NCT07379892|Completed
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Sponsor study identifier
observational
54
1 country
1
Study Start
June 1, 2023
Actual (reported)Primary Completion
December 15, 2023
Actual (reported)Study Completion
May 20, 2024
Actual (reported)The aim of this study was to evaluate the relationship between Triggering Receptor Expressed on Myeloid Cells-1 (TREM-1), Matrix Metalloproteinases-8 (MMP-8) and Tissue Inhibitors of Metalloproteinases-1 (TIMP-1) levels in peri-implant crevicular fluid (PICF) in peri-implantitis patients.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
May 20, 2024
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
June 1, 2023
Actual (reported)December 15, 2023
Actual (reported)May 20, 2024
Actual (reported)January 25, 2026
Actual (reported)February 2, 2026
Actual (reported)TREM-1, MMP-8 and TIMP-1 levels in PICF samples
TREM-1, MMP-8, and TIMP-1 levels in PICF samples were measured by ELISA method
1 month
Peri-implantitis is defined as bleeding on probing, suppuration, increased probing depth, clinical attachment loss, and radiographic bone loss
Peri-implant health is characterized by the absence of bleeding on probing, erythema, swelling, and suppuration in the peri-implant region
TREM-1, MMP-8 and TIPM-1 levels reseach in PICF samples
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
All patients had at least one implant, and this implant had been in place for at least one year since the implant-supported prosthesis was made.
Aydın Adnan Menderes University
Aydin, Turkey (Türkiye)
54 participants (actual enrollment reported by the registry).
First Submitted
January 25, 2026
First Posted
February 2, 2026
Study Start
June 1, 2023
Actual (reported)Effect of Smoking on Macrophage-related Chemokines Before and After Non-surgical Treatment of Initial Peri-implantitis
Contact the study team to confirm eligibility.
Primary Completion
December 15, 2023
Actual (reported)Study Completion
May 20, 2024
Actual (reported)Last Updated
February 9, 2026
Record last verified: 2026-02
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Source: ClinicalTrials.gov.
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