinetic chain.Abnormal plantar pressure distribution-characterized by increased peak pressures, altered forefoot-rearfoot load ratios, and increased CoP variability-may lead to compensatory load redistribution in proximal joints. These compensations have been associated with altered motor strategies, reduced neuromuscular control, and impaired shock absorption. Consequently, such alterations may contribute to the development of pain in proximal regions. This suggests a potential association between plantar pressure patterns and pain localization and severity in young adults.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
53

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started May 2026

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 23, 2026

Completed
8 days until next milestone

Study Start

First participant enrolled

May 1, 2026

Completed
Same day until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2026

Completed
5 days until next milestone

First Posted

Study publicly available on registry

May 6, 2026

Completed
Last Updated

May 6, 2026

Status Verified

May 1, 2026

Enrollment Period

Same day

First QC Date

April 23, 2026

Last Update Submit

May 1, 2026

Conditions

Outcome Measures

Primary Outcomes (2)

  • Plantar Pressure Measurement

    Plantar pressure measurements will be performed using a pedobarography system (GHF550 Foot Checker). The device includes a 480 × 480 mm sensor platform with 2304 sensors and a sampling frequency of up to 60 Hz. Assessment of static and dynamic plantar pressure parameters using a pedobarography system, including pressure distribution, load characteristics, contact area, and related biomechanical variables.

    Baseline

  • Pain İntensity

    Pain intensity will be assessed using the Visual Analog Scale (VAS). Participants will be asked to rate their current pain level on a 10-cm horizontal line, where 0 indicates "no pain" and 10 indicates "worst imaginable pain." Pain localization will also be recorded based on participant self-report.

    Baseline

Study Arms (1)

Single Group

Other: Plantar Pressure Measurement

Interventions

Plantar pressure measurements will be performed using a pedobarography system. Both static and dynamic assessments will be conducted using the device.In addition, age, height, and body weight will be recorded, and body mass index (BMI) will be calculated based on these measurements. Participants' commonly used footwear type, pain localization, and pain intensity will also be assessed.

Single Group

Eligibility Criteria

Age18 Years - 35 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Participants will be recruited using a convenience sampling method from the local population, primarily consisting of university students and their peers.

You may qualify if:

  • Young adults aged between 18 and 35 years
  • Ability to stand and walk independently
  • Adequate cognitive function to understand and follow the measurement procedures
  • Willingness to participate voluntarily and provide written informed consent
  • Absence of acute lower extremity pain or injury on the day of assessment
  • Not using any assistive devices (e.g., orthoses, canes) during measurement

You may not qualify if:

  • History of a foot deformity diagnosed during childhood
  • History of musculoskeletal injury involving the lower extremity or lumbar region within the past 12 months
  • Previous surgery involving the lower extremity or lumbar region
  • Any condition that may affect general motor function, balance, circulation, sensory function, or pain perception

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Fenerbahce University

Istanbul, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Pain

Condition Hierarchy (Ancestors)

Neurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Mehmet Burak Uyaroğlu

    Fenerbahce University

    STUDY DIRECTOR
  • Yeliz Çırak

    Fenerbahce University

    STUDY CHAIR
  • Gizem Demir Uzun

    Fenerbahce University

    PRINCIPAL INVESTIGATOR
  • Berfu Özdemir

    Fenerbahce University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Mehmet Burak Uyaroğlu, Asst Prof

CONTACT

Yeliz Çırak

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
1 Day
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

April 23, 2026

First Posted

May 6, 2026

Study Start

May 1, 2026

Primary Completion

May 1, 2026

Study Completion

May 1, 2026

Last Updated

May 6, 2026

Record last verified: 2026-05

Locations