NCT07558746

Brief Summary

This study aims to enroll intern doctors and have them sit one of three identical radiology exams. The only difference between them is an AI-assistant. The differences between these groups will be used to measure the extent of AI reliance among intern doctors in Palestine.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
159

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Apr 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
enrolling by invitation

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 1, 2026

Completed
9 days until next milestone

Study Start

First participant enrolled

April 10, 2026

Completed
20 days until next milestone

First Posted

Study publicly available on registry

April 30, 2026

Completed
1 day until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2026

Completed
Last Updated

April 30, 2026

Status Verified

March 1, 2026

Enrollment Period

21 days

First QC Date

April 1, 2026

Last Update Submit

April 23, 2026

Conditions

Keywords

AIPalestineIntern DoctorsAI-relianceRadiology

Outcome Measures

Primary Outcomes (2)

  • AI Reliance

    The extent of dependance of subjects on AI. It will be estimated based on a difference in mean score between the groups. We will also assess this outcome by creating an (AI-concordance field: for the intervention groups it will be how many times the subjects answered identically to the AI prompt, while for the control group it will be 0). AI reliance will be operationalized as: AI Reliance = Mean score improvement in the correct-AI group vs control Mean score decrement in the incorrect-AI group vs control We will compare the two different outcome measures to determine which better represents our outcome.

    Periprocedural

  • Exam time

    This will be defined as the length of time subjects spend completing the exam.

    Periprocedural

Secondary Outcomes (3)

  • Correlation of baseline characteristics with AI reliance

    Baseline

  • % of Subjects with a positive Perception of AI use in Radiology, and its correlation with AI reliance

    Baseline

  • % of radiology interest as a specialty and its correlation with AI reliance

    Baseline

Study Arms (3)

Control-No AI

NO INTERVENTION

Subjects in this arm will undergo the base exam, without an AI assistant, and without the knowledge that an AI assistant is used among other groups.

Experimental-Correct AI

EXPERIMENTAL

Subjects in this arm will undergo the base exam, with an AI assistant, that provides the correct answer.

Behavioral: AI prompt (Correct)

Sham Comparator-Incorrect AI

SHAM COMPARATOR

Subjects in this arm will undergo the base exam, with an AI assistant, that provides an incorrect answer.

Behavioral: AI prompt (Incorrect)

Interventions

This is a suggested answer in the guise of an AI assistant. The prompt was written by the authors and not an actual AI chat model. The suggested answer is correct.

Experimental-Correct AI

This is a suggested answer in the guise of an AI assistant. The prompt was written by the authors and not an actual AI chat model. The suggested answer is incorrect.

Sham Comparator-Incorrect AI

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Intern doctor in Palestine
  • Completion of at least 3 months from their 1 year internship
  • Confirmed prior training in radiologic interpretation

You may not qualify if:

  • Does not consent to the study
  • Completion of the internship
  • Non-completion of at least 3 months of their 1 year internship

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Al-Quds University

Abū Dīs, Palestinian Territories

Location

Related Publications (12)

  • Alchallah MO, Ismail H, Dia T, Shibani M, Alzabibi MA, Mohsen F, Turkmani K, Sawaf B. Assessing diagnostic radiology knowledge among Syrian medical undergraduates. Insights Imaging. 2020 Nov 23;11(1):124. doi: 10.1186/s13244-020-00937-9.

    PMID: 33226458BACKGROUND
  • Chen Y, Wu Z, Wang P, Xie L, Yan M, Jiang M, Yang Z, Zheng J, Zhang J, Zhu J. Radiology Residents' Perceptions of Artificial Intelligence: Nationwide Cross-Sectional Survey Study. J Med Internet Res. 2023 Oct 19;25:e48249. doi: 10.2196/48249.

    PMID: 37856181BACKGROUND
  • Chassagnon G, Dohan A. Artificial intelligence: from challenges to clinical implementation. Diagn Interv Imaging. 2020 Dec;101(12):763-764. doi: 10.1016/j.diii.2020.10.007. Epub 2020 Nov 10. No abstract available.

    PMID: 33187905BACKGROUND
  • Nakaura T, Higaki T, Awai K, Ikeda O, Yamashita Y. A primer for understanding radiology articles about machine learning and deep learning. Diagn Interv Imaging. 2020 Dec;101(12):765-770. doi: 10.1016/j.diii.2020.10.001. Epub 2020 Oct 26.

    PMID: 33121910BACKGROUND
  • Al-Karawi D, Al-Zaidi S, Helael KA, Obeidat N, Mouhsen AM, Ajam T, Alshalabi BA, Salman M, Ahmed MH. A Review of Artificial Intelligence in Breast Imaging. Tomography. 2024 May 9;10(5):705-726. doi: 10.3390/tomography10050055.

    PMID: 38787015BACKGROUND
  • Hardy M, Harvey H. Artificial intelligence in diagnostic imaging: impact on the radiography profession. Br J Radiol. 2020 Apr;93(1108):20190840. doi: 10.1259/bjr.20190840. Epub 2019 Dec 16.

    PMID: 31821024BACKGROUND
  • Hosny A, Parmar C, Quackenbush J, Schwartz LH, Aerts HJWL. Artificial intelligence in radiology. Nat Rev Cancer. 2018 Aug;18(8):500-510. doi: 10.1038/s41568-018-0016-5.

    PMID: 29777175BACKGROUND
  • Aquino GJ, Mastrodicasa D, Alabed S, Abohashem S, Wen L, Gill RR, Bardo DME, Abbara S, Hanneman K. Radiology: Cardiothoracic Imaging Highlights 2023. Radiol Cardiothorac Imaging. 2024 Apr;6(2):e240020. doi: 10.1148/ryct.240020.

    PMID: 38602468BACKGROUND
  • Banerjee I, Bhattacharjee K, Burns JL, Trivedi H, Purkayastha S, Seyyed-Kalantari L, Patel BN, Shiradkar R, Gichoya J. "Shortcuts" Causing Bias in Radiology Artificial Intelligence: Causes, Evaluation, and Mitigation. J Am Coll Radiol. 2023 Sep;20(9):842-851. doi: 10.1016/j.jacr.2023.06.025. Epub 2023 Jul 27.

    PMID: 37506964BACKGROUND
  • Brunye TT, Mitroff SR, Elmore JG. Artificial intelligence and computer-aided diagnosis in diagnostic decisions: 5 questions for medical informatics and human-computer interface research. J Am Med Inform Assoc. 2026 Feb 1;33(2):543-550. doi: 10.1093/jamia/ocaf123.

    PMID: 41101774BACKGROUND
  • Fontenele RC, Jacobs R. Unveiling the power of artificial intelligence for image-based diagnosis and treatment in endodontics: An ally or adversary? Int Endod J. 2025 Feb;58(2):155-170. doi: 10.1111/iej.14163. Epub 2024 Nov 11.

    PMID: 39526945BACKGROUND
  • Jeong J, Kim S, Pan L, Hwang D, Kim D, Choi J, Kwon Y, Yi P, Jeong J, Yoo SJ. Reducing the workload of medical diagnosis through artificial intelligence: A narrative review. Medicine (Baltimore). 2025 Feb 7;104(6):e41470. doi: 10.1097/MD.0000000000041470.

    PMID: 39928829BACKGROUND

MeSH Terms

Interventions

docusate sodium mixt. with phenolphtalein

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Masking Details
The analyst will also be blinded.
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Model Details: This study is a triple arm, triple blinded, parallel design randomized controlled trial. The study will measure how much intern doctors rely on AI assistance in radiologic interpretation and the behavioral impact of correct versus incorrect AI guidance. All interns will undergo a radiology exam with identical questions, and have their results compared across groups.
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 1, 2026

First Posted

April 30, 2026

Study Start

April 10, 2026

Primary Completion

May 1, 2026

Study Completion

May 1, 2026

Last Updated

April 30, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will not share

As the data includes private information, particularly in the form of exam scores, we will opt out of sharing the study data.

Locations