Korea Acute Myocardial Infarction Registry

NCT07409441 | Not Yet Recruiting

• 1 other identifier: SMC 2025-10-089-007
• Study Type: observational
• Target: 20,000
• Locations: 1 country
• Sites: 2

Brief Summary

This multicentre observational registry study, the Korea Acute Myocardial Infarction Registry (KAMIR-7), aims to improve long-term prognosis in Korean patients with acute myocardial infarction (AMI) by establishing and operating a nationwide patient registry system. Participating hospitals across Korea, treating AMI patients, will contribute prospective clinical and health-related data. The registry system is web-based and designed to support various clinical and epidemiologic research initiatives, provide standardized data, and facilitate collaborative studies, including participation in international studies such as GRACE. The primary objectives are:

• To ensure sustainable patient enrollment and prospective follow-up systems that can support clinical and public health research.
• To create a resource for future research on new antiplatelet agents, stents, or interventional strategies.
• To provide data for nested case-control studies within the cohort, facilitating research on clinical characteristics, treatment courses, and outcomes in AMI patients.
• To identify new prognostic factors influencing patient outcomes and establish guidelines appropriate for Korean clinical practice.
• To address limitations of prior KAMIR studies, including short follow-up duration and limited heart failure-related data, and incorporate evolving treatment strategies, devices, and medications. Through systematic data collection and networked collaboration, this study will enable comprehensive analyses of long-term outcomes in Korean AMI patients, contribute to evidence-based optimization of treatment strategies, support development of prognostic tools specific to the Korean population, and inform health policy and clinical guideline refinement. The registry will also foster research collaboration among hospitals, investigators, and international study networks to advance the understanding and management of AMI in Korea.

Conditions

Myocardial Infarction, Acute

Keywords

Acute Myocardial Infarction; Percutaneous Coronary Intervention; Coronary Angiography; ST-Elevation Myocardial Infarction; Non-ST-Elevation Myocardial Infarction

Outcome Measures

Primary Outcomes (1)

• Major adverse cardiac events (MACE) during follow-up

  MACE is defined as a composite endpoint of cardiovascular death, recurrent myocardial infarction, and coronary revascularization.

  6, 12, 24, and 36 months after index procedure

Eligibility Criteria

• Age: 19 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Study participants are patients aged 19 years or older diagnosed with acute myocardial infarction who are enrolled at participating hospitals in Korea as part of the KAMIR-7 registry and followed for up to 3 years.

You may qualify if:

• Age ≥ 19 years
• Patients diagnosed with acute myocardial infarction (AMI) (either ST-segment elevation myocardial infarction \[STEMI\] or non-ST-segment elevation myocardial infarction \[NSTEMI\]), meeting both of the following:
• Elevated cardiac troponin above the 99th percentile upper reference limit
• Evidence of myocardial ischemia, as indicated by symptoms, electrocardiographic (ECG) changes, and/or imaging evidence

You may not qualify if:

• \- Patients who do not provide informed consent to participate in this study

Sponsors & Collaborators

• Samsung Medical Center: lead
• The Korean Society of Cardiology: collaborator

Study Sites (2)

Chonnam National University Hospital

Gwangju, South Korea

Location

Samsung Medical Center

Seoul, South Korea

Location

MeSH Terms

Conditions

Myocardial Infarction; ST Elevation Myocardial Infarction; Non-ST Elevated Myocardial Infarction

Condition Hierarchy (Ancestors)

Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Vascular Diseases; Infarction; Ischemia; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Necrosis

Central Study Contacts

KAMIR-7 CRA

CONTACT

+82-62-220-5845; ohhan523@naver.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 3 Years
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: February 8, 2026
• First Posted: February 13, 2026
• Study Start: March 1, 2026
• Primary Completion (Estimated): December 31, 2030
• Study Completion (Estimated): December 31, 2031
• Last Updated: March 10, 2026

Record last verified: 2026-02

Data Sharing

• IPD Sharing: Will not share

Locations

KR (2)