Efficacy Testing of Melon Oil Olive Pressed Candy Products

NCT05988567 | Completed

• 1 other identifier: 23-049-B
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

To assess melon and oil olive pressed candy on skin condition improvement

Conditions

Skin Condition

Outcome Measures

Primary Outcomes (10)

• The change of skin wrinkles

  VISIA Complexion Analysis System was utilized to measure skin wrinkles. Units: arbitrary units

  Change from Baseline skin wrinkles at 12 weeks

• The change of skin texture

  VISIA Complexion Analysis System was utilized to measure skin texture. Units: arbitrary units

  Change from Baseline skin texture at 12 weeks

• The change of skin melanin index

  Mexameter® MX18 was utilized to measure skin melanin index. Units: arbitrary units

  Change from Baseline skin melanin index at 12 weeks

• The change of skin erythema index

  Mexameter® MX18 was utilized to measure skin erythema index. Units: arbitrary units

  Change from Baseline skin erythema index at 12 weeks

• The change of skin L* value

  Chroma Meter MM500 was utilized to measure skin L\* value. Units: arbitrary units

  Change from Baseline L* value at 12 weeks

• The change of skin b* value

  Chroma Meter MM500 was utilized to measure skin b\* value. Units: arbitrary units

  Change from Baseline b* value at 12 weeks

• The change of skin ITA° value

  Chroma Meter MM500 was utilized to measure skin ITA° value. Units: arbitrary units

  Change from Baseline ITA° value at 12 weeks

• The change of skin spots

  VISIA Complexion Analysis System was utilized to measure skin spots. Units: arbitrary units

  Change from Baseline skin spots at 12 weeks

• The change of skin UV spots

  VISIA Complexion Analysis System was utilized to measure skin UV spots. Units: arbitrary units

  Change from Baseline skin UV spots at 12 weeks

• The change of skin brown spots

  VISIA Complexion Analysis System was utilized to measure skin brown spots. Units: arbitrary units

  Change from Baseline skin brown spots at 12 weeks

Secondary Outcomes (3)

• The change of TEAC of blood

  Change from Baseline TEAC at 12 weeks

• The change of SOD of blood

  Change from Baseline SOD at 12 weeks

• The change of GSH-Px of blood

  Change from Baseline GSH-Px at 12 weeks

Other Outcomes (1)

• The change of self-assessment skin and hair condition

  Change from Baseline skin and hair condition at 12 weeks

Study Arms (2)

Placebo candy

PLACEBO COMPARATOR

Dietary Supplement: Placebo candy

melon and oil olive pressed candy

EXPERIMENTAL

Dietary Supplement: melon and oil olive pressed candy

Interventions

Placebo candy DIETARY_SUPPLEMENT

consume 2 tablets per day

Placebo candy

melon and oil olive pressed candy DIETARY_SUPPLEMENT

consume 2 tablets per day

Also known as: Melon, oil olive and pomegranate blend pressed candy

melon and oil olive pressed candy

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Healthy adults aged above 18 years old
• ITA° value 20°-41°

You may not qualify if:

• Involuntary subjects.
• Subjects who have a history of skin diseases such as psoriasis, eczema, atopic dermatitis, severe acne; or suffer from other chronic systemic disease.
• Those with known cosmetic, drug or food allergies.
• Female who is pregnant or nursing or planning to become pregnant during the course of the study.
• Subjects who have taken oral or topical corticosteroids and other anti-inflammatory drugs in the past 1 month.
• Use of any products or drugs that affect skin color such as fruit acid, salicylic acid (such as Hydroquinone preparations) in the past 2 months.
• In the past 3 months, the test site has used retinoic acid preparations or undergone chemical peeling, laser, pulse light and other medical aesthetic therapists
• Subjects who can not avoid long-term sun exposure

Sponsors & Collaborators

• TCI Co., Ltd.: lead

Study Sites (1)

Chia Nan University of Pharmacy & Science

Tainan, Taiwan

Location

Related Publications (1)

• He Y, Bu Y, Chiang CF, Lin YH, Liang CH, Chan LP, Sun J. Multi-Plant Concentrated Powder Improved Skin Whitening: A Double-Blinded, Randomized, and Placebo-Controlled Clinical Study. J Cosmet Dermatol. 2025 Feb;24(2):e70011. doi: 10.1111/jocd.70011.

  PMID: 39927597 DERIVED

MeSH Terms

Conditions

Skin Diseases

Interventions

Olive Oil

Condition Hierarchy (Ancestors)

Skin and Connective Tissue Diseases

Intervention Hierarchy (Ancestors)

Dietary Fats, Unsaturated; Dietary Fats; Fats; Lipids; Fats, Unsaturated; Plant Oils; Oils; Food; Diet, Food, and Nutrition; Physiological Phenomena; Food and Beverages

Study Officials

• Chia-Hua Liang, Prof.

  Chia Nan University of Pharmacy ＆ Science

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 4, 2023
• First Posted: August 14, 2023
• Study Start: May 9, 2023
• Primary Completion: June 1, 2023
• Study Completion: December 31, 2023
• Last Updated: February 21, 2024

Record last verified: 2024-02

Locations

TW (1)