Clinical Management of Cardiovascular Risk Factors in Adult Patients: A Before-and-After Interventional Study

NCT07447362 | Recruiting

• 1 other identifier: UCAM-CVRISK-2024
• Study Type: interventional
• Target: 220
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to evaluate cardiovascular risk factors, clinical characteristics, and outcomes in adult patients attending an outpatient cardiology clinic. The research focuses on identifying predictors of adverse cardiovascular events, optimizing risk stratification, and improving preventive strategies in routine clinical practice. Data will be collected from patients receiving standard cardiology care without altering their treatment. The results are expected to contribute to better understanding of cardiovascular risk profiles and to support improvements in clinical decision-making and patient management.

Conditions

Cardiovascular Risk Factors; Hypertension; Dyslipidemia; Type 2 Diabetes Mellitus; Obesity; Overweight; Tobacco Use

Keywords

Cardiovascular prevention; Risk factor control; Medication adherence; Clinical follow-up

Outcome Measures

Primary Outcomes (1)

• Change in systolic blood pressure

  Change in systolic blood pressure (mmHg) measured under standardized conditions to evaluate the effect of structured clinical and pharmacological cardiovascular risk management.

  Baseline to 90 days

Secondary Outcomes (11)

• Change in diastolic blood pressure

  Baseline to 90 days

• Change in LDL cholesterol

  Baseline to 90 days

• Change in HbA1c

  Baseline to 90 days

• Change in body weight

  Baseline to 90 days

• Change in renal function (eGFR)

  Baseline to 90 days

Study Arms (1)

Structured Clinical Management

EXPERIMENTAL

Participants receive structured clinical follow-up with periodic assessment of cardiovascular risk factors and adjustment of pharmacological and lifestyle management according to current clinical guidelines over a 120-day follow-up period.

Other: Structured Cardiovascular Risk Management

Interventions

Structured Cardiovascular Risk Management OTHER

Protocol-based clinical management including periodic evaluation and adjustment of antihypertensive, lipid-lowering, antidiabetic, and lifestyle interventions according to routine clinical practice guidelines.

Structured Clinical Management

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age ≥18 years
• Presence of at least one cardiovascular risk factor (hypertension, diabetes, dyslipidemia, obesity, or smoking)
• Receiving outpatient clinical follow-up
• Ability to provide informed consent

You may not qualify if:

• Severe clinical instability requiring hospitalization
• Pregnancy
• End-stage renal disease or dialysis
• Inability to complete follow-up visits
• Refusal to participate

Sponsors & Collaborators

• Universidad Católica San Antonio de Murcia: lead

Study Sites (1)

CDIEM Medical Center - Outpatient Cardiology Clinic

Santiago, Santiago Metropolitan, Chile

RECRUITING

MeSH Terms

Conditions

Hypertension; Dyslipidemias; Diabetes Mellitus, Type 2; Obesity; Overweight; Tobacco Use; Medication Adherence

Condition Hierarchy (Ancestors)

Vascular Diseases; Cardiovascular Diseases; Lipid Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Diabetes Mellitus; Glucose Metabolism Disorders; Endocrine System Diseases; Overnutrition; Nutrition Disorders; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Behavior; Patient Compliance; Patient Acceptance of Health Care; Treatment Adherence and Compliance; Health Behavior

Study Officials

• José Abellán Alemán, MD, PhD

  Universidad Católica San Antonio de Murcia

  STUDY CHAIR

Central Study Contacts

Julio César Núñez Farías, MD, MSc (Cardiology)

CONTACT

+56965860130; llaillai@yahoo.es

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Cardiologist and Principal Investigator

Model Details: Participants receive structured clinical follow-up with periodic evaluation and adjustment of standard pharmacological therapy under routine clinical practice using a before-and-after design.

Study Record Dates

• First Submitted: February 24, 2026
• First Posted: March 3, 2026
• Study Start: July 24, 2024
• Primary Completion: July 24, 2026
• Study Completion (Estimated): October 24, 2026
• Last Updated: March 3, 2026

Record last verified: 2026-02

Data Sharing

• IPD Sharing: Will not share

Locations

CL (1)