Evaluation of Fractalkine and Its Receptor in Peri-implantitis

NCT06685523 | Recruiting

• 1 other identifier: KU-DHF-KB-01
• Study Type: interventional
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

In this study, mechanical debridement group, Er:YAG laser group and diode laser group will be compared in terms of reducing peri-implant sulcus depth in the treatment of peri-implantitis.

Conditions

Peri-implantitis

Keywords

Er:YAG laser; Debridment; peri-implantitis

Outcome Measures

Primary Outcomes (1)

• Probing depth, clinical attachment loss

  Measurement will be made with a periodontal probe. The unit of measurement is millimetre. The primary outcome measures are interrelated.

  sixth month

Secondary Outcomes (1)

• gingival index, plaque index, sulcus blood index

  sixth month

Study Arms (4)

Group healty

NO INTERVENTION

Mechanical debridement group

EXPERIMENTAL

Procedure: Subgingival debridement

Er:YAG laser applied group

EXPERIMENTAL

Procedure: Er:YAG laser decontamination

Diyot laser applied group

EXPERIMENTAL

Procedure: Diyot laser decontamination

Interventions

Subgingival debridement PROCEDURE

To be applied 1 times (0. days)

Mechanical debridement group

Er:YAG laser decontamination PROCEDURE

To be applied 3 times

Er:YAG laser applied group

Diyot laser decontamination PROCEDURE

To be applied 3 times

Diyot laser applied group

Eligibility Criteria

• Age: 40 Years - 60 Years
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Probing depth of 4-6 mm, bone loss of at least 2 mm on X-ray and presence of inflammatory symptoms in soft tissue
• No systemic disease that may affect the outcome of the treatment
• Patients with healthy periodontium or patients with completed periodontal treatment
• Individuals at least 6 months after prosthesis loading on the implant
• Individuals who do not require further surgery for the treatment of peri-implantitis
• Implants with at least 2 mm keratised gingiva
• Individuals aged 40-60 years

You may not qualify if:

• Individuals undergoing radiation therapy
• Individuals who smoke and drink alcohol
• Individuals in pregnancy or lactation
• Individuals who have received antibiotic treatment in the last three months
• Individuals with parafunctional habits

Sponsors & Collaborators

• Kubilay BARIŞ: lead

Study Sites (1)

Kırıkkale University, Faculty of Dentistry, Department of Periodontology

Kırıkkale, 71000, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Peri-Implantitis

Condition Hierarchy (Ancestors)

Periodontal Diseases; Mouth Diseases; Stomatognathic Diseases

Central Study Contacts

Kubilay Barış, Dr.

CONTACT

+90-0553-973-64-77; kubilaybaris60@hotmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Assistant Professor

Model Details: Four group: * Peri-implant healty * Mechanical curette * Er:YAG laser * Diyot laser

Study Record Dates

• First Submitted: November 8, 2024
• First Posted: November 12, 2024
• Study Start: November 8, 2024
• Primary Completion: May 8, 2025
• Study Completion: May 15, 2025
• Last Updated: November 12, 2024

Record last verified: 2024-11

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)