Efficacy Evaluation Study of Vitamin C and Glutathione Liquid Sachet

NCT07379216 | Recruiting

• 1 other identifier: 25-103-A
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

The objective of this study is to evaluate the effect of liquid vitamin C and glutathione supplements on human skin condition improvement and anti-oxidation.

Conditions

Skin Condition; Anti-Oxidative Stress

Keywords

Vitamin C supplement; Glutathione supplement

Outcome Measures

Primary Outcomes (3)

• The change of skin tone

  Chroma Meter MM500 was utilized to measure face skin tone. Units: Individual Typology Angle (ITA°)

  Change from Baseline skin tone at 12 weeks

• The change of visible spots

  VISIA Complexion Analysis was utilized to measure visible spots on face. Units: the amount of detectable visible spots

  Change from Baseline visible spots at 12 weeks

• The change of UV spots

  VISIA Complexion Analysis was utilized to measure UV spots on face. Units: the amount of detectable UV spots

  Change from Baseline UV spots at 12 weeks

Secondary Outcomes (12)

• The change of skin hydration

  Change from Baseline skin hydration at 12 weeks

• The change of skin redness

  Change from Baseline skin redness at 12 weeks

• The change of skin melanin index

  Change from Baseline skin melanin index at 12 weeks

• The change of skin elasticity

  Change from Baseline skin elasticity at 12 weeks

• The change of brown spots

  Change from Baseline brown spots at 12 weeks

Other Outcomes (5)

• The change of self-assessment skin condition

  Change from Baseline skin condition at 12 weeks

• The change of self-assessment fatigue level

  Change from Baseline fatigue level at 12 weeks

• The change of self-assessment Low Immunity level

  Change from Baseline Low Immunity level at 12 weeks

Study Arms (2)

Placebo sachet

PLACEBO COMPARATOR

Dietary Supplement: Placebo sachet

Vitamin C and Glutathione Liquid Sachet

EXPERIMENTAL

Dietary Supplement: Vitamin C and Glutathione Liquid Sachet

Interventions

Vitamin C and Glutathione Liquid Sachet DIETARY_SUPPLEMENT

consume 1 sachet of the test samples daily for 12 consecutive weeks

Also known as: Lipo GLUTA-C

Vitamin C and Glutathione Liquid Sachet

Placebo sachet DIETARY_SUPPLEMENT

consume 1 sachet of the test samples daily for 12 consecutive weeks

Placebo sachet

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Healthy male or female adults, aged 18-65 years old;
• Commitment not to use products having activity comparable with that of the product to be tested during the study period;
• Free of any dermatological or systemic disorder that would interfere with results.

You may not qualify if:

• Subject with obvious skin surface damage;
• Subject who had oral or topical medication which may affect skin condition within 1 month;
• Individuals with known allergies to cosmetics, medications, or foods (especially those allergic to legumes/soy);
• Pregnant or breastfeeding individuals;
• Received facial laser therapy, chemical peeling in the past 2 months.
• Individuals unwilling to allow publication or public disclosure of photographs taken as part of the study results

Sponsors & Collaborators

• TCI Co., Ltd.: lead

Study Sites (1)

Chia Nan University of Pharmacy & Science

Pingtung City, 928, Taiwan

RECRUITING

MeSH Terms

Conditions

Skin Diseases

Interventions

Ascorbic Acid

Condition Hierarchy (Ancestors)

Skin and Connective Tissue Diseases

Intervention Hierarchy (Ancestors)

Sugar Acids; Acids, Acyclic; Carboxylic Acids; Organic Chemicals; Hydroxy Acids; Carbohydrates

Study Officials

• Chia-Hua Liang, Ph.D.

  Chia Nan University of Pharmacy ＆ Science

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Chia-Hua Liang, Ph.D.

CONTACT

+886-06-2664911; tinna_ling@mail.cnu.edu.tw

Ping Lin

CONTACT

+886-02-87977811; candice.lin@tci-bio.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 23, 2026
• First Posted: January 30, 2026
• Study Start: January 24, 2026
• Primary Completion (Estimated): May 18, 2026
• Study Completion (Estimated): June 1, 2026
• Last Updated: February 4, 2026

Record last verified: 2026-02

Locations

TW (1)