Efficacy of Ultrasound Guided Erector Spinae Plane Block Versus Ultrasound Guided Serratus Anterior Plane Block for Postoperative Pain Control Following Video-assisted Thoracoscopic Surgeries (VATS): Randomized Control Trial

NCT07360028 | Recruiting DMC

• 1 other identifier: FMASU MD 307/2025
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of the study is to compare the analgesic efficacy of Erector spinae plane block versus Serratus anterior plane block in patients undergoing video-assisted thoracoscopic surgeries.

Conditions

Post Operative Pain Control

Keywords

post operative pain control

Outcome Measures

Primary Outcomes (1)

• Visual analogue scale for Assessing postoperative pain control

  Assessing The difference in postoperative pain control between both groups as determined by assessing the visual analogue scale

  after ICU admission at 2, 4, 8, 16, 24 hours post operative.

Study Arms (2)

Erectror Spinae Plane Block

ACTIVE COMPARATOR

Ultrasound Guided block using 20 mL of 0.25% bupivacaine.

Procedure: Erector Spinae (ESP) Block with Bupivacaine (Marcaine®)

Serratus Anterior Plane Block

ACTIVE COMPARATOR

Ultrasound Guided block using 20 mL of 0.25% bupivacaine.

Procedure: Serratus anterior plane block (SAP)

Interventions

Erector Spinae (ESP) Block with Bupivacaine (Marcaine®) PROCEDURE

Ultrasound Guided Erector Spinae Plane block using 20 mL of 0.25% bupivacaine.

Erectror Spinae Plane Block

Serratus anterior plane block (SAP) PROCEDURE

Ultrasound Guided Serratus Anterior Plane Block using 20 mL of 0.25% bupivacaine.

Serratus Anterior Plane Block

Eligibility Criteria

• Age: 25 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients with American Society of Anesthesiology physical status ASA I, II and III.
• Patients aged between 25 and 70 years.
• patients undergoing video-assisted thoracoscopic surgeries (VATS), including pleurectomy, bullectomy, sympathectomy, esophagectomy, decortication, lobectomy, and pneumonectomy.

You may not qualify if:

• Patients below age of 25 or above age of 70.
• Patient refusal.
• Allergy to local anesthetic drugs.
• Bleeding or coagulation disorder.
• Psychiatric disorders.
• Infection at the needle entry site.
• Renal impairment (creatinine \>1.5 ).
• Hepatic impairment (Child B or C).
• Patients with known Cortisol related diseases such as Cushing's Syndrome or Addison's Disease.

Sponsors & Collaborators

• Ain Shams University: lead

Study Sites (1)

Ain-Shams University Hospitals

Cairo, Abbassia-Egypt, Egypt

RECRUITING

MeSH Terms

Interventions

Parapsychology; Dental Occlusion; Bupivacaine

Intervention Hierarchy (Ancestors)

Behavioral Sciences; Behavioral Disciplines and Activities; Dentistry; Dental Physiological Phenomena; Digestive System and Oral Physiological Phenomena; Anilides; Amides; Organic Chemicals; Aniline Compounds; Amines

Central Study Contacts

EMAN ZAGHLOUL MADY, MSc

CONTACT

00201013177848; Emanzaghloul@med.asu.edu.eg

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, CARE PROVIDER
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 14, 2026
• First Posted: January 22, 2026
• Study Start: December 1, 2025
• Primary Completion (Estimated): December 30, 2027
• Study Completion (Estimated): December 30, 2027
• Last Updated: January 22, 2026

Record last verified: 2026-01

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)