NCT07496489

Brief Summary

The purpose of this study is to compare a delayed-effects warning to an expanded warning developed in previous experiments on knowledge, harm perceptions, and willingness to try cannabis edibles. Additionally, this study will examine the effects of a corresponding icon on attention to and recall of the warning.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,250

participants targeted

Target at P75+ for not_applicable

Timeline
1mo left

Started May 2026

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
enrolling by invitation

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress28%
May 2026Aug 2026

First Submitted

Initial submission to the registry

March 20, 2026

Completed
7 days until next milestone

First Posted

Study publicly available on registry

March 27, 2026

Completed
2 months until next milestone

Study Start

First participant enrolled

May 28, 2026

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2026

Last Updated

May 29, 2026

Status Verified

March 1, 2026

Enrollment Period

2 months

First QC Date

March 20, 2026

Last Update Submit

May 28, 2026

Conditions

Keywords

Cannabisediblesmarijuanamarketingpackagingwarnings

Outcome Measures

Primary Outcomes (6)

  • Product appeal score

    One item to assess the appeal of the product. Results will be reported as means. Question: How appealing is this edible to you? Response options: (0) Not at all appealing to (10) Very appealing. Higher score denoting more appeal

    Minute 1

  • Perception of product safety score

    One item to assess the participants' perception of the safety of the product. Results will be presented as the frequency of each type of response. Question: How safe do you think it would be to eat this edible? Response options: (1) Not at all safe, (2) Slightly safe, (3) Somewhat safe, (4) Moderately safe, (5) Very safe. Higher score denoting more safe to eat

    Minute 1

  • Perceived likelihood of experiencing unwanted effects score

    One item to assess the participants' perception of the likelihood of experiencing unwanted effects. Results will be presented as the frequency of each type of response. Question: How likely are you to experience unwanted effects if you eat this edible? Response options: (1) Not at all likely, (2) Slightly likely, (3) Somewhat likely, (4) Moderately likely, (5) Very likely. Higher score denoting greater likelihood of experiencing side effects

    Minute 1

  • Interest in a free sample score

    One item to assess how interested a participant would be in a free sample of the product. Results will be presented as the frequency of each type of response. Question: How interested would you be in a free sample of this edible? Response options: (1) Not at all interested, (2) Slightly interested, (3) Somewhat interested, (4) Moderately interested, (5) Very interested. Higher score denoting more interest

    Minute 1

  • Concern about the risks of overconsumption due to warning score

    One item to assess how much the warning makes the participant concerned about the risks of overconsumption for participants randomized to view a package with a warning (intervention conditions only). Results will be presented as the frequency of each type of response. Question: How much does this warning make you concerned about potential risks from eating too much of this edible? Response options: (1) Not at all, (2) A little, (3) Somewhat, (4) Quite a bit, (5) A great deal. Higher score denotes more concern

    Minute 1

  • Improved understanding of safe consumption due to warning score

    One item to assess how much the warning gives the participant a better understanding of how to safely consume an edible (intervention conditions only). Results will be presented as the frequency of each type of response. Question: How much does this warning give you a better understanding of how to safely consume this edible? Response options: (1) Not at all, (2) a little, (3) somewhat, (4) quite a bit, (5) a great deal. Higher score denotes better understanding of safety

    Minute 1

Secondary Outcomes (2)

  • Warning recall

    Minute 1

  • Attention Score

    Minute 1

Study Arms (5)

No Warning Control

EXPERIMENTAL

One cannabis edibles package without a warning message.

Behavioral: No Warning Control

Delayed Effects Text Only

EXPERIMENTAL

One cannabis edibles package with a warning containing a delayed effects message

Behavioral: Delayed Effects Text Only

Delayed Effects Plus Icon

EXPERIMENTAL

One cannabis edibles package with a warning containing a delayed effects message and a corresponding icon.

Behavioral: Delayed Effects Plus Icon

Delayed Effects Plus Dose

EXPERIMENTAL

One cannabis edibles package with a warning containing delayed effects message and dosing instructions.

Behavioral: Delayed Effects Plus Dose

Delayed Effects Plus Dose Plus Adverse Effects

EXPERIMENTAL

One cannabis edibles package with a warning containing delayed effects, dosing instructions, and adverse effects message.

Behavioral: Delayed Effects Plus Dose Plus Adverse Effects

Interventions

Participants in the control condition will see an edible cannabis package without a warning message.

No Warning Control

Participants will see a cannabis edibles package with a warning containing a delayed effects message and a corresponding icon.

Delayed Effects Plus Icon

Participants will view a cannabis edibles package with a warning containing delayed effects message and dosing instructions.

Delayed Effects Plus Dose

Participants will see a cannabis edibles package with a warning message containing a delayed effects message.

Delayed Effects Text Only

Participants will view a cannabis edibles package with a warning containing delayed effects, dosing instructions, and adverse effects message.

Delayed Effects Plus Dose Plus Adverse Effects

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • English-speaking by self-selection
  • United States resident

You may not qualify if:

  • Already participated in a precursor project (IRB00104038, IRB000111438)
  • Eligible but demographic and user group strata have already been met

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Wake Forest University Health Sciences

Winston-Salem, North Carolina, 27157, United States

Location

MeSH Terms

Conditions

Marijuana Abuse

Condition Hierarchy (Ancestors)

Substance-Related DisordersChemically-Induced DisordersMental Disorders

Study Officials

  • Beth Reboussin, PhD

    Wake Forest University Health Sciences

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
OTHER
Intervention Model
PARALLEL
Model Details: Assign participants to view a cannabis edibles package with one of four variations of a warning and answer a series of questions assessing knowledge, harm perceptions, and willingness to try the product shown. One group will serve as the control and will see the same cannabis edibles package without a warning.
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 20, 2026

First Posted

March 27, 2026

Study Start

May 28, 2026

Primary Completion (Estimated)

August 1, 2026

Study Completion (Estimated)

August 1, 2026

Last Updated

May 29, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will not share

Locations