Does the TAP Block Work Better Than the TFP Block for Relieving Pain

NCT06975735 | Completed

• 1 other identifier: 2025/184
• Study Type: interventional
• Target: 108
• Locations: 1 country
• Sites: 1

Brief Summary

Regional anesthetics, nerve blocks, and interfascial blocks are becoming more common in many types of surgery to help with pain after surgery. Most clinicians concur with the importance of reducing postoperative pain scores and facilitating early discharge. The transversalis fascia plane block (TFP) and transversus abdominis plane block (TA), which are done from the side of the abdomen, have been proven to be very useful in surgeries related to women's health, weight loss, and the colon. Research on the effectiveness of both procedures in robot-assisted laparoscopic prostatectomies (RALP) is insufficient. The aim was to see if using a transversalis fascia plane block (TFP) or a transversus abdominal plane (TAP) block with 0.25% bupivacaine helped reduce pain, speed up recovery, and shorten hospital stays for men undergoing robot-assisted radical prostatectomy (RALP).

Conditions

Pain

Keywords

prostatectomy, pain

Outcome Measures

Primary Outcomes (1)

• Reducing patient-controlled analgesic consumption

  The time to first analgesic request in the postoperative period

  From the patient's anesthesia induction in the operating room to the postoperative 24. hours

Study Arms (3)

TAP Group

ACTIVE COMPARATOR

Receiving TAP 20 ml bupivacaine 0.25%

Procedure: TAP Plane Block

TFP Group

ACTIVE COMPARATOR

Receiving TFP 20 ml bupivacaine 0.25%

Procedure: TFP Block

Control Group

NO INTERVENTION

Not receiving TAP or TFP

Interventions

TAP Plane Block PROCEDURE

The transversus abdominis plane block (TAPB) is a technically simple and safe form of regional anesthesia that can provide effective analgesia for 12 hours in patients with acute postoperative pain

Also known as: TAP Block

TAP Group

TFP Block PROCEDURE

The transversalis fascia plane block (TAPB) is a technically simple and safe form of regional anesthesia that can provide effective analgesia for 12 hours in patients with acute postoperative pain

TFP Group

Eligibility Criteria

• Age: 18 Years - 70 Years
• Gender Eligibility Details: only male patients
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• American Society of Anesthesiologists (ASA) Class I or II
• Having regular preoperative visits

You may not qualify if:

• Patients classified as ASA III or IV,
• Patients with coagulopathy
• Those with a history of allergies
• Significant Cardiac Disorders (Coronary Artery Disease, Arrhythmia, Electrocardiography Anomaly, Heart Failure, etc.)
• \. Those with bleeding diathesis and those receiving anticoagulant therapy 2. Those with a history of carotid artery stenosis, 3. Cardiovascular disease, 4. Hipertansiyon, 5. Chronic obstructive pulmonary disease, 6. Patients with a heart rhythm outside the sinus 7. Patients with a history of cerebrovascular disease 8. Alcoholism or psychiatric illness 9. Those with diabetes, 10. Contraindicated for TAP and TFP Block 11. Those with drug allergies

Sponsors & Collaborators

• TC Erciyes University: lead

Study Sites (1)

Kudret Doğru

Kayseri, Melikgazi, 38050, Turkey (Türkiye)

Location

Related Publications (2)

• Dal Moro F, Aiello L, Pavarin P, Zattoni F. Ultrasound-guided transversus abdominis plane block (US-TAPb) for robot-assisted radical prostatectomy: a novel '4-point' technique-results of a prospective, randomized study. J Robot Surg. 2019 Feb;13(1):147-151. doi: 10.1007/s11701-018-0858-6. Epub 2018 Jul 28.

  PMID: 30056612 BACKGROUND

• Cacciamani GE, Menestrina N, Pirozzi M, Tafuri A, Corsi P, De Marchi D, Inverardi D, Processali T, Trabacchin N, De Michele M, Sebben M, Cerruto MA, De Marco V, Migliorini F, Porcaro AB, Artibani W. Impact of Combination of Local Anesthetic Wounds Infiltration and Ultrasound Transversus Abdominal Plane Block in Patients Undergoing Robot-Assisted Radical Prostatectomy: Perioperative Results of a Double-Blind Randomized Controlled Trial. J Endourol. 2019 Apr;33(4):295-301. doi: 10.1089/end.2018.0761. Epub 2019 Jan 31.

  PMID: 30484332 BACKGROUND

MeSH Terms

Conditions

Pain

Condition Hierarchy (Ancestors)

Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Kudret Doğru, Prof. Dr.

  TC Erciyes University

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Prof. Dr. (MD)

Study Record Dates

• First Submitted: May 9, 2025
• First Posted: May 16, 2025
• Study Start: May 25, 2025
• Primary Completion: December 15, 2025
• Study Completion: December 18, 2025
• Last Updated: December 24, 2025

Record last verified: 2025-12

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)