Smart Talk: Cannabis Awareness and Prevention Curriculum Evaluation

NCT07357454 | Not Yet Recruiting DMC

• 2 other identifiers: 804021R01DA060900-01A1
• Study Type: interventional
• Target: 10,800
• Locations: 1 country
• Sites: 1

Brief Summary

The Stanford REACH Lab's SMART TALK: Cannabis Awareness and Prevention Toolkit is a free, online educational resource to be used by educators to increase knowledge and awareness of cannabis and reduce use among youth. The aim of this study is to investigate the extent to which the curriculum changes middle and high school students' intentions to use and actual use of cannabis.

Conditions

Cannabis Use

Keywords

youth cannabis education health prevention

Outcome Measures

Primary Outcomes (1)

• Change in cannabis use

  Investigator-originated survey measures (questions) assess ever cannabis use \& past 30-day cannabis use. This outcome measure assesses cannabis use.

  Baseline to follow-up at approximately 182 weeks

Secondary Outcomes (1)

• Change in intention to use cannabis in the future

  Baseline to follow-up at approximately 182 weeks

Study Arms (2)

Smart Talk Cannabis Awareness and Prevention

EXPERIMENTAL

At the start of Year 2, schools will be randomized in a 1:1 ratio to either receive 'Stanford REACH Lab's Smart Talk: Cannabis Prevention and Awareness' curriculum or 'delay-in-treatment (standard of care)'. Students in these schools will receive the Stanford curriculum designed as a 5-session course administered in a school class-room setting.

Behavioral: Behavioral: Smart Talk Cannabis Awareness and Prevention

Delay in Treatment Group

EXPERIMENTAL

At the start of Year 2, schools randomized to the delay-in-treatment group will receive a standard of care for one year. After year 2, the delay-in-treatment group will crossover to receive 'Stanford REACH Lab's Healthy Futures: Cannabis Prevention and Awareness until year 5 (receive intervention for years 2 to 4).

Behavioral: Behavioral: Smart Talk Cannabis Awareness and Prevention

Interventions

Behavioral: Smart Talk Cannabis Awareness and Prevention BEHAVIORAL

Behavioral:Smart Talk includes 5 lessons, each providing activities, online quiz games, and worksheets in addition to presentations, resources, and other materials aimed at addressing key factors associated with youth cannabis use, including changing adolescents' attitudes towards and misperceptions about cannabis; increasing their refusal skills to pulls of marketing and social media; reducing stress and depression which have been linked to cannabis initiation and use; improving coping skills; and decreasing intentions and actual use of all cannabis products.

Delay in Treatment Group; Smart Talk Cannabis Awareness and Prevention

Eligibility Criteria

• Age: 10 Years - 20 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Middle school and high school students receiving health education at schools participating in the study

Sponsors & Collaborators

• Stanford University: lead
• National Institute on Drug Abuse (NIDA): collaborator

Study Sites (1)

Stanford University

Palo Alto, California, 94304, United States

Location

Study Officials

• Bonnie Halpern Felsher, Ph.D.

  Stanford University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor of Pediatrics, Stanford School of Medicine

Study Record Dates

• First Submitted: January 20, 2026
• First Posted: January 22, 2026
• Study Start (Estimated): September 1, 2026
• Primary Completion (Estimated): September 1, 2029
• Study Completion (Estimated): February 1, 2030
• Last Updated: June 8, 2026

Record last verified: 2026-06

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)