Registry of Acute Myocardial Infarction

NCT06252168 | Recruiting DMC

• 1 other identifier: CRI-211
• Study Type: observational
• Target: 97,500
• Locations: 1 country
• Sites: 1

Brief Summary

The Registry of Acute Myocardial Infarction (RAMI) aims at regular and centralized acquiring and processing standard information about verified and suspected cases of acute myocardial infarction (AMI), monitoring of AMI cases, and establishing AMI diagnosis based on standard diagnostic criteria by doctors involved in the registry. The RAMI obtains data from all medical institutions, which could potentially document any cases of suspected AMI.

Conditions

Myocardial Infarction, Acute

Keywords

Acute Myocardial Infarction; Acute Coronary Syndrome

Outcome Measures

Primary Outcomes (1)

• Early AMI lethality rate (%)

  Early acute myocardial infarction (AMI) lethality rate is calculated as percentage (%) of fatal outcomes that occurred within 28 days since onset of disease among subjects with verified or suspected AMI.

  28 days

Secondary Outcomes (1)

• 12-month AMI lethality rate (%)

  12 months

Eligibility Criteria

• Age: 20 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Study population icnludes all subjects with verified and suspected acute myocardial infarction (AMI) in the city of Tomsk (Russian Federation) regardless of disease treatment, outcome, and healthcare institution esablishing diagnosis.

You may qualify if:

• age of at least 20 years;
• being a resident or visitor of the city of Tomsk at a time of AMI onset;
• the presence of definite AMI or possible AMI. Definite AMI is diagnosed in the presence of characteristic ECG changes, regardless of clinical course and changes in serum enzymes; or the presence of typical pain syndrome, "ambiguous" ECG changes, and definite increase in the activity of serum enzymes i.e. exceeding the upper limit of normal by 25% or more; or macroscopically detected focus of myocardial necrosis and (or) fresh thrombotic occlusion of the coronary artery. Possible AMI is registered in the presence of typical pain syndrome with ambiguous ECG changes and an ambiguous (up to 25%) increase in the levels of serum enzymes; or the presence of obstruction in the lumen of at least one coronary artery by at least 50% and (or) the presence of a post-infarction scar in the myocardium with a diameter of 0.5 cm or more, while simultaneously excluding a non-coronary cause of death. In case of atypical clinical picture, ambiguous or absent ECG changes, when the enzyme levels are not determined or their activity does not reach a pathological level, AMI case is considered unconfirmed. In the absence of data that could confirm or not confirm AMI, the case is interpreted as "insufficient data"

You may not qualify if:

• none.

Sponsors & Collaborators

• Tomsk National Research Medical Center of the Russian Academy of Sciences: lead
• World Health Organization: collaborator

Study Sites (1)

Tomsk National Research Medical Center, Russian Academy of Sciences

Tomsk, Russia

RECRUITING

MeSH Terms

Conditions

Myocardial Infarction; Acute Coronary Syndrome

Condition Hierarchy (Ancestors)

Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Vascular Diseases; Infarction; Ischemia; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Necrosis

Study Officials

• Alexei N. Repin, MD, PhD

  Tomsk NRMC

  STUDY DIRECTOR

• Sergey A. Okrugin, MD, PhD

  Tomsk NRMC

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Sergey A. Okrugin, MD, PhD

CONTACT

+73822554111; sao@cardio-tomsk.ru

Nina D. Anfinogenova, PhD

CONTACT

+73822554111; cardio.intl@gmail.com

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 1, 2024
• First Posted: February 9, 2024
• Study Start: January 1, 1984
• Primary Completion (Estimated): December 31, 2049
• Study Completion (Estimated): December 31, 2050
• Last Updated: April 9, 2025

Record last verified: 2025-04

Data Sharing

• IPD Sharing: Will not share

Locations

RU (1)