Prolonged Extubation in Gastric Cancer With OSA

NCT07362706 | Enrolling By Invitation DMC

• 1 other identifier: KYLL-202110-034-2
• Study Type: observational
• Target: 240
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to investigate the effect of prolonged tracheal intubation removal on the incidenceof postoperative complications in patients with gastric cancer complicated with severe obstructive sleepapnea.

Conditions

Gastric Cancer (GC); Obstructive Sleep Apnea

Keywords

Radical gastrectomy; Severe obstructive sleep apnea

Outcome Measures

Primary Outcomes (1)

• Postoperative complications

  The incidence of postoperative complications in patients with gastric cancer complicated with severe obstructive sleepapnea.

  48-72 hour

Interventions

Prolonging the duration of postoperative endotracheal intubation before extubation. PROCEDURE

The patients were divided into two groups, the extended tracheal intubationremoval time group (24-48h)and the non-extended tracheal intubation removal time group, and the incidenceof surgery-related complications and non-surgical-related complications in the two groups werecompared.

Eligibility Criteria

• Age: 18 Years - 85 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients with gastric cancer complicated with severe sleep apnea

You may qualify if:

• Patients preoperatively diagnosed with resectable gastric cancer
• Patients without distant organ metastasis
• Patients with preoperative Overnight Cardiorespiratory Sleep Testing (OCST) or Polysomnography (PSG) results showing Apnea-Hypopnea Index (AHI) \>30 events/hour and SaO₂ \<80%
• Patients with cardiopulmonary function deemed suitable for surgery
• Patients aged 18-85 years
• Patients who voluntarily joined this study and provided written informed consent

You may not qualify if:

• Patients with a history of or concurrent other malignant tumors
• Patients who underwent palliative resection
• Subjects who experienced acute cardiovascular or cerebrovascular events (e.g., acute cerebral infarction, acute coronary syndrome) within the past 3 months, or whose cardiovascular clinical symptoms/diseases are not well-controlled
• Patients with a history of psychotropic drug abuse that cannot be abstained, or those with psychiatric disorders
• Patients with concomitant diseases that, in the investigator's judgment, seriously endanger the patient's safety or affect the completion of the study

Sponsors & Collaborators

• Qilu Hospital of Shandong University: lead

Study Sites (1)

Qilu Hospital of Shandong University

Jinan, Shandong, 250000, China

Location

MeSH Terms

Conditions

Sleep Apnea, Obstructive; Stomach Neoplasms

Condition Hierarchy (Ancestors)

Sleep Apnea Syndromes; Apnea; Respiration Disorders; Respiratory Tract Diseases; Sleep Disorders, Intrinsic; Dyssomnias; Sleep Wake Disorders; Nervous System Diseases; Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Digestive System Diseases; Gastrointestinal Diseases; Stomach Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 27, 2025
• First Posted: January 23, 2026
• Study Start: January 1, 2023
• Primary Completion: February 10, 2026
• Study Completion (Estimated): June 30, 2028
• Last Updated: January 23, 2026

Record last verified: 2025-03

Locations

CN (1)